5HK5
 
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5M3X
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5M3Y
 | | Crystal structure of human glycosylated angiotensinogen | | 分子名称: | Angiotensinogen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yan, Y, Read, R.J. | | 登録日 | 2016-10-17 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
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4Z9G
 | | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395 in a hexagonal setting with translational non-crystallographic symmetry | | 分子名称: | 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1, OLEIC ACID, ... | | 著者 | Dore, A.S, Bortolato, A, Hollenstein, K, Cheng, R.K.Y, Read, R.J, Marshall, F.H. | | 登録日 | 2015-04-10 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.183 Å) | | 主引用文献 | Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Curr Mol Pharmacol, 10, 2017
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2CLW
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2CEO
 | | thyroxine-binding globulin complex with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN | | 著者 | Zhou, A, Wei, Z, Read, R.J, Carrell, R.W. | | 登録日 | 2006-02-08 | | 公開日 | 2006-08-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Mechanism for the Carriage and Release of Thyroxine in the Blood.
Proc.Natl.Acad.Sci.USA, 103, 2006
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1VYX
 | | Solution structure of the KSHV K3 N-terminal domain | | 分子名称: | ORF K3, ZINC ION | | 著者 | Dodd, R.B, Allen, M.D, Brown, S.E, Sanderson, C.M, Duncan, L.M, lehner, P.J, Bycroft, M, Read, R.J. | | 登録日 | 2004-05-07 | | 公開日 | 2004-10-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Kaposi'S Sarcoma-Associated Herpesvirus K3 N-Terminal Domain Reveals a Novel E2-Binding C4Hc3-Type Ring Domain
J.Biol.Chem., 279, 2004
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1B3K
 | | Plasminogen activator inhibitor-1 | | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | | 著者 | Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. | | 登録日 | 1998-12-11 | | 公開日 | 1999-12-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion.
Structure Fold.Des., 7, 1999
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4A5M
 | | Redox regulator HypR in its oxidized form | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR | | 著者 | Palm, G.J, Waack, P, Read, R.J, Hinrichs, W. | | 登録日 | 2011-10-26 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Nucleic Acids Res., 40, 2012
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3ZR6
 | | STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J. | | 登録日 | 2011-06-14 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4A5N
 | | Redoxregulator HypR in its reduced form | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR | | 著者 | Palm, G.J, Waack, P, Read, R.J, Hinrichs, W. | | 登録日 | 2011-10-26 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Nucleic Acids Res., 40, 2012
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3ZR5
 | | STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J. | | 登録日 | 2011-06-14 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4AUT
 | | Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis | | 分子名称: | DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C. | | 登録日 | 2012-05-21 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis.
Sci. Transl. Med., 4, 2012
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8AXG
 | | Crystal structure of Fusobacterium nucleatum fusolisin protease | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fusolisin, ... | | 著者 | Isupov, M.N, Wiener, R, Rouvinski, A, Fahoum, J, Kumar, M, Read, R.J. | | 登録日 | 2022-08-31 | | 公開日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of Fusobacterium nucleatum fusolisin protease
To Be Published
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2RIW
 | | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2WXW
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2WY1
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2VDY
 | | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | | 著者 | Zhou, A, Wei, Z, Read, R.J. | | 登録日 | 2007-10-13 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
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2WY0
 | | Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | | 分子名称: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | 著者 | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | 登録日 | 2009-11-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
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2VDX
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2WXY
 | | Crystal structure of mouse angiotensinogen in the reduced form | | 分子名称: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | | 著者 | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | | 登録日 | 2009-11-11 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
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2WXZ
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2WXX
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1QOH
 | | A MUTANT SHIGA-LIKE TOXIN IIE | | 分子名称: | SHIGA-LIKE TOXIN IIE B SUBUNIT | | 著者 | Pannu, N.S, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | | 登録日 | 1999-11-08 | | 公開日 | 2000-07-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A Mutant Shiga-Like Toxin Iie Bound to its Receptor Gb(3): Structure of a Group II Shiga-Like Toxin with Altered Binding Specificity
Structure, 8, 2000
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2X0B
 | | Crystal structure of human angiotensinogen complexed with renin | | 分子名称: | ANGIOTENSINOGEN, RENIN | | 著者 | Zhou, A, Wei, Z, Yan, Y, Carrell, R.W, Read, R.J. | | 登録日 | 2009-12-08 | | 公開日 | 2010-10-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (4.33 Å) | | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
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