1KU6
 
 | | Fasciculin 2-Mouse Acetylcholinesterase Complex | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | | 著者 | Bourne, Y, Burmeister, W, Taylor, P, Marchot, P. | | 登録日 | 2002-01-21 | | 公開日 | 2003-12-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
EMBO J., 22, 2003
|
|
1J06
 | | Crystal structure of mouse acetylcholinesterase in the apo form | | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | 著者 | Bourne, Y, Taylor, P, Radic, Z, Marchot, P. | | 登録日 | 2002-11-07 | | 公開日 | 2003-02-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
|
|
1MAA
 | | MOUSE ACETYLCHOLINESTERASE CATALYTIC DOMAIN, GLYCOSYLATED PROTEIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... | | 著者 | Bourne, Y, Taylor, P, Bougis, P.E, Marchot, P. | | 登録日 | 1998-11-04 | | 公開日 | 1999-04-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.
J.Biol.Chem., 274, 1999
|
|
1JRZ
 | | Crystal structure of Arg402Tyr mutant flavocytochrome c3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | | 著者 | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2001-08-15 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase.
Biochemistry, 40, 2001
|
|
1JRY
 | | Crystal structure of Arg402Lys mutant flavocytochrome c3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | | 著者 | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2001-08-15 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase.
Biochemistry, 40, 2001
|
|
1JRX
 | | Crystal structure of Arg402Ala mutant flavocytochrome c3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | | 著者 | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2001-08-15 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase.
Biochemistry, 40, 2001
|
|
2PGZ
 | | Crystal structure of Cocaine bound to an ACh-Binding Protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COCAINE, Soluble acetylcholine receptor, ... | | 著者 | Hansen, S.B, Taylor, P. | | 登録日 | 2007-04-10 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
|
|
2PH9
 | | Galanthamine bound to an ACh-binding Protein | | 分子名称: | (-)-GALANTHAMINE, Soluble acetylcholine receptor, TETRAETHYLENE GLYCOL | | 著者 | Hansen, S.B, Taylor, P. | | 登録日 | 2007-04-10 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors.
J.Mol.Biol., 369, 2007
|
|
1D7H
 | | FKBP COMPLEXED WITH DMSO | | 分子名称: | AMMONIUM ION, DIMETHYL SULFOXIDE, PROTEIN (FK506-BINDING PROTEIN), ... | | 著者 | Burkhard, P, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1999-10-18 | | 公開日 | 1999-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
|
|
1D7J
 | | FKBP COMPLEXED WITH 4-HYDROXY-2-BUTANONE | | 分子名称: | 4-HYDROXY-2-BUTANONE, AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), ... | | 著者 | Burkhard, P, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1999-10-18 | | 公開日 | 1999-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
|
|
2WQZ
 | | Crystal structure of synaptic protein neuroligin-4 in complex with neurexin-beta 1: alternative refinement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NEUREXIN-1-BETA, ... | | 著者 | Fabrichny, I.P, Leone, P, Sulzenbacher, G, Comoletti, D, Miller, M.T, Taylor, P, Bourne, Y, Marchot, P. | | 登録日 | 2009-08-28 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural Analysis of the Synaptic Protein Neuroligin and its Beta-Neurexin Complex: Determinants for Folding and Cell Adhesion.
Neuron, 56, 2007
|
|
1D6O
 | | NATIVE FKBP | | 分子名称: | AMMONIUM ION, PROTEIN (FK506-BINDING PROTEIN), SULFATE ION | | 著者 | Burkhard, P, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1999-10-15 | | 公開日 | 1999-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
|
|
1D7I
 | | FKBP COMPLEXED WITH METHYL METHYLSULFINYLMETHYL SULFIDE (DSS) | | 分子名称: | AMMONIUM ION, METHYL METHYLSULFINYLMETHYL SULFIDE, PROTEIN (FK506-BINDING PROTEIN), ... | | 著者 | Burkhard, P, Taylor, P, Walkinshaw, M.D. | | 登録日 | 1999-10-18 | | 公開日 | 1999-10-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structures of small ligand-FKBP complexes provide an estimate for hydrophobic interaction energies.
