4KQ3
 
 | | Crystal structure of Anti-IL-17A antibody CNTO3186 | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO3186 heavy chain, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2013-05-14 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural evidence for a constrained conformation of short CDR-L3 in antibodies.
Proteins, 82, 2014
|
|
6AL4
 | |
4KMT
 | | Crystal structure of human germline antibody 5-51/O12 | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SULFATE ION, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2013-05-08 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
|
|
4KQ4
 | | Crystal structure of Anti-IL-17A antibody CNTO7357 | | 分子名称: | CNTO7357 heavy chain, CNTO7357 light chain, NICKEL (II) ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2013-05-14 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
|
|
4EUG
 | | Crystallographic and Enzymatic Studies of an Active Site Variant H187Q of Escherichia Coli Uracil DNA Glycosylase: Crystal Structures of Mutant H187Q and its Uracil Complex | | 分子名称: | PROTEIN (GLYCOSYLASE) | | 著者 | Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. | | 登録日 | 1998-12-27 | | 公開日 | 1999-07-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Heteronuclear NMR and crystallographic studies of wild-type and H187Q Escherichia coli uracil DNA glycosylase: electrophilic catalysis of uracil expulsion by a neutral histidine 187.
Biochemistry, 38, 1999
|
|
4KUZ
 | |
3G6A
 | |
3I2C
 | | Crystal structure of anti-IL-23 antibody CNTO4088 | | 分子名称: | CNTO4088 HEAVY CHAIN, CNTO4088 LIGHT CHAIN, GLYCEROL | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2009-06-29 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Noncanonical conformation of CDR L1 in the anti-IL-23 antibody CNTO4088.
Acta Crystallogr.,Sect.F, 66, 2010
|
|
3IFD
 | |
3I84
 | |
1CLS
 | | CROSS-LINKED HUMAN HEMOGLOBIN DEOXY | | 分子名称: | HEMOGLOBIN, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Ji, X, Fronticelli, C, Bucci, E, Gilliland, G.L. | | 登録日 | 1995-08-29 | | 公開日 | 1996-10-14 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Positive and negative cooperativities at subsequent steps of oxygenation regulate the allosteric behavior of multistate sebacylhemoglobin.
Biochemistry, 35, 1996
|
|
3I85
 | |
3G6D
 | | Crystal structure of the complex between CNTO607 Fab and IL-13 | | 分子名称: | CNTO607 Fab Heavy chain, CNTO607 Fab Light chain, Interleukin-13, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2009-02-06 | | 公開日 | 2009-04-07 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Epitope mapping of anti-interleukin-13 neutralizing antibody CNTO607.
J.Mol.Biol., 389, 2009
|
|
1WSA
 | | STRUCTURE OF L-ASPARAGINASE II PRECURSOR | | 分子名称: | ASPARAGINE AMIDOHYDROLASE | | 著者 | Lubkowski, J, Palm, G.J, Gilliland, G.L, Derst, C, Rohm, K.-H, Wlodawer, A. | | 登録日 | 1996-08-15 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase.
Eur.J.Biochem., 241, 1996
|
|
1YI7
 | | Beta-d-xylosidase (selenomethionine) XYND from Clostridium Acetobutylicum | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-xylosidase, family 43 glycosyl hydrolase, ... | | 著者 | Teplyakov, A, Fedorov, E, Gilliland, G.L, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-01-11 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of beta-xylosidase from clostridium acetobutylicum
To be Published
|
|
1Y7B
 | | BETA-D-XYLOSIDASE, A FAMILY 43 GLYCOSIDE HYDROLASE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-xylosidase, family 43 glycosyl hydrolase, ... | | 著者 | Teplyakov, A, Fedorov, E, Gilliland, G.L, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2004-12-08 | | 公開日 | 2005-01-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of beta-xylosidase from Clostridium acetobutylicum
To be Published
|
|
5W05
 | | ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10 | | 分子名称: | DI(HYDROXYETHYL)ETHER, M59 FAB HEAVY CHAIN, M59 FAB LIGHT CHAIN | | 著者 | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | | 登録日 | 2017-05-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structural insights into humanization of anti-tissue factor antibody 10H10.
MAbs, 10, 2018
|
|
5W3P
 | | ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16 | | 分子名称: | Amyloid beta A4 protein, Antibody C706 Fab HEAVY CHAIN, Antibody C706 Fab LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2017-06-08 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | A coiled conformation of amyloid-beta recognized by antibody C706.
Alzheimers Res Ther, 9, 2017
|
|
5VME
 | | Crystal structure of human IgG1 Fc K248E, T437R mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, human IgG1 Fc K248E,T437R mutant | | 著者 | Armstrong, A.A, Gilliland, G.L. | | 登録日 | 2017-04-27 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization.
MAbs, 9, 2017
|
|
5W5M
 | | Crystal structure of human IgG4-Sigma1 Fc fragment | | 分子名称: | ACETATE ION, GLYCEROL, Immunoglobulin heavy constant gamma 4, ... | | 著者 | Armstrong, A.A, Gilliland, G.L. | | 登録日 | 2017-06-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
|
|
5WK3
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CCL17 AND M116 FAB | | 分子名称: | C-C motif chemokine 17, GLYCEROL, M116 HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2017-07-24 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural insights into chemokine CCL17 recognition by antibody M116.
Biochem Biophys Rep, 13, 2018
|
|
5WK2
 | | CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, M116 HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Gilliland, G.L. | | 登録日 | 2017-07-24 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural insights into chemokine CCL17 recognition by antibody M116.
Biochem Biophys Rep, 13, 2018
|
|
5W5L
 | | Crystal structure of human IgG1-Sigma Fc fragment | | 分子名称: | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Armstrong, A.A, Gilliland, G.L. | | 登録日 | 2017-06-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
|
|
5W5N
 | | Crystal structure of human IgG4-Sigma2 Fc fragment | | 分子名称: | ACETATE ION, GLYCEROL, Immunoglobulin heavy constant gamma 4, ... | | 著者 | Armstrong, A.A, Gilliland, G.L. | | 登録日 | 2017-06-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.
Antibodies, 6, 2017
|
|
5W06
 | | HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587 | | 分子名称: | GLYCEROL, M1587 FAB HEAVY CHAIN, M1587 FAB LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | | 登録日 | 2017-05-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into humanization of anti-tissue factor antibody 10H10.
MAbs, 10, 2018
|
|
