2SRC
| CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TYROSINE-PROTEIN KINASE SRC | 著者 | Xu, W, Doshi, A, Lei, M, Eck, M.J, Harrison, S.C. | 登録日 | 1998-12-29 | 公開日 | 1999-07-22 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol.Cell, 3, 1999
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6AHV
| Crystal structure of human RPP40 | 分子名称: | Ribonuclease P protein subunit p40 | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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6AHR
| Cryo-EM structure of human Ribonuclease P | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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3CRU
| Structural characterization of an engineered allosteric protein | 分子名称: | GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme | 著者 | Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. | 登録日 | 2008-04-07 | 公開日 | 2009-02-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
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3CRT
| Structural characterization of an engineered allosteric protein | 分子名称: | GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme | 著者 | Sagermann, M, Chapleau, R, DeLorimier, E, Lei, M. | 登録日 | 2008-04-07 | 公開日 | 2009-02-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Using affinity chromatography to engineer and characterize pH-dependent protein switches. Protein Sci., 18, 2009
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4M7C
| Crystal structure of the TRF2-binding motif of SLX4 in complex with the TRFH domain of TRF2 | 分子名称: | Peptide from Structure-specific endonuclease subunit SLX4, Telomeric repeat-binding factor 2 | 著者 | Wan, B, Chen, Y, Wu, J, Liu, Y, Lei, M. | 登録日 | 2013-08-12 | 公開日 | 2013-09-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres Cell Rep, 4, 2013
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6AGB
| Cryo-EM structure of yeast Ribonuclease P | 分子名称: | RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ... | 著者 | Lan, P, Tan, M, Wu, J, Lei, M. | 登録日 | 2018-08-10 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural insight into precursor tRNA processing by yeast ribonuclease P. Science, 362, 2018
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2L3N
| Solution structure of Rap1-Taz1 fusion protein | 分子名称: | DNA-binding protein rap1,Telomere length regulator taz1 | 著者 | Zhou, Z.R, Wang, F, Chen, Y, Lei, M, Hu, H. | 登録日 | 2010-09-19 | 公開日 | 2011-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
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6MLC
| PHD6 domain of MLL3 in complex with histone H4 | 分子名称: | GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ... | 著者 | Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-09-27 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun, 10, 2019
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5DOF
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5DOI
| Crystal structure of Tetrahymena p45N and p19 | 分子名称: | Telomerase associated protein p45, Telomerase-associated protein 19 | 著者 | Wan, B, Tang, T, Wu, J, Lei, M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex Nat.Struct.Mol.Biol., 22, 2015
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5DOK
| Crystal structure of Tetrahymena p45C | 分子名称: | MAGNESIUM ION, Telomerase associated protein p45 | 著者 | Wan, B, Tang, T, Wu, J, Lei, M. | 登録日 | 2015-09-11 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex Nat.Struct.Mol.Biol., 22, 2015
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5F59
| The crystal structure of MLL3 SET domain | 分子名称: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-04 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F6L
| The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | 分子名称: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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5F5E
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5F6K
| Crystal structure of the MLL3-Ash2L-RbBP5 complex | 分子名称: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Li, Y, Lei, M, Chen, Y. | 登録日 | 2015-12-06 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | 主引用文献 | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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3L82
| X-ray Crystal structure of TRF1 and Fbx4 complex | 分子名称: | F-box only protein 4, Telomeric repeat-binding factor 1 | 著者 | Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. | 登録日 | 2009-12-29 | 公開日 | 2010-03-09 | 最終更新日 | 2013-09-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
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3NBH
| Crystal structure of human RMI1C-RMI2 complex | 分子名称: | RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | 著者 | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | 登録日 | 2010-06-03 | 公開日 | 2010-09-22 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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6AHU
| Cryo-EM structure of human Ribonuclease P with mature tRNA | 分子名称: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | 著者 | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | 登録日 | 2018-08-20 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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3NBI
| Crystal structure of human RMI1 N-terminus | 分子名称: | RecQ-mediated genome instability protein 1 | 著者 | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | 登録日 | 2010-06-03 | 公開日 | 2010-09-22 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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3OIP
| Crystal structure of Yeast telomere protein Cdc13 OB1 | 分子名称: | Cell division control protein 13 | 著者 | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | 登録日 | 2010-08-19 | 公開日 | 2010-11-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.504 Å) | 主引用文献 | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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3OWT
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3OIQ
| Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1 | 分子名称: | Cell division control protein 13, DNA polymerase alpha catalytic subunit A | 著者 | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | 登録日 | 2010-08-19 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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8HMD
| base module state 2 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HMF
| head module state 2 of Tetrahymena IFT-A | 分子名称: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | 著者 | Ma, Y, Wu, J, Lei, M. | 登録日 | 2022-12-03 | 公開日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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