8DR7
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![BU of 8dr7 by Molmil](/molmil-images/mine/8dr7) | Open state of RFC:PCNA bound to a nicked dsDNA | 分子名称: | DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR3
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![BU of 8dr3 by Molmil](/molmil-images/mine/8dr3) | |
8DR5
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![BU of 8dr5 by Molmil](/molmil-images/mine/8dr5) | |
8DR1
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![BU of 8dr1 by Molmil](/molmil-images/mine/8dr1) | |
8DQW
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![BU of 8dqw by Molmil](/molmil-images/mine/8dqw) | |
8DQZ
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![BU of 8dqz by Molmil](/molmil-images/mine/8dqz) | Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction | 分子名称: | DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR0
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![BU of 8dr0 by Molmil](/molmil-images/mine/8dr0) | Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction | 分子名称: | DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DR6
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![BU of 8dr6 by Molmil](/molmil-images/mine/8dr6) | Closed state of RFC:PCNA bound to a nicked dsDNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DQX
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![BU of 8dqx by Molmil](/molmil-images/mine/8dqx) | Open state of RFC:PCNA bound to a 3' ss/dsDNA junction | 分子名称: | DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ... | 著者 | Schrecker, M, Hite, R.K. | 登録日 | 2022-07-20 | 公開日 | 2022-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
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8DCS
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![BU of 8dcs by Molmil](/molmil-images/mine/8dcs) | Cryo-EM structure of cyanopindolol-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Su, M, Paknejad, N, Hite, R.K, Huang, X.Y. | 登録日 | 2022-06-17 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies. Nat Commun, 13, 2022
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8DCR
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![BU of 8dcr by Molmil](/molmil-images/mine/8dcr) | Cryo-EM structure of dobutamine-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein | 分子名称: | DOBUTAMINE, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Su, M, Paknejad, N, Hite, R.K, Huang, X.Y. | 登録日 | 2022-06-17 | 公開日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies. Nat Commun, 13, 2022
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7STB
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![BU of 7stb by Molmil](/molmil-images/mine/7stb) | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | 登録日 | 2021-11-12 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
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7ST9
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![BU of 7st9 by Molmil](/molmil-images/mine/7st9) | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | 登録日 | 2021-11-12 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
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7STE
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![BU of 7ste by Molmil](/molmil-images/mine/7ste) | Rad24-RFC ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Checkpoint protein RAD24, ... | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | 登録日 | 2021-11-12 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
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7UNM
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![BU of 7unm by Molmil](/molmil-images/mine/7unm) | Human TMEM175 in an closed state | 分子名称: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | 著者 | Oh, S, Hite, R.K. | 登録日 | 2022-04-11 | 公開日 | 2022-06-29 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175. Elife, 11, 2022
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7UNL
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![BU of 7unl by Molmil](/molmil-images/mine/7unl) | Human TMEM175 in an open state | 分子名称: | Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION | 著者 | Oh, S, Hite, R.K. | 登録日 | 2022-04-11 | 公開日 | 2022-06-01 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175. Elife, 11, 2022
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7TD0
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![BU of 7td0 by Molmil](/molmil-images/mine/7td0) | Lysophosphatidic acid receptor 1-Gi complex bound to LPA | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | 登録日 | 2021-12-30 | 公開日 | 2022-02-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD2
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![BU of 7td2 by Molmil](/molmil-images/mine/7td2) | Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | 登録日 | 2021-12-30 | 公開日 | 2022-02-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD3
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![BU of 7td3 by Molmil](/molmil-images/mine/7td3) | Sphingosine-1-phosphate receptor 1-Gi complex bound to S1P | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | 登録日 | 2021-12-30 | 公開日 | 2022-02-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD1
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![BU of 7td1 by Molmil](/molmil-images/mine/7td1) | Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | 登録日 | 2021-12-30 | 公開日 | 2022-02-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD4
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![BU of 7td4 by Molmil](/molmil-images/mine/7td4) | Sphingosine-1-phosphate receptor 1-Gi complex bound to Siponimod | 分子名称: | 1-[[4-[(~{E})-~{N}-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-~{C}-methyl-carbonimidoyl]-2-ethyl-phenyl]methyl]azetidine-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | 登録日 | 2021-12-30 | 公開日 | 2022-02-09 | 最終更新日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7JM7
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![BU of 7jm7 by Molmil](/molmil-images/mine/7jm7) | Structure of human CLC-7/OSTM1 complex | 分子名称: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Schrecker, M, Hite, R. | 登録日 | 2020-07-31 | 公開日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. Elife, 9, 2020
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7JM6
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![BU of 7jm6 by Molmil](/molmil-images/mine/7jm6) | Structure of chicken CLC-7 | 分子名称: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Schrecker, M, Hite, R. | 登録日 | 2020-07-31 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. Elife, 9, 2020
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