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8YPU
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BU of 8ypu by Molmil
Cryo-EM structure of ButCD complex
分子名称: Membrane protein, SusC/RagA family TonB-linked outer membrane protein
著者Xu, J.H, Chen, Z, Gao, X.
登録日2024-03-18
公開日2024-09-25
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues.
Nat Commun, 15, 2024
9C10
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BU of 9c10 by Molmil
AMG 193, a clinical stage MTA-cooperative PRMT5 inhibitor, drives anti-tumor activity preclinically and in patients with MTAP-deleted cancers
分子名称: (4-amino-1,3-dihydrofuro[3,4-c][1,7]naphthyridin-8-yl){(3S)-3-[4-(trifluoromethyl)phenyl]morpholin-4-yl}methanone, 5'-DEOXY-5'-METHYLTHIOADENOSINE, DIMETHYL SULFOXIDE, ...
著者Ghimire-Rijal, S, Mukund, S.
登録日2024-05-28
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients With MTAP-Deleted Cancers.
Cancer Discov, 2024
8YPT
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BU of 8ypt by Molmil
Cryo-EM structure of BfUbb-ButCD complex
分子名称: Membrane protein, TonB-linked outer membrane protein, Ubiquitin-like protein
著者Xu, J.H, Chen, Z, Gao, X.
登録日2024-03-18
公開日2024-09-25
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues.
Nat Commun, 15, 2024
6LP9
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BU of 6lp9 by Molmil
the protein of cat virus
分子名称: nsp1 protein
著者Shen, Z, Peng, G.Q.
登録日2020-01-09
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
Viruses, 12, 2020
9C0O
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BU of 9c0o by Molmil
Crystal structure of DmCfp1 PHD finger bound to H3K4me3
分子名称: CXXC-type zinc finger protein 1, DIMETHYL SULFOXIDE, Histone H3.3C, ...
著者Gregoire, S, Couture, J.F.
登録日2024-05-27
公開日2024-07-03
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural insights into an atypical histone binding mechanism by a PHD finger.
Structure, 32, 2024
8IOF
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BU of 8iof by Molmil
Crystal structure of N-methyl-Cis-4-hydroxy-D-proline dehydratase in Clostridium sp. FS41
分子名称: (2R,4R)-1-methyl-4-hydroxyl-pyrrolidine-2-carboxylic acid, Benzylsuccinate synthase alpha subunit
著者Jiang, L, Zhang, Y.
登録日2023-03-11
公開日2024-03-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Glycyl Radical Enzymes Catalyzing the Dehydration of Two Isomers of N-Methyl-4-hydroxyproline
Acs Catalysis, 14, 2024
3MF5
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BU of 3mf5 by Molmil
Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
分子名称: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase
著者Harris, S.F, Tavares, G, Ghate, M.
登録日2010-04-01
公開日2010-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
1T0P
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BU of 1t0p by Molmil
Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, Intercellular adhesion molecule-3, ...
著者Song, G, Yang, Y.T, Liu, J.H, Shimaoko, M, Springer, T.A, Wang, J.H.
登録日2004-04-12
公開日2005-03-08
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.
Proc.Natl.Acad.Sci.Usa, 102, 2005
4LSU
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BU of 4lsu by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSV
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BU of 4lsv by Molmil
Crystal structure of broadly and potently neutralizing antibody 3BNC117 in complex with HIV-1 clade C C1086 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEAVY CHAIN OF ANTIBODY 3BNC117, IMIDAZOLE, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSS
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BU of 4lss by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY VRC01, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSP
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BU of 4lsp by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSR
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BU of 4lsr by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E stran 93TH057 gp120 with LOOP D and Loop V5 from clade A strain KER_2018_11
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120 WITH LOOP D AND V5 FROM STRAIN ker_2018_11, HEAVY CHAIN OF ANTIBODY VRC-CH31, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
4LSQ
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BU of 4lsq by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057 with LOOP D and Loop V5 from clade A strain 3415_v1_c1
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-07-23
公開日2013-08-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
6WXL
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BU of 6wxl by Molmil
Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer
分子名称: 1D12 Light chain, 1D21 Heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorman, J, Kwong, P.D.
登録日2020-05-11
公開日2021-06-09
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.
Structure, 2022
6LKG
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BU of 6lkg by Molmil
two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ...
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKK
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BU of 6lkk by Molmil
Two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKL
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BU of 6lkl by Molmil
Two-component system protein mediate signal transduction
分子名称: ABC transporter, solute-binding protein, MALONIC ACID
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.213 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKI
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BU of 6lki by Molmil
Two-component system protein mediate signal transduction
分子名称: ABC transporter, solute-binding protein, MALONIC ACID, ...
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.781 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LKJ
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BU of 6lkj by Molmil
Two-component system protein mediate signal transduction
分子名称: 6-O-phosphono-beta-D-galactopyranose, ABC transporter, solute-binding protein
著者Wang, M, Tao, Y.
登録日2019-12-19
公開日2020-12-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Interface switch mediates signal transmission in a two-component system.
Proc.Natl.Acad.Sci.USA, 117, 2020
3U4B
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BU of 3u4b by Molmil
CH04H/CH02L Fab P4
分子名称: CH02 Light chain, CH04 Heavy chain
著者Pancera, M, Louder, R, Mclellan, J.S, KWong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.893 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U36
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BU of 3u36 by Molmil
Crystal Structure of PG9 Fab
分子名称: PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
著者McLellan, J.S, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.281 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
5W0C
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BU of 5w0c by Molmil
Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex
分子名称: Cytochrome P450 2C9, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Johnson, E.F, Hsu, M.-H.
登録日2017-05-30
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
Angew. Chem. Int. Ed. Engl., 56, 2017
3U4E
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BU of 3u4e by Molmil
Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain CAP45
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG9 Heavy Chain, PG9 Light Chain, ...
著者Gorman, J, McLellan, J, Pancera, M, Kwong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.185 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U2S
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BU of 3u2s by Molmil
Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者McLellan, J.S, Pancera, M, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011

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