4HR3
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4F3W
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4R0L
| Anti-canine CD28 antibody, 1C6, bound canine CD28 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gewe, M.M, Strong, R.K. | 登録日 | 2014-07-31 | 公開日 | 2015-07-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Anti-CD28 Antibody-Initiated Cytokine Storm in Canines. Transplant Direct, 1, 2015
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4I1Y
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7LXI
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5IFU
| Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with Glyburide | 分子名称: | 1,2-ETHANEDIOL, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, CHLORIDE ION, ... | 著者 | Dranow, D.M, Hewitt, S.N, Abendroth, J, Structural Genomics Consortium (SGC) | 登録日 | 2016-02-26 | 公開日 | 2016-11-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infect Dis, 3, 2017
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4P9A
| X-ray Crystal Structure of PA protein from Influenza strain H7N9 | 分子名称: | GLYCEROL, Polymerase PA | 著者 | Fairman, J.W, Moen, S.O, Clifton, M.C, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2014-04-02 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1999 Å) | 主引用文献 | Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1. Sci Rep, 4, 2014
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7MYQ
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7MYS
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7MMZ
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7MHV
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4PFS
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4O2D
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7S5E
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7S87
| Crystal Structure of Dihydroorotate dehydrogenase from Plasmodium falciparum in complex with Orotate, FMN, and inhibitor NCGC00600348-01 | 分子名称: | (4R)-3-methyl-5-[(4R)-4-methyl-3,4-dihydroisoquinolin-2(1H)-yl]thieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2021-09-17 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structure of Dihydroorotate dehydrogenase from Plasmodium falciparum in complex with Orotate, FMN, and inhibitor NCGC00600348-01 To Be Published
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7SBC
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7RZO
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7SIQ
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4ED4
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7N4D
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7RY7
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7MI0
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6SLG
| HUMAN ERK2 WITH ERK1/2 INHIBITOR, AZD0364. | 分子名称: | (6~{R})-7-[[3,4-bis(fluoranyl)phenyl]methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one, 1,2-ETHANEDIOL, ERK-tide, ... | 著者 | Breed, J, Phillips, C. | 登録日 | 2019-08-19 | 公開日 | 2019-11-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Discovery of a Potent and Selective Oral Inhibitor of ERK1/2 (AZD0364) That Is Efficacious in Both Monotherapy and Combination Therapy in Models of Nonsmall Cell Lung Cancer (NSCLC). J.Med.Chem., 62, 2019
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4EGE
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4EMD
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