1AOG
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1YQN
| E. coli ispF double mutant | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-DIPHOSPHATE, GERANYL DIPHOSPHATE, ... | 著者 | Sgraja, T, Kemp, L.E, Ramsden, N, Hunter, W.N. | 登録日 | 2005-02-02 | 公開日 | 2005-07-12 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate. Acta Crystallogr.,Sect.F, 61, 2005
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1W57
| Structure of the Bifunctional IspDF from Campylobacter jejuni containing Zn | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, GERANYL DIPHOSPHATE, ISPD/ISPF BIFUNCTIONAL ENZYME, ... | 著者 | Gabrielsen, M, Bond, C.S, Hunter, W.N. | 登録日 | 2004-08-06 | 公開日 | 2004-10-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Hexameric Assembly of the Bifunctional Methylerythritol 2,4-Cyclodiphosphate Synthase and Protein-Protein Associations in the Deoxy-Xylulose-Dependent Pathway of Isoprenoid Precursor Biosynthesis J.Biol.Chem., 279, 2004
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1W77
| 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana | 分子名称: | 2C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CADMIUM ION, COPPER (II) ION, ... | 著者 | Gabrielsen, M, Kaiser, J, Rohdich, F, Eisenreich, W, Bacher, A, Bond, C.S, Hunter, W.N. | 登録日 | 2004-08-30 | 公開日 | 2006-02-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of a Plant 2C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Exhibits a Distinct Quaternary Structure Compared to Bacterial Homologues and a Possible Role in Feedback Regulation for Cytidine Monophosphate. FEBS J., 273, 2006
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1W6U
| Structure of human DECR ternary complex | 分子名称: | 2,4-DIENOYL-COA REDUCTASE, MITOCHONDRIAL PRECURSOR, HEXANOYL-COENZYME A, ... | 著者 | Alphey, M.S, Byres, E, Li, D, Hunter, W.N. | 登録日 | 2004-08-24 | 公開日 | 2004-10-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and Reactivity of Human Mitochondrial 2,4-Dienoyl-Coa Reductase: Enzyme-Ligand Interactions in a Distinctive Short-Chain Reductase Active Site J.Biol.Chem., 280, 2005
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242D
| MAD PHASING STRATEGIES EXPLORED WITH A BROMINATED OLIGONUCLEOTIDE CRYSTAL AT 1.65 A RESOLUTION. | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*(CBR)P*G)-3') | 著者 | Peterson, M.R, Harrop, S.J, McSweeney, S.M, Leonard, G.A, Thompson, A.W, Hunter, W.N, Helliwell, J.R. | 登録日 | 1996-06-20 | 公開日 | 1996-09-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | MAD Phasing Strategies Explored with a Brominated Oligonucleotide Crystal at 1.65A Resolution. J.Synchrotron Radiat., 3, 1996
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233D
| THE CRYSTAL STRUCTURE ANALYSIS OF D(CGCGAASSCGCG)2: A SYNTHETIC DNA DODECAMER DUPLEX CONTAINING FOUR 4'-THIO-2'-DEOXYTHYMIDINE NUCLEOTIDES | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*)-D(*(T49)P*(T49)P*)-D(*CP*GP*CP*G)-3') | 著者 | Boggon, T.J, Hancox, E.L, McAuley-Hecht, K.E, Connolly, B.A, Hunter, W.N, Brown, T, Walker, R.T, Leonard, G.A. | 登録日 | 1995-10-16 | 公開日 | 1996-06-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides. Nucleic Acids Res., 24, 1996
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1GYN
| Class II fructose 1,6-bisphosphate aldolase with Cadmium (not Zinc) in the active site | 分子名称: | CADMIUM ION, FRUCTOSE-BISPHOSPHATE ALDOLASE II | 著者 | Hall, D.R, Kemp, L.E, Leonard, G.A, Berry, A, Hunter, W.N. | 登録日 | 2002-04-27 | 公開日 | 2003-02-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase Acta Crystallogr.,Sect.D, 59, 2003
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1GUS
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1GY8
| Trypanosoma brucei UDP-galactose 4' epimerase | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-GALACTOSE 4-EPIMERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Shaw, M.P, Bond, C.S, Hunter, W.N. | 登録日 | 2002-04-21 | 公開日 | 2003-05-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-Resolution Crystal Structure of Trypanosoma Brucei Udp-Galactose 4'-Epimerase: A Potential Target for Structure-Based Development of Novel Trypanocides Mol.Biochem.Parasitol., 126, 2003
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1GXF
| CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH THE INHIBITOR QUINACRINE MUSTARD | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MALEIC ACID, QUINACRINE MUSTARD, ... | 著者 | Bond, C.S, Peterson, M.R, Vickers, T.J, Fairlamb, A.H, Hunter, W.N. | 登録日 | 2002-04-04 | 公開日 | 2004-05-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Two Interacting Binding Sites for Quinacrine Derivatives in the Active Site of Trypanothione Reductase: A Template for Drug Design J.Biol.Chem., 279, 2004
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1GUN
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1GUG
