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3FTM
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BU of 3ftm by Molmil
Class II ligase ribozyme product-template duplex, structure 1
分子名称: 5'-R(*CP*CP*AP*GP*UP*CP*GP*GP*AP*AP*CP*A)-3', 5'-R(*GP*UP*GP*UP*GP*AP*GP*GP*CP*UP*G)-3', MAGNESIUM ION, ...
著者Pitt, J.N, Ferre-D'Amare, A.R.
登録日2009-01-13
公開日2009-02-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-guided engineering of the regioselectivity of RNA ligase ribozymes.
J.Am.Chem.Soc., 131, 2009
3EGZ
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BU of 3egz by Molmil
Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
分子名称: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ...
著者Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R.
登録日2008-09-11
公開日2008-10-28
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch
Chem.Biol., 15, 2008
3IWN
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BU of 3iwn by Molmil
Co-crystal structure of a bacterial c-di-GMP riboswitch
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A
著者Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R.
登録日2009-09-02
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch.
Nat.Struct.Mol.Biol., 16, 2009
3FS0
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BU of 3fs0 by Molmil
Class II ligase ribozyme product-template duplex, structure 2
分子名称: 5'-R(*CP*CP*AP*GP*UP*CP*GP*GP*AP*AP*C)-3', 5'-R(*GP*GP*UP*GP*AP*GP*GP*CP*UP*G)-3', MAGNESIUM ION
著者Pitt, J.N, Ferre-D'Amare, A.R.
登録日2009-01-08
公開日2009-02-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-guided engineering of the regioselectivity of RNA ligase ribozymes.
J.Am.Chem.Soc., 131, 2009
3FU2
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BU of 3fu2 by Molmil
Cocrystal structure of a class-I preQ1 riboswitch
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, CALCIUM ION, PreQ1 riboswitch
著者Klein, D.J, Edwards, T.E, Ferre-D'Amare, A.R.
登録日2009-01-13
公開日2009-03-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase
Nat.Struct.Mol.Biol., 16, 2009
4TS2
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BU of 4ts2 by Molmil
Crystal structure of the Spinach RNA aptamer in complex with DFHBI, magnesium ions
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ...
著者Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R.
登録日2014-06-18
公開日2014-07-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.884 Å)
主引用文献Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.
Nat.Struct.Mol.Biol., 21, 2014
4TS0
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BU of 4ts0 by Molmil
Crystal structure of the Spinach RNA aptamer in complex with DFHBI, barium ions
分子名称: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, BARIUM ION, POTASSIUM ION, ...
著者Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R.
登録日2014-06-18
公開日2014-07-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.
Nat.Struct.Mol.Biol., 21, 2014
4XNR
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BU of 4xnr by Molmil
Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine
分子名称: ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch
著者Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R.
登録日2015-01-16
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Synthesis and applications of RNAs with position-selective labelling and mosaic composition.
Nature, 522, 2015
8EYW
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BU of 8eyw by Molmil
Beetroot dimer bound to ThT
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (49-MER)
著者Passalacqua, L.F.M, Ferre-D'Amare, A.R.
登録日2022-10-28
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.
Nat Commun, 14, 2023
4TZZ
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BU of 4tzz by Molmil
Co-crystals of the Ternary Complex Containing a T-box Stem I RNA, its Cognate tRNAGly, and B. subtilis YbxF protein, treated by removing lithium sulfate and increasing PEG3350 concentration from 20% to 45% post crystallization
分子名称: MAGNESIUM ION, Ribosome-associated protein L7Ae-like, T-box Stem I RNA, ...
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-11
公開日2014-09-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
8EYU
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BU of 8eyu by Molmil
Structure of Beetroot dimer bound to DFAME
分子名称: POTASSIUM ION, RNA (49-MER), methyl (2E)-3-{(4Z)-4-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl}prop-2-enoate
著者Passalacqua, L.F.M, Ferre-D'Amare, A.R.
登録日2022-10-28
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.
Nat Commun, 14, 2023
8EYV
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BU of 8eyv by Molmil
Structure of Beetroot dimer bound to DFHO
分子名称: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, POTASSIUM ION, RNA (45-MER)
著者Passalacqua, L.F.M, Ferre-D'Amare, A.R.
登録日2022-10-28
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.
Nat Commun, 14, 2023
8F0N
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BU of 8f0n by Molmil
Wobble Beetroot (A16U-U38G) dimer bound to DFHO
分子名称: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, POTASSIUM ION, RNA (49-MER)
著者Passalacqua, L.F.M, Ferre-D'Amare, A.R.
