5K7O
| MicroED structure of lysozyme at 1.8 A resolution | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7N
| MicroED structure of tau VQIVYK peptide at 1.1 A resolution | 分子名称: | VQIVYK | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7S
| MicroED structure of proteinase K at 1.6 A resolution | 分子名称: | CALCIUM ION, Proteinase K | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.6 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7P
| MicroED structure of xylanase at 2.3 A resolution | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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1RHG
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1DDT
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3CAE
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3MML
| Allophanate Hydrolase Complex from Mycobacterium smegmatis, Msmeg0435-Msmeg0436 | 分子名称: | Allophanate hydrolase subunit 1, Allophanate hydrolase subunit 2, CHLORIDE ION | 著者 | Kaufmann, M, Chernishof, I, Shin, A, Germano, D, Sawaya, M.R, Waldo, G.S, Arbing, M.A, Perry, J, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-04-20 | 公開日 | 2010-04-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of Allphanate Hydrolase Complex from M. smegmatis, Msmeg0435-Msmeg0436 To be Published
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1Z6K
| Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis | 分子名称: | Citrate Lyase beta subunit, MAGNESIUM ION, OXALOACETATE ION | 著者 | Goulding, C.W, Bowers, P.M, Segelke, B, Lekin, T, Kim, C.Y, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-03-22 | 公開日 | 2005-05-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J.Mol.Biol., 365, 2007
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5CCA
| Crystal structure of Mtb toxin | 分子名称: | Endoribonuclease MazF3 | 著者 | Cascio, D, Arbing, M, de Serrano, V, Eisenberg, D, Miallau, L, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-01 | 公開日 | 2016-09-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of Mtb toxin To Be Published
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5DUD
| Crystal structure of E. coli YbgJK | 分子名称: | YbgJ, YbgK | 著者 | Arbing, M.A, Kaufmann, M, Shin, A, Medrano-Soto, A, Cascio, D, Eisenberg, D. | 登録日 | 2015-09-18 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of E. coli YbgJK To Be Published
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1COS
| CRYSTAL STRUCTURE OF A SYNTHETIC TRIPLE-STRANDED ALPHA-HELICAL BUNDLE | 分子名称: | COILED SERINE | 著者 | Lovejoy, B, Choe, S, Cascio, D, Mcrorie, D.K, Degrado, W, Eisenberg, D. | 登録日 | 1993-01-22 | 公開日 | 1993-10-31 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a synthetic triple-stranded alpha-helical bundle. Science, 259, 1993
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4I0X
| Crystal structure of the Mycobacterum abscessus EsxEF (Mab_3112-Mab_3113) complex | 分子名称: | BETA-MERCAPTOETHANOL, ESAT-6-like protein MAB_3112, ESAT-6-like protein MAB_3113, ... | 著者 | Arbing, M.A, Chan, S, Lu, J, Kuo, E, Harris, L, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-11-19 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | 主引用文献 | Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
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1Z9W
| Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis | 分子名称: | Dihydroneopterin aldolase | 著者 | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | 登録日 | 2005-04-05 | 公開日 | 2005-04-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. J.Mol.Biol., 349, 2005
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2APQ
| Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. | 分子名称: | PHOSPHATE ION, Ribonuclease | 著者 | Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. | 登録日 | 2005-08-16 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437, 2005
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3N3E
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6E6Z
| Structure of Wild Type Human Transthyretin in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E77
| Structure of Human Transthyretin Asp38Ala Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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3SGS
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6E70
| Structure of Wild Type Human Transthyretin in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, CALCIUM ION, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E76
| Structure of Human Transthyretin Asp38Ala/Thr119Met Mutant | 分子名称: | ACETATE ION, GLYCEROL, SULFATE ION, ... | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E72
| Structure of Human Transthyretin Val30Met Mutant in Complex with Tafamidis | 分子名称: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E71
| Structure of Human Transthyretin Val30Met/Thr119Met Mutant | 分子名称: | DI(HYDROXYETHYL)ETHER, Transthyretin | 著者 | Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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6E78
| Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal | 分子名称: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | 著者 | Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. | 登録日 | 2018-07-25 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Structural Variants of Transthyretin To Be Published
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4E0K
| Crystal Structure of the amyloid-fibril forming peptide KDWSFY derived from human Beta 2 Microglobulin (58-63) | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Amyloidogenic peptide segment KDWSFY, SODIUM ION | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2012-12-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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