| MopII from Clostridium pasteurianum complexed with tungstate | 分子名称: | CHLORIDE ION, MOLYBDATE BINDING PROTEIN II, SODIUM ION, ... | 著者 | Schuettelkopf, A.W, Harrison, J.A, Hunter, W.N. | 登録日 | 2002-01-25 | 公開日 | 2002-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Passive Acquisition of Ligand by the Mopii Molbindin from Clostridium Pasteurianum: Structures of Apo and Oxyanion-Bound Forms J.Biol.Chem., 277, 2002
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1HH1
| THE STRUCTURE OF HJC, A HOLLIDAY JUNCTION RESOLVING ENZYME FROM SULFOLOBUS SOLFATARICUS | 分子名称: | HOLLIDAY JUNCTION RESOLVING ENZYME HJC | 著者 | Bond, C.S, Kvaratskhelia, M, Richard, D, White, M.F, Hunter, W.N. | 登録日 | 2000-12-18 | 公開日 | 2001-04-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of Hjc, a Holliday Junction Resolvase, from Sulfolobus Solfataricus Proc.Natl.Acad.Sci.USA, 98, 2001
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5OQ1
| Crystal structure of Serratia marcescens ChiX (used as MR model for superior PDB 5OPZ) | 分子名称: | CHLORIDE ION, ChiX, ZINC ION | 著者 | Owen, R.A, Fyfe, P.K, Lodge, A, Biboy, J, Vollmer, W, Hunter, W.N, Sargent, F. | 登録日 | 2017-08-10 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Structure and activity of ChiX: a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens. Biochem. J., 475, 2018
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5NRI
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5O87
| Crystal structure of wild type Aplysia californica AChBP in complex with nicotine | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dawson, A, Hunter, W.N, de Souza, J.O, Trumper, P. | 登録日 | 2017-06-12 | 公開日 | 2018-06-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6, 2019
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2XOX
| Crystal structure of pteridine reductase (PTR1) from Leishmania donovani | 分子名称: | PTERIDINE REDUCTASE, SULFATE ION | 著者 | Barrack, K.L, Tulloch, L.B, Burke, L.A, Fyfe, P.K, Hunter, W.N. | 登録日 | 2010-08-24 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of Recombinant Leishmania Donovani Pteridine Reductase Reveals a Disordered Active Site. Acta Crystallogr.,Sect.F, 67, 2011
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2XRE
| Detection of cobalt in previously unassigned human SENP1 structure | 分子名称: | COBALT (II) ION, GLYCEROL, SENTRIN-SPECIFIC PROTEASE 1 | 著者 | Rimsa, V, Eadsforth, T, Hay, R.T, Hunter, W.N. | 登録日 | 2010-09-14 | 公開日 | 2010-10-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The Role of Co2+ in the Crystallization of Human Senp1 and Comments on the Limitations of Automated Refinement Protocols Acta Crystallogr.,Sect.F, 67, 2011
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2Y5J
| Crystal structure of Burkholderia cenocepacia dihydropteroate synthase. | 分子名称: | 1,2-ETHANEDIOL, DIHYDROPTEROATE SYNTHASE | 著者 | Morgan, R.E, Batot, G.O, Dement, J.M, Rao, V.A, Eadsforth, T.C, Hunter, W.N. | 登録日 | 2011-01-13 | 公開日 | 2011-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystal Structures of Burkholderia Cenocepacia Dihydropteroate Synthase in the Apo-Form and Complexed with the Product 7,8-Dihydropteroate. Bmc Struct.Biol., 11, 2011
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2XPH
| Crystal structure of human SENP1 with the bound cobalt | 分子名称: | COBALT (II) ION, GLYCEROL, SENTRIN-SPECIFIC PROTEASE 1 | 著者 | Rimsa, V, Eadsforth, T, Hay, R.T, Hunter, W.N. | 登録日 | 2010-08-26 | 公開日 | 2010-09-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Role of Co2+ in the Crystallization of Human Senp1 and Comments on the Limitations of Automated Refinement Protocols Acta Crystallogr.,Sect.F, 67, 2011
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2Y4R
| CRYSTAL STRUCTURE OF 4-AMINO-4-DEOXYCHORISMATE LYASE FROM PSEUDOMONAS AERUGINOSA | 分子名称: | 1,2-ETHANEDIOL, 4-AMINO-4-DEOXYCHORISMATE LYASE, CHLORIDE ION, ... | 著者 | O'Rourke, P.E.F, Eadsforth, T.C, Fyfe, P.K, Shepard, S.M, Agacan, M, Hunter, W.N. | 登録日 | 2011-01-10 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Pseudomonas Aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme. Plos One, 6, 2011
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2Y5S
| Crystal structure of Burkholderia cenocepacia dihydropteroate synthase complexed with 7,8-dihydropteroate. | 分子名称: | 1,2-ETHANEDIOL, 7,8-DIHYDROPTEROATE, CHLORIDE ION, ... | 著者 | Morgan, R.E, Batot, G.O, Dement, J.M, Rao, V.A, Eadsforth, T.C, Hunter, W.N. | 登録日 | 2011-01-17 | 公開日 | 2011-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structures of Burkholderia Cenocepacia Dihydropteroate Synthase in the Apo-Form and Complexed with the Product 7,8-Dihydropteroate. Bmc Struct.Biol., 11, 2011
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5NRH
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2YHU
| Trypanosoma brucei PTR1 in complex with inhibitor WHF30 | 分子名称: | 3-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1-THIOPHEN-2-YLPROPAN-1-ONE, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Nerini, E, Dawson, A, Hunter, W.N, Costi, M.P. | 登録日 | 2011-05-06 | 公開日 | 2012-05-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. ACS Omega, 2, 2017
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