J.Mol.Biol., 295, 2000
|
|
2XB6
 | | Revisited crystal structure of Neurexin1beta-Neuroligin4 complex | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Leone, P, Comoletti, D, Ferracci, G, Conrod, S, Garcia, S.U, Taylor, P, Bourne, Y, Marchot, P. | | 登録日 | 2010-04-07 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Insights Into the Exquisite Selectivity of Neurexin-Neuroligin Synaptic Interactions
Embo J., 29, 2010
|
|
3GUA
 | | Sulfates bound in the vestibule of AChBP | | 分子名称: | SULFATE ION, Soluble acetylcholine receptor | | 著者 | Hansen, S.B, Taylor, P. | | 登録日 | 2009-03-28 | | 公開日 | 2009-07-14 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance
J.Biol.Chem., 283, 2008
|
|
2BYP
 | | Crystal structure of Aplysia californica AChBP in complex with alpha- conotoxin ImI | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-CONOTOXIN IMI, SOLUBLE ACETYLCHOLINE RECEPTOR | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
|
|
2BYS
 | | CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA IN complex with lobeline | | 分子名称: | ACETYLCHOLINE-BINDING PROTEIN, LOBELINE | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-04 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
|
|
2BYR
 | | CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA in complex with methyllycaconitine | | 分子名称: | ACETYLCHOLINE-BINDING PROTEIN, METHYLLYCACONITINE | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
|
|
2BYQ
 | | Crystal structure of Aplysia californica AChBP in complex with epibatidine | | 分子名称: | EPIBATIDINE, SOLUBLE ACETYLCHOLINE RECEPTOR | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
|
|
2BYN
 | | Crystal structure of apo AChBP from Aplysia californica | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAETHYLENE GLYCOL, SOLUBLE ACETYLCHOLINE RECEPTOR, ... | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
|
|
1E39
 | | Flavocytochrome C3 from Shewanella frigidimarina histidine 365 mutated to alanine | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT, FUMARIC ACID, ... | | 著者 | Doherty, M.K, Pealing, S.L, Miles, C.S, Moysey, R, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2000-06-07 | | 公開日 | 2000-09-18 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of the Active Site Acid/Base Catalyst in a Bacterial Fumarate Reductase: A Kinetic and Crystallographic Study
Biochemistry, 39, 2000
|
|
1E8K
 | | Cyclophilin 3 Complexed With Dipeptide Ala-Pro | | 分子名称: | ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, PROLINE | | 著者 | Wu, S.Y, Dornan, J, Kontopidis, G, Taylor, P, Walkinshaw, M.D. | | 登録日 | 2000-09-25 | | 公開日 | 2001-09-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
|
|
4QAC
 | | X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 4-(4-methylpiperidin-1-yl)-6-(4-(trifluoromethyl)phenyl)pyrimidin-2-amine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(4-methylpiperidin-1-yl)-6-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine, Acetylcholine-binding protein, ... | | 著者 | Kaczanowska, K, Harel, M, Radic, Z, Changeux, J.-P, Finn, M.G, Taylor, P. | | 登録日 | 2014-05-03 | | 公開日 | 2014-07-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4QAA
 | | X-RAY STRUCTURE OF ACETYLCHOLINE BINDING PROTEIN (ACHBP) IN COMPLEX WITH 6-(4-Methoxyphenyl)-N4-octylpyrimidine-2,4-diamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(4-methoxyphenyl)-N~4~-octylpyrimidine-2,4-diamine, Acetylcholine-binding protein, ... | | 著者 | Kaczanowska, K, Harel, M, Radic, Z, Changeux, J.-P, Finn, M.G, Taylor, P. | | 登録日 | 2014-05-03 | | 公開日 | 2014-07-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4ZJS
 | | Crystal structure of a chimeric acetylcholine binding protein from Aplysia Californica (Ac-AChBP) containing the main immunogenic region (MIR) from the human alpha 1 subunit of the muscle nicotinic acetylcholine receptor in complex with anatoxin-A. | | 分子名称: | 1-[(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl]ethanone, Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor,Acetylcholine receptor subunit alpha,Soluble acetylcholine receptor | | 著者 | Talley, T.T, Bobango, J, Wu, J, Park, J.F, Luo, J, Lindsatrom, J, Taylor, P. | | 登録日 | 2015-04-29 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2301 Å) | | 主引用文献 | Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
J. Neurosci., 29, 2009
|
|
