6BRO
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6DSZ
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7K48
| Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a | 著者 | Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A. | 登録日 | 2020-09-15 | 公開日 | 2020-12-02 | 最終更新日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin. Mol.Cell, 81, 2021
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6C1P
| HypoPP mutant | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, Ion transport protein, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-05 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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7MY4
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4EKW
| Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A) | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION | 著者 | Payandeh, J, Gamal El-Din, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2012-04-10 | 公開日 | 2012-05-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature, 486, 2012
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2AZE
| Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer | 分子名称: | Retinoblastoma-associated protein, Transcription factor Dp-1, Transcription factor E2F1 | 著者 | Rubin, S.M, Gall, A.L, Zheng, N, Pavletich, N.P. | 登録日 | 2005-09-10 | 公開日 | 2006-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. Cell(Cambridge,Mass.), 123, 2005
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2B5L
| Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein | 分子名称: | Nonstructural protein V, ZINC ION, damage-specific DNA binding protein 1 | 著者 | Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. | 登録日 | 2005-09-28 | 公開日 | 2006-02-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
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2B5N
| Crystal Structure of the DDB1 BPB Domain | 分子名称: | ISOPROPYL ALCOHOL, damage-specific DNA binding protein 1 | 著者 | Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. | 登録日 | 2005-09-28 | 公開日 | 2006-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
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2B5M
| Crystal Structure of DDB1 | 分子名称: | damage-specific DNA binding protein 1 | 著者 | Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. | 登録日 | 2005-09-28 | 公開日 | 2006-02-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
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2HYE
| Crystal Structure of the DDB1-Cul4A-Rbx1-SV5V Complex | 分子名称: | Cullin-4A, DNA damage-binding protein 1, Nonstructural protein V, ... | 著者 | Angers, S, Li, T, Yi, X, MacCoss, M.J, Moon, R.T, Zheng, N. | 登録日 | 2006-08-05 | 公開日 | 2006-10-03 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Nature, 443, 2006
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6C1M
| NavAb NormoPP mutant | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-METHYLGUANIDINE, CHAPSO, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-04 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.518 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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6C1K
| HypoPP mutant with ligand1 | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GUANIDINE, Ion transport protein, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-04 | 公開日 | 2018-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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6C1E
| NavAb NormoPP mutant | 分子名称: | (3ALPHA,5ALPHA,7ALPHA,8ALPHA,12ALPHA,14BETA,17ALPHA)-3,7,12-TRIHYDROXYCHOL-1-EN-24-AMIDE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5-BETA-24-NOR-CHOLANE-3(ALPHA),7(ALPHA),12(ALPHA)-TRIOL, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-04 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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6CHG
| Crystal structure of the yeast COMPASS catalytic module | 分子名称: | H3, Histone-lysine N-methyltransferase, H3 lysine-4 specific, ... | 著者 | Hsu, P.L, Li, H, Zheng, N. | 登録日 | 2018-02-22 | 公開日 | 2018-08-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.985 Å) | 主引用文献 | Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module. Cell, 174, 2018
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6DO4
| KLHDC2 ubiquitin ligase in complex with SelS C-end degron | 分子名称: | Kelch domain-containing protein 2, SELS C-END DEGRON | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | 登録日 | 2018-06-08 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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6DO3
| KLHDC2 ubiquitin ligase in complex with SelK C-end degron | 分子名称: | Kelch domain-containing protein 2, SelK C-end Degron | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | 登録日 | 2018-06-08 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.165 Å) | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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6DO5
| KLHDC2 ubiquitin ligase in complex with USP1 C-end degron | 分子名称: | Kelch domain-containing protein 2, USP1 C-END DEGRON | 著者 | Rusnac, D.V, Lin, H.C, Yen, H.C.S, Zheng, N. | 登録日 | 2018-06-08 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Recognition of the Diglycine C-End Degron by CRL2KLHDC2Ubiquitin Ligase. Mol. Cell, 72, 2018
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3C6N
| Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling | 分子名称: | (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | 著者 | Tan, X, Zheng, N, Hayashi, K. | 登録日 | 2008-02-04 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3I7P
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A | 分子名称: | DNA damage-binding protein 1, WD repeat-containing protein 40A | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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3I7O
| Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1 | 分子名称: | DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1 | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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3I7N
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1 | 分子名称: | DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1 | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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3I7H
| Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX | 分子名称: | DNA damage-binding protein 1, X protein | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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3I7L
| Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2 | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2 | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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3I7K
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX | 分子名称: | DNA damage-binding protein 1, X protein | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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