3PE1
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![BU of 3pe1 by Molmil](/molmil-images/mine/3pe1) | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2010-10-25 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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3PE2
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![BU of 3pe2 by Molmil](/molmil-images/mine/3pe2) | Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011 | 分子名称: | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2010-10-25 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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5FBE
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![BU of 5fbe by Molmil](/molmil-images/mine/5fbe) | COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND2 | 分子名称: | Complement factor D, GLYCEROL, methyl 2-[[[(2~{S})-2-[[3-(trifluoromethyloxy)phenyl]carbamoyl]pyrrolidin-1-yl]carbonylamino]methyl]benzoate | 著者 | Ostermann, N, Zink, F. | 登録日 | 2015-12-14 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Small-molecule factor D inhibitors targeting the alternative complement pathway. Nat.Chem.Biol., 12, 2016
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3R0T
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![BU of 3r0t by Molmil](/molmil-images/mine/3r0t) | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279 | 分子名称: | 1,2-ETHANEDIOL, 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, ... | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2011-03-09 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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5FCR
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![BU of 5fcr by Molmil](/molmil-images/mine/5fcr) | MOUSE COMPLEMENT FACTOR D | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Complement factor D, DIMETHYL SULFOXIDE, ... | 著者 | Mac Sweeney, A. | 登録日 | 2015-12-15 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Small-molecule factor D inhibitors targeting the alternative complement pathway. Nat.Chem.Biol., 12, 2016
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5FBI
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![BU of 5fbi by Molmil](/molmil-images/mine/5fbi) | COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND 3b | 分子名称: | 3-[(2-aminocarbonyl-1~{H}-indol-5-yl)oxymethyl]benzoic acid, Complement factor D, GLYCEROL | 著者 | Ostermann, N, Zink, F. | 登録日 | 2015-12-14 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Small-molecule factor D inhibitors targeting the alternative complement pathway. Nat.Chem.Biol., 12, 2016
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7OFH
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![BU of 7ofh by Molmil](/molmil-images/mine/7ofh) | |
1QNJ
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![BU of 1qnj by Molmil](/molmil-images/mine/1qnj) | THE STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT ATOMIC RESOLUTION (1.1 A) | 分子名称: | ELASTASE, SODIUM ION, SULFATE ION | 著者 | Wurtele, M, Hahn, M, Hilpert, K, Hohne, W. | 登録日 | 1999-10-15 | 公開日 | 2000-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic Resolution Structure of Native Porcine Pancreatic Elastase at 1.1 A Acta Crystallogr.,Sect.D, 56, 2000
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4A3H
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![BU of 4a3h by Molmil](/molmil-images/mine/4a3h) | 2',4' DINITROPHENYL-2-DEOXY-2-FLURO-B-D-CELLOBIOSIDE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS AT 1.6 A RESOLUTION | 分子名称: | 2,4-DINITROPHENYL-2-DEOXY-2-FLUORO-BETA-D-CELLOBIOSIDE, PROTEIN (ENDOGLUCANASE) | 著者 | Davies, G.J, Brzozowski, A.M, Andersen, K, Schulein, M, Mackenzie, L, Withers, S.G. | 登録日 | 1998-07-22 | 公開日 | 1999-07-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase. Biochemistry, 37, 1998
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7ZCX
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![BU of 7zcx by Molmil](/molmil-images/mine/7zcx) | S-layer protein SlaA from Sulfolobus acidocaldarius at pH 4.0 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-deoxy-6-sulfo-beta-D-glucopyranose, ... | 著者 | Gambelli, L, Isupov, M.N, Daum, B. | 登録日 | 2022-03-29 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius. Elife, 13, 2024
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4QCL
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![BU of 4qcl by Molmil](/molmil-images/mine/4qcl) | Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and dCTP | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA TEMPLATE, ... | 著者 | Baranovskiy, A.G, Suwa, Y, Babayeva, N.D, Gu, J, Tahirov, T.H. | 登録日 | 2014-05-12 | 公開日 | 2014-11-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Activity and fidelity of human DNA polymerase alpha depend on primer structure J.Biol.Chem., 2018
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3A3H
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![BU of 3a3h by Molmil](/molmil-images/mine/3a3h) | CELLOTRIOSE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHERANS AT 1.6 A RESOLUTION | 分子名称: | ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Davies, G.J, Brzozowski, A.M, Andersen, K, Schulein, M. | 登録日 | 1998-02-01 | 公開日 | 1999-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Snapshots along an enzymatic reaction coordinate: analysis of a retaining beta-glycoside hydrolase. Biochemistry, 37, 1998
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2A3H
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![BU of 2a3h by Molmil](/molmil-images/mine/2a3h) | CELLOBIOSE COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHERANS AT 2.0 A RESOLUTION | 分子名称: | ENDOGLUCANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Davies, G.J, Brzozowski, A.M, Andersen, K, Schulein, M. | 登録日 | 1998-01-22 | 公開日 | 1999-03-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 A and its cellobiose complex at 2.0 A resolution Biochemistry, 37, 1998
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1BTU
