7Y28
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | 分子名称: | 1-[6-(3-fluorophenyl)benzimidazol-1-yl]-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | 著者 | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | 登録日 | 2022-06-09 | 公開日 | 2023-07-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y3S
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | 分子名称: | 1-(6-bromanyl-7-methyl-imidazo[4,5-b]pyridin-3-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | 著者 | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | 登録日 | 2022-06-12 | 公開日 | 2023-07-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y1W
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | 分子名称: | (2R,3S)-2-[3-[4,5-bis(chloranyl)benzimidazol-1-yl]propyl]piperidin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | 著者 | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | 登録日 | 2022-06-09 | 公開日 | 2023-07-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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7Y1H
| Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 | 分子名称: | 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... | 著者 | Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. | 登録日 | 2022-06-08 | 公開日 | 2023-07-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023
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8I70
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8I6Z
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6O7C
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6O7A
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6JQE
| The structural basis of the beta-carbonic anhydrases CafD (wild type) of the filamentous fungus Aspergillus fumigatus | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | 登録日 | 2019-03-30 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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6JQC
| The structural basis of the beta-carbonic anhydrase CafC (wild type) of the filamentous fungus Aspergillus fumigatus | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | 登録日 | 2019-03-30 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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6JQD
| The structural basis of the beta-carbonic anhydrase CafC (L25G and L78G mutant) of the filamentous fungus Aspergillus fumigatus | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | 登録日 | 2019-03-30 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | The structural basis of the low catalytic activities of the two minor beta-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus. J.Struct.Biol., 208, 2019
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8OSB
| TWIST1-TCF4-ALX4 complex on specific DNA | 分子名称: | DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ... | 著者 | Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J. | 登録日 | 2023-04-18 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | DNA-guided transcription factor cooperativity shapes face and limb mesenchyme. Cell, 187, 2024
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6O6J
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3ATT
| Crystal structure of Rv3168 with ATP | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Kim, Y.-G, Kim, S, Nguyen, C.M.T, Kim, K.-J. | 登録日 | 2011-01-13 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis Rv3168: a putative aminoglycoside antibiotics resistance enzyme Proteins, 79, 2011
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3ATS
| Crystal structure of Rv3168 | 分子名称: | CALCIUM ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kim, Y.-G, Kim, S, Nguyen, C.M.T, Kim, K.-J. | 登録日 | 2011-01-13 | 公開日 | 2011-08-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Crystal structure of Mycobacterium tuberculosis Rv3168: a putative aminoglycoside antibiotics resistance enzyme Proteins, 79, 2011
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6K8W
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6K8S
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6K8U
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6K8V
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6K8T
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7CXW
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (C116 flipped form) | 分子名称: | ACETATE ION, Carbonic anhydrase | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7CXX
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (disulfide-bonded form) | 分子名称: | ACETATE ION, Carbonic anhydrase, SULFATE ION | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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7CXY
| Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (zinc-bound form) | 分子名称: | Carbonic anhydrase, ZINC ION | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J, Kim, N.J, Hong, S. | 登録日 | 2020-09-02 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus. J.Struct.Biol., 213, 2021
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6IWB
| Crystal structure of a computationally designed protein (LD3) in complex with BCL-2 | 分子名称: | Apolipoprotein E, Apoptosis regulator Bcl-2,Apoptosis regulator Bcl-2, SULFATE ION | 著者 | Kim, S, Kwak, M.J, Oh, B.-H, Correia, B.E, Gainza, P. | 登録日 | 2018-12-05 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy. Nat.Biotechnol., 38, 2020
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4RDI
| Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, tRNA threonylcarbamoyladenosine dehydratase | 著者 | Park, S.Y, Kim, S, Lee, H. | 登録日 | 2014-09-19 | 公開日 | 2015-08-05 | 最終更新日 | 2015-10-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N(6)-Threonylcarbamoyladenosine Dehydratase Activity. J.Mol.Biol., 427, 2015
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