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7SL6
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BU of 7sl6 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL3
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BU of 7sl3 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL4
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BU of 7sl4 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL7
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BU of 7sl7 by Molmil
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R)
分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ...
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL1
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BU of 7sl1 by Molmil
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STI
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BU of 7sti by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STJ
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BU of 7stj by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STK
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BU of 7stk by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STH
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BU of 7sth by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
8OYU
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BU of 8oyu by Molmil
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ...
著者Weckener, M, Naismith, J.H, Owens, R.J.
登録日2023-05-05
公開日2024-05-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
7F8L
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BU of 7f8l by Molmil
Crystal structure of Bat coronavirus RaTG13 ORF8 accessory protein
分子名称: CALCIUM ION, Nonstructural protein NS8
著者Chen, X, Zhou, Z, Chen, S.
登録日2021-07-02
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.762 Å)
主引用文献Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
7F5F
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BU of 7f5f by Molmil
SARS-CoV-2 ORF8 S84
分子名称: CALCIUM ION, ORF8 protein
著者Chen, S, Zhou, Z, Chen, X.
登録日2021-06-22
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
7D99
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BU of 7d99 by Molmil
human potassium-chloride co-transporter KCC4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, POTASSIUM ION, ...
著者Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J.
登録日2020-10-12
公開日2020-12-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures and an activation mechanism of human potassium-chloride cotransporters.
Sci Adv, 6, 2020
7D90
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BU of 7d90 by Molmil
human potassium-chloride co-transporter KCC3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 3
著者Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J.
登録日2020-10-12
公開日2020-12-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures and an activation mechanism of human potassium-chloride cotransporters.
Sci Adv, 6, 2020
7D8Z
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BU of 7d8z by Molmil
human potassium-chloride co-transporter KCC2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, potassium-chloride cotransporter 2
著者Xie, Y, Chang, S, Zhao, C, Ye, S, Guo, J.
登録日2020-10-11
公開日2020-12-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures and an activation mechanism of human potassium-chloride cotransporters.
Sci Adv, 6, 2020
4L3Q
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BU of 4l3q by Molmil
Crystal structure of glucokinase-activator complex
分子名称: 6-{3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]phenyl}pyridin-2(1H)-one, Glucokinase, alpha-D-glucopyranose
著者Gajiwala, K.S, Filipski, K.J.
登録日2013-06-06
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif.
Bioorg.Med.Chem.Lett., 23, 2013
6IIC
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BU of 6iic by Molmil
CryoEM structure of Mud Crab Dicistrovirus
分子名称: VP1 of Mud crab dicistrovirus, VP2 of Mud crab dicistrovirus, VP3 of Mud crab dicistrovirus, ...
著者Zhang, Q, Gao, Y.
登録日2018-10-04
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-electron Microscopy Structures of Novel Viruses from Mud CrabScylla paramamosainwith Multiple Infections.
J. Virol., 93, 2019
6BFG
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BU of 6bfg by Molmil
Crystal structure of monotopic membrane protein (S)-mandelate dehydrogenase
分子名称: (S)-mandelate dehydrogenase, 1,2-ETHANEDIOL, CITRIC ACID, ...
著者Sukumar, N.
登録日2017-10-26
公開日2018-08-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the monotopic membrane protein (S)-mandelate dehydrogenase at 2.2 angstrom resolution.
Biochimie, 154, 2018
6IZL
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BU of 6izl by Molmil
Cryo-EM structure of Mud crab tombus-like virus at 3.3 Angstroms resolution
分子名称: mud crab tombus-like virus
著者Zhang, Q, Gao, Y.
登録日2018-12-19
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-electron Microscopy Structures of Novel Viruses from Mud CrabScylla paramamosainwith Multiple Infections.
J. Virol., 93, 2019
3TB3
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BU of 3tb3 by Molmil
Crystal structure of the UCH domain of UCH-L5 with 6 residues deleted
分子名称: CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5
著者Zhou, Z.R, Zha, M, Zhou, J, Hu, H.Y.
登録日2011-08-05
公開日2012-02-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains.
Biochem.J., 441, 2012
6JO7
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BU of 6jo7 by Molmil
Crystal structure of mouse MXRA8
分子名称: Matrix remodeling-associated protein 8
著者Song, H, Zhao, Z, Qi, J, Gao, F, Gao, G.F.
登録日2019-03-20
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.
Cell, 177, 2019
6BRR
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BU of 6brr by Molmil
Crystal structure of DNMT3A (R836A)-DNMT3L in complex with DNA containing two CpG sites
分子名称: DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
著者Zhang, Z.M, Song, J.
登録日2017-11-30
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
6JJI
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BU of 6jji by Molmil
Crystal structure of a two-quartet RNA parallel G-quadruplex complexed with the porphyrin TMPyP4 (1:1)
分子名称: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, POTASSIUM ION, RNA (5'-R(*GP*GP*CP*UP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3')
著者Zhang, Y.S, Parkinson, G.N, Wei, D.G.
登録日2019-02-25
公開日2020-02-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Res., 48, 2020
8WKX
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BU of 8wkx by Molmil
Cryo-EM structure of DSR2
分子名称: SIR2-like domain-containing protein
著者Gao, A, Huang, J, Zhu, K.
登録日2023-09-28
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024
8WKS
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BU of 8wks by Molmil
Cryo-EM structure of DSR2-TUBE complex
分子名称: SIR2-like domain-containing protein, TUBE
著者Gao, A, Huang, J, Zhu, K.
登録日2023-09-28
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion.
Nat Commun, 15, 2024

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