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![BU of 1btu by Molmil](/molmil-images/mine/1btu) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4R)-1-TOLUENESULPHONYL-3-ETHYL-AZETIDIN-2-ONE-4-CARBOXYLIC ACID | 分子名称: | (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid, CALCIUM ION, ELASTASE, ... | 著者 | Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 1998-09-01 | 公開日 | 1999-02-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex. Biochemistry, 37, 1998
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2QEL
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![BU of 2qel by Molmil](/molmil-images/mine/2qel) | |
1QGF
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![BU of 1qgf by Molmil](/molmil-images/mine/1qgf) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3R, 4S)N-PARA-TOLUENESULPHONYL-3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wilmouth, R.C, Kassamally, S, Westwood, N.J, Sheppard, R.J, Claridge, T.D.W, Wright, P.A, Pritchard, G.J, Schofield, C.J. | 登録日 | 1999-04-27 | 公開日 | 1999-12-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanistic insights into the inhibition of serine proteases by monocyclic lactams. Biochemistry, 38, 1999
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1E36
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![BU of 1e36 by Molmil](/molmil-images/mine/1e36) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wright, P.A, Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 2000-06-06 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 'Ph-Jump' Crystallographic Analyses of Gamma-Lactam-Porcine Pancreatic Elastase Complexes Biochem.J., 351, 2000
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1E35
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![BU of 1e35 by Molmil](/molmil-images/mine/1e35) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-TOLUENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR TWO MINUTES | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wright, P.A, Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 2000-06-06 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 'Ph-Jump' Crystallographic Analyses of Gamma-Lactam-Porcine Pancreatic Elastase Complexes Biochem.J., 351, 2000
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1E34
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![BU of 1e34 by Molmil](/molmil-images/mine/1e34) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA- TOLUENESULPHONYL-3-ETHYL-4-(CARBOXYLIC ACID) PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR ONE MINUTE | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wright, P.A, Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 2000-06-06 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | `Ph-Jump' Crystallographic Analyses of Gamma-Lactam-Porcine Pancreatic Elastase Complexes Biochem.J., 351, 2000
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1E37
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![BU of 1e37 by Molmil](/molmil-images/mine/1e37) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 1 MINUTE | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wright, P.A, Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 2000-06-06 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | 'Ph-Jump' Crystallographic Analyses of Gamma-Lactam-Porcine Pancreatic Elastase Complexes Biochem.J., 351, 2000
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1E38
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![BU of 1e38 by Molmil](/molmil-images/mine/1e38) | PORCINE PANCREATIC ELASTASE COMPLEXED WITH (3S, 4S)N-PARA-NITROBENZENESULPHONYL -3-ETHYL-4-(CARBOXYLIC ACID)PYRROLIDIN-2-ONE SOAKED IN PH 9 BUFFER FOR 2 MINUTES | 分子名称: | (2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID, CALCIUM ION, ELASTASE, ... | 著者 | Wright, P.A, Wilmouth, R.C, Clifton, I.J, Schofield, C.J. | 登録日 | 2000-06-06 | 公開日 | 2000-10-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 'Ph-Jump' Crystallographic Analyses of Gamma-Lactam-Porcine Pancreatic Elastase Complexes Biochem.J., 351, 2000
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7K5L
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![BU of 7k5l by Molmil](/molmil-images/mine/7k5l) | Ebola virus VP40 octameric ring generated by an RNA oligonucleotide | 分子名称: | HSP RNA oligonucleotide, Matrix protein VP40 | 著者 | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | 登録日 | 2020-09-17 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form. Cell Rep, 35, 2021
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7K5D
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![BU of 7k5d by Molmil](/molmil-images/mine/7k5d) | Ebola virus VP40 octameric ring generated by a DNA oligonucleotide | 分子名称: | HSP DNA oligonucleotide, Matrix protein VP40 | 著者 | Landeras-Bueno, S, Wasserman, H, Salie, Z.L, Saphire, E.O. | 登録日 | 2020-09-16 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form. Cell Rep, 35, 2021
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7LC0
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![BU of 7lc0 by Molmil](/molmil-images/mine/7lc0) | Structure of D-Glucosaminate-6-phosphate Ammonia-lyase | 分子名称: | ACETIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Phillips, R.S. | 登録日 | 2021-01-09 | 公開日 | 2021-06-09 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and Mechanism of d-Glucosaminate-6-phosphate Ammonia-lyase: A Novel Octameric Assembly for a Pyridoxal 5'-Phosphate-Dependent Enzyme, and Unprecedented Stereochemical Inversion in the Elimination Reaction of a d-Amino Acid. Biochemistry, 60, 2021
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7LCE
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![BU of 7lce by Molmil](/molmil-images/mine/7lce) | Structure of D-Glucosaminate-6-phosphate Ammonia-lyase | 分子名称: | CALCIUM ION, D-glucosaminate-6-phosphate ammonia lyase, DIMETHYL SULFOXIDE | 著者 | Phillips, R.S. | 登録日 | 2021-01-10 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structure and Mechanism of d-Glucosaminate-6-phosphate Ammonia-lyase: A Novel Octameric Assembly for a Pyridoxal 5'-Phosphate-Dependent Enzyme, and Unprecedented Stereochemical Inversion in the Elimination Reaction of a d-Amino Acid. Biochemistry, 60, 2021
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