登録日2022-11-03
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.
Nat Commun, 14, 2023
4TZX
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BU of 4tzx by Molmil
Vibrio Vulnificus Adenine Riboswitch variant, grown in Mg2+
分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus Adenine Riboswitch
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-11
公開日2014-09-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
4TZY
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BU of 4tzy by Molmil
Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+
分子名称: ADENINE, MAGNESIUM ION, STRONTIUM ION, ...
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2014-07-11
公開日2014-09-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration.
Structure, 22, 2014
2Z75
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BU of 2z75 by Molmil
T. tengcongensis glmS ribozyme bound to glucosamine-6-phosphate
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, glmS ribozyme RNA, ...
著者Klein, D.J, Wilkinson, S.R, Been, M.D, Ferre-D'Amare, A.R.
登録日2007-08-15
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Requirement of helix P2.2 and nucleotide G1 for positioning the cleavage site and cofactor of the glmS ribozyme
J.Mol.Biol., 373, 2007
2Z74
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BU of 2z74 by Molmil
T. tengcongensis glmS ribozyme bound to glucose-6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, glmS ribozyme RNA, ...
著者Klein, D.J, Wilkinson, S.R, Been, M.D, Ferre-D'Amare, A.R.
登録日2007-08-15
公開日2007-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Requirement of helix P2.2 and nucleotide G1 for positioning the cleavage site and cofactor of the glmS ribozyme
J.Mol.Biol., 373, 2007
6UP0
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BU of 6up0 by Molmil
Structure of the Mango-III fluorescent aptamer bound to YO3-Biotin
分子名称: MAGNESIUM ION, Mango-III fluorescent aptamer, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-10-16
公開日2020-10-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fluorogenic aptamers resolve the flexibility of RNA junctions using orientation-dependent FRET.
Rna, 27, 2021
6V9B
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BU of 6v9b by Molmil
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
分子名称: POTASSIUM ION, RNA (28-MER), ~{N}-methyl-2-[2-[(~{E})-(1-methylquinolin-4-ylidene)methyl]-1,3-benzothiazol-3-yl]ethanamide
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-12-13
公開日2020-05-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.
Structure, 28, 2020
4XK0
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BU of 4xk0 by Molmil
Crystal structure of a tetramolecular RNA G-quadruplex in potassium
分子名称: BARIUM ION, POTASSIUM ION, RNA (5'-(*UP*GP*GP*GP*GP*U)-3')
著者Chen, M.C, Murat, P, Abecassis, K.A, Ferre-D'Amare, A.R, Balasubramanian, S.
登録日2015-01-09
公開日2015-02-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase.
Nucleic Acids Res., 43, 2015
6V9D
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BU of 6v9d by Molmil
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
分子名称: 2-[(E)-(1-methylquinolin-4(1H)-ylidene)methyl]-3-(2-oxopropyl)-1,3-benzothiazol-3-ium, BROMIDE ION, POTASSIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2019-12-13
公開日2020-05-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair.
Structure, 28, 2020
7LYJ
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BU of 7lyj by Molmil
SARS-CoV-2 frameshifting pseudoknot RNA
分子名称: IRIDIUM HEXAMMINE ION, MAGNESIUM ION, POTASSIUM ION, ...
著者Jones, C.P, Ferre-D'Amare, A.R.
登録日2021-03-07
公開日2021-05-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot.
Rna, 28, 2022
7MLW
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BU of 7mlw by Molmil
Burkholderia sp. TJI49 Guanidine-I riboswitch
分子名称: GUANIDINE, Guanidine-I riboswitch, MAGNESIUM ION, ...
著者Trachman, R.J, Ferre-D'Amare, A.R.
登録日2021-04-29
公開日2022-01-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An uncommon [K + (Mg 2+ ) 2 ] metal ion triad imparts stability and selectivity to the Guanidine-I riboswitch.
Rna, 27, 2021
7MKY
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BU of 7mky by Molmil
SARS-CoV-2 frameshifting pseudoknot RNA
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, COBALT HEXAMMINE(III), MAGNESIUM ION, ...
著者Jones, C.P, Ferre-D'Amare, A.R.
登録日2021-04-27
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot.
Rna, 28, 2022
4LCK
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BU of 4lck by Molmil
Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA
分子名称: MAGNESIUM ION, Ribosomal protein YbxF, STRONTIUM ION, ...
著者Zhang, J, Ferre-D'Amare, A.R.
登録日2013-06-21
公開日2013-07-31
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA.
Nature, 500, 2013

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