7EMA
| Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I | 分子名称: | Beta-2-microglobulin, Leucocyte antigen, TYR-SER-SER-ASP-VAL-THR-THR-LEU-VAL | 著者 | Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J. | 登録日 | 2021-04-13 | 公開日 | 2021-12-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I. J.Virol., 96, 2022
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4MTL
| Human Methyltransferase-Like Protein 21C | 分子名称: | Protein-lysine methyltransferase METTL21C, S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION | 著者 | Hong, B.S, Tempel, W, Dong, A, Li, Y, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2013-09-19 | 公開日 | 2013-10-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Human Methyltransferase-Like Protein 21C To be Published
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7EM9
| Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I | 分子名称: | Beta-2-microglobulin, Leucocyte antigen, SER-LEU-ASP-GLU-TYR-SER-SER-ASP-VAL | 著者 | Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J. | 登録日 | 2021-04-13 | 公開日 | 2021-12-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I. J.Virol., 96, 2022
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4Q2Z
| Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate | 分子名称: | Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody | 著者 | Navis, M, Tran, K, Bale, S, Phad, G, Guenaga, J, Wilson, R, Soldemo, M, McKee, K, Sundling, C, Mascola, J, Li, Y, Wyatt, R.T, Hedestam, G.B.K. | 登録日 | 2014-04-10 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization. Plos Pathog., 10, 2014
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4PWY
| Crystal structure of a Calmodulin-lysine N-methyltransferase fragment | 分子名称: | Calmodulin-lysine N-methyltransferase, GLYCEROL, MALONATE ION, ... | 著者 | Tempel, W, Hong, B.S, Walker, J.R, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2014-03-21 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a Calmodulin-lysine N-methyltransferase fragment TO BE PUBLISHED
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4PXW
| Crystal structure of human DCAF1 WD40 repeats (Q1250L) | 分子名称: | Protein VPRBP, UNKNOWN ATOM OR ION | 著者 | Xu, C, Tempel, W, He, H, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-03-25 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of human DCAF1 WD40 repeats (Q1250L) TO BE PUBLISHED
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8EQZ
| Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog T0-C6 | 分子名称: | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-hexylbenzenesulfonamide, Nuclear receptor subfamily 1 group I member 2 | 著者 | Huber, A.D, Poudel, S, Seetharaman, J, Miller, D.J, Lin, W, Li, Y, Chen, T. | 登録日 | 2022-10-11 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein. Proc.Natl.Acad.Sci.USA, 120, 2023
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8FPE
| Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog T0-BP | 分子名称: | N-[([1,1'-biphenyl]-4-yl)methyl]-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide, Nuclear receptor subfamily 1 group I member 2 | 著者 | Huber, A.D, Poudel, S, Seetharaman, J, Miller, D.J, Lin, W, Li, Y, Chen, T. | 登録日 | 2023-01-04 | 公開日 | 2023-03-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein. Proc.Natl.Acad.Sci.USA, 120, 2023
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6K61
| Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. | 登録日 | 2019-05-31 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | 主引用文献 | Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria. Nat.Plants, 5, 2019
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7CZ0
| Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb92) | 分子名称: | ACETATE ION, CACODYLATE ION, CACODYLIC ACID, ... | 著者 | Cai, H, Yao, H, Li, T, Hutter, C, Tang, Y, Li, Y, Seeger, M, Li, D. | 登録日 | 2020-09-06 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | An improved fluorescent protein tag and its nanobodies for membrane protein expression, stability assay, and purification To Be Published
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5FRR
| Structure of the Pds5-Scc1 complex and implications for cohesin function | 分子名称: | SISTER CHROMATID COHESION PROTEIN PDS5 | 著者 | Muir, K.W, Kschonsak, M, Li, Y, Metz, J, Haering, C.H, Panne, D. | 登録日 | 2015-12-22 | 公開日 | 2016-03-02 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (5.8 Å) | 主引用文献 | Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function Cell Rep., 14, 2016
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5H4I
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7WMO
| A novel chemical derivative(92) of THRB agonist | 分子名称: | 2-[[1-ethoxy-7-[4-(3-fluoranyl-5-methoxy-phenyl)carbonyl-2,6-dimethyl-phenoxy]-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-15 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WML
| A novel chemical derivative(85) of THRB agonist | 分子名称: | 2-[[7-[4-(3,5-dimethylphenyl)carbonyl-2,6-dimethyl-phenoxy]-1-ethoxy-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-15 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WMJ
| A novel chemical derivative(71) of THRB agonist | 分子名称: | 2-[[7-[2,6-dimethyl-4-(phenylcarbonyl)phenoxy]-1-methoxy-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-14 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WMH
| A novel chemical derivative(56) of THRB agonist | 分子名称: | 2-[[1-methoxy-4-oxidanyl-7-(4-phenylphenoxy)isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-14 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WMG
| A novel chemical derivative(52) of THRB agonist | 分子名称: | 2-[[1-methoxy-4-oxidanyl-7-(4-phenoxyphenoxy)isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-14 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WLX
| A novel chemical derivative(53) of THRB agonist | 分子名称: | 2-[[1-methoxy-4-oxidanyl-7-[4-(phenylmethyl)phenoxy]isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-14 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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7WMN
| A novel chemical derivative(89) of THRB agonist | 分子名称: | 2-[[7-[2,6-dimethyl-4-(3-methylphenyl)carbonyl-phenoxy]-1-methoxy-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2 | 著者 | Yao, B.Q, Li, Y. | 登録日 | 2022-01-15 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist. J.Med.Chem., 65, 2022
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4IJ8
| Crystal structure of the complex of SETD8 with SAM | 分子名称: | N-lysine methyltransferase SETD8, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, ... | 著者 | Yu, W, Tempel, W, Li, Y, El Bakkouri, M, Shapira, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | 登録日 | 2012-12-21 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the complex of SETD8 with SAM To be Published
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8TTF
| NorA double mutant - E222QD307N at pH 7.5 | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTH
| NorA single mutant - D307N at pH 7.5 | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTE
| Protonated state of NorA at pH 5.0 | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TTG
| NorA single mutant - E222Q at pH 7.5 | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | 登録日 | 2023-08-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA. Nat Commun, 15, 2024
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8TS0
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