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1DK7
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BU of 1dk7 by Molmil
CRYSTAL STRUCTURE OF AN ISOLATED APICAL DOMAIN OF GROEL
分子名称: GROEL
著者Chen, L, Sigler, P.B.
登録日1999-12-06
公開日2000-01-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity.
Cell(Cambridge,Mass.), 99, 1999
1B3D
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BU of 1b3d by Molmil
STROMELYSIN-1
分子名称: CALCIUM ION, N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID, STROMELYSIN-1, ...
著者Chen, L, Rydel, T.J, Dunaway, C.M, Pikul, S, Dunham, K.M, Gu, F, Barnett, B.L.
登録日1998-12-09
公開日1999-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes.
J.Mol.Biol., 293, 1999
4FKH
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BU of 4fkh by Molmil
Crystal structure of porcine aminopeptidase-N complexed with alanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2012-06-13
公開日2012-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FKK
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BU of 4fkk by Molmil
Crystal structure of porcine aminopeptidase-N complexed with bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2012-06-13
公開日2012-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
5TIH
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BU of 5tih by Molmil
Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
分子名称: ACETATE ION, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ...
著者Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
2JTK
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BU of 2jtk by Molmil
A functional domain of a Wnt signal protein
分子名称: Dickkopf-related protein 2
著者Chen, L, Shao, Y, Huang, J, Zheng, J.
登録日2007-08-02
公開日2008-07-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural insight into the mechanisms of wnt signaling antagonism by dkk
J.Biol.Chem., 283, 2008
8GXE
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BU of 8gxe by Molmil
PTPN21 FERM PTP complex
分子名称: CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-19
公開日2023-09-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
2ICU
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BU of 2icu by Molmil
Crystal Structure of Hypothetical Protein YedK From Escherichia coli
分子名称: Hypothetical protein yedK
著者Chen, L, Liu, Z.J, Li, Y, Zhao, M, Rose, J, Ebihara, A, Yokoyama, S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-13
公開日2006-11-07
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Hypothetical Protein YedK From Escherichia coli
To be Published
8GWH
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BU of 8gwh by Molmil
PTPN21 PTP domain C1108S mutant in complex with SRC pTyr530 peptide
分子名称: SRC pTyr530 peptide, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-17
公開日2023-09-20
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
8GVV
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BU of 8gvv by Molmil
PTPN21 PTP domain C1108S mutant
分子名称: IODIDE ION, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-15
公開日2023-09-20
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
8GVL
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BU of 8gvl by Molmil
PTPN21 FERM
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-15
公開日2023-09-20
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
4HOM
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BU of 4hom by Molmil
Crystal structure of porcine aminopeptidase-N complexed with substance P
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2012-10-22
公開日2012-10-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FKE
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BU of 4fke by Molmil
Crystal structure of porcine aminopeptidase-N
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2012-06-13
公開日2012-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012
2KNO
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BU of 2kno by Molmil
NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1)
分子名称: Tensin-like C1 domain-containing phosphatase
著者Chen, L, Feng, R, Liu, C, Zhu, G.
登録日2009-08-27
公開日2010-09-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1)
To be Published
5TIK
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BU of 5tik by Molmil
Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
分子名称: Cysteine-rich protective antigen
著者Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F.
登録日2016-10-03
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
2LHK
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BU of 2lhk by Molmil
Structural analysis of a chaperone in type III secretion system
分子名称: L0052
著者Chen, L, Economou, A, Kalodimos, C.G.
登録日2011-08-11
公開日2011-12-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural instability tuning as a regulatory mechanism in protein-protein interactions.
Mol.Cell, 44, 2011
7C34
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BU of 7c34 by Molmil
Crystal structure of Serratia marcescens Chitinase B complexed with Berberine
分子名称: BERBERINE, Chitinase
著者Chen, L, Chen, J, Yang, Q.
登録日2020-05-11
公開日2020-05-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.938 Å)
主引用文献Crystal structure-guided design of berberine-based novel chitinase inhibitors.
J Enzyme Inhib Med Chem, 35, 2020
3LLP
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BU of 3llp by Molmil
1.8 Angstrom human fascin 1 crystal structure
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, Fascin, ...
著者Chen, L, Yang, S, Jakoncic, J, Zhang, J.J, Huang, X.-Y.
登録日2010-01-29
公開日2010-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Migrastatin analogues target fascin to block tumour metastasis.
Nature, 464, 2010
3MCA
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BU of 3mca by Molmil
Structure of the Dom34-Hbs1 Complex and implications for its role in No-Go decay
分子名称: Elongation factor 1 alpha-like protein, Protein dom34
著者Chen, L, Song, H.
登録日2010-03-28
公開日2010-10-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of the Dom34-Hbs1 complex and implications for no-go decay
Nat.Struct.Mol.Biol., 17, 2010
2P8T
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BU of 2p8t by Molmil
Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
分子名称: Hypothetical protein PH0730
著者Chen, L, Zhao, M, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhu, J, Swindell, J.T, Fu, Z.-Q, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-23
公開日2007-04-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hypothetical protein PH0730 from Pyrococcus horikoshii OT3
To be Published
2P91
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BU of 2p91 by Molmil
Crystal structure of Enoyl-[acyl-carrier-protein] reductase (NADH) from Aquifex aeolicus VF5
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH]
著者Chen, L, Li, Y, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Zhao, M, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-23
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Enoyl-[acyl-carrier-protein] reductase (NADH) from Aquifex aeolicus VF5
To be Published
2M1N
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BU of 2m1n by Molmil
Solution structure of a chaperone in type III secretion system
分子名称: Type III secretion system filament chaperone CesA
著者Chen, L, Economou, A, Kalodimos, C.
登録日2012-12-03
公開日2013-04-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Substrate-Activated Conformational Switch on Chaperones Encodes a Targeting Signal in Type III Secretion.
Cell Rep, 3, 2013
3RJQ
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BU of 3rjq by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-04-15
公開日2012-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3R0M
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BU of 3r0m by Molmil
Crystal structure of anti-HIV llama VHH antibody A12
分子名称: Llama VHH A12, SULFATE ION
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-03-08
公開日2012-03-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
4NZ8
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BU of 4nz8 by Molmil
Crystal structure of porcine aminopeptidase-N complexed with cleaved poly-alanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Chen, L, Lin, Y.L, Peng, G, Li, F.
登録日2013-12-11
公開日2013-12-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for multifunctional roles of mammalian aminopeptidase N.
Proc.Natl.Acad.Sci.USA, 109, 2012

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