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4K84
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BU of 4k84 by Molmil
Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 16:0 ceramide-1-phosphate (16:0-C1P)
分子名称: (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-04-17
公開日2013-07-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4KBR
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Crystal structure of mouse Ceramide-1-phosphate transfer protein (apo-form)
分子名称: Glycolipid transfer protein domain-containing protein 1, PHOSPHATE ION
著者Simanshu, D.K, Brown, R.E, Patel, D.J.
登録日2013-04-23
公開日2013-07-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.547 Å)
主引用文献Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
4QNZ
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BU of 4qnz by Molmil
Crystal structure of rhomboid intramembrane protease GlpG F146I in complex with peptide derived inhibitor Ac-FATA-cmk
分子名称: ACE-PHE-ALA-THR-ALA-0QE, CHLORIDE ION, Rhomboid protease GlpG, ...
著者Zoll, S, Strisovsky, K.
登録日2014-06-19
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.
Embo J., 33, 2014
4FEH
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BU of 4feh by Molmil
Mycobacterium tuberculosis DprE1 - hexagonal crystal form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, oxidoreductase DprE1
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2012-05-30
公開日2012-07-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.035 Å)
主引用文献Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Proc.Natl.Acad.Sci.USA, 109, 2012
4QO0
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BU of 4qo0 by Molmil
Crystal structure of rhomboid intramembrane protease GlpG in complex with peptide derived inhibitor Ac-FATA-cmk
分子名称: ACE-PHE-ALA-THR-ALA-0QE, CHLORIDE ION, Rhomboid protease GlpG, ...
著者Zoll, S, Strisovsky, K.
登録日2014-06-19
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.
Embo J., 33, 2014
4IHL
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BU of 4ihl by Molmil
Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A
分子名称: (1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1 1-tetraoxatricyclo[6.2.1.0~1,6~]undec-4-yl}oxy)-1-(methoxymethyl)-4,9a-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8,9,9a-de cahydrodicyclopenta[a,d][8]annulene-1,5-diol, 14-3-3 protein zeta/delta, POTASSIUM ION, ...
著者Molzan, M, Ottmann, C.
登録日2012-12-19
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers.
Acs Chem.Biol., 8, 2013
4MGS
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BU of 4mgs by Molmil
BiXyn10A CBM1 APO
分子名称: Putative glycosyl hydrolase family 10
著者Chekan, J.R, Nair, S.K.
登録日2013-08-28
公開日2014-08-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Xylan utilization in human gut commensal bacteria is orchestrated by unique modular organization of polysaccharide-degrading enzymes.
Proc.Natl.Acad.Sci.USA, 111, 2014
3OKA
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BU of 3oka by Molmil
Crystal structure of Corynebacterium glutamicum PimB' in complex with GDP-Man (triclinic crystal form)
分子名称: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ...
著者Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K.
登録日2010-08-24
公開日2010-09-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
3OKC
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Crystal structure of Corynebacterium glutamicum PimB' bound to GDP (orthorhombic crystal form)
分子名称: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE
著者Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K.
登録日2010-08-24
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
2DY2
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BU of 2dy2 by Molmil
Nitrite reductase pH 6.0
分子名称: COPPER (II) ION, Copper-containing nitrite reductase
著者Jacobson, F.
登録日2006-09-05
公開日2006-12-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献pH Dependence of Copper Geometry, Reduction Potential, and Nitrite Affinity in Nitrite Reductase
J.Biol.Chem., 282, 2007
3CQ5
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BU of 3cq5 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum in complex with PMP
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Histidinol-phosphate aminotransferase, SULFATE ION, ...
著者Sandalova, T, Marienhagen, J, Schneider, G.
登録日2008-04-02
公開日2008-07-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
3CQ4
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BU of 3cq4 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum
分子名称: ACETATE ION, Histidinol-phosphate aminotransferase
著者Sandalova, T, Marienhagen, J, Schneider, G.
登録日2008-04-02
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
2PSZ
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BU of 2psz by Molmil
Structure of the PTP-like Phytase expressed by Selenomonas ruminantium at low ionic strength
分子名称: GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase
著者Gruninger, R.J, Selinger, L.B, Mosimann, S.C.
登録日2007-05-07
公開日2008-05-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr.
Febs J., 275, 2008
3B9X
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BU of 3b9x by Molmil
Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK in complex with inosine
分子名称: CALCIUM ION, INOSINE, Pyrimidine-specific ribonucleoside hydrolase rihB, ...
著者Iovane, E, Degano, M.
登録日2007-11-07
公開日2008-04-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for substrate specificity in group I nucleoside hydrolases
Biochemistry, 47, 2008
1Y26
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BU of 1y26 by Molmil
A-riboswitch-adenine complex
分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus A-riboswitch
著者Serganov, A, Yuan, Y.R, Patel, D.J.
登録日2004-11-20
公開日2004-12-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs
Chem.Biol., 11, 2004
2PT0
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BU of 2pt0 by Molmil
Structure of Selenomonas ruminantium PTP-like phytase with the active site cysteine oxidized to cysteine-sulfonic acid
分子名称: GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase
著者Gruninger, R.J, Selinger, L.B, Mosimann, S.C.
登録日2007-05-07
公開日2008-05-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr.
Febs J., 275, 2008
8VTT
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BU of 8vtt by Molmil
Meis1 homeobox domain bound to neomycin fragment
分子名称: Homeobox protein Meis1, RIBOSTAMYCIN, SULFATE ION
著者Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N, Sadek, H.A.
登録日2024-01-27
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals
to be published
8VTS
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BU of 8vts by Molmil
Meis1 homeobox domain bound to paromomycin fragment
分子名称: 1,2-ETHANEDIOL, Homeobox protein Meis1, ISOPROPYL ALCOHOL, ...
著者Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N.
登録日2024-01-27
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals
to be published
3CQ6
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BU of 3cq6 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum holo-form (PLP covalently bound )
分子名称: Histidinol-phosphate aminotransferase, PHOSPHATE ION
著者Sandalova, T, Marienhagen, J, Schneider, G.
登録日2008-04-02
公開日2008-07-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
5T1S
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BU of 5t1s by Molmil
Irak4 kinase - compound 1 co-structure
分子名称: 5-[3-(3,5-dimethylphenyl)-4-[4-(methylamino)butyl]quinolin-6-yl]pyridin-3-ol, Interleukin-1 receptor-associated kinase 4
著者Fischmann, T.O.
登録日2016-08-22
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.
Bioorg. Med. Chem. Lett., 27, 2017
5T1T
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BU of 5t1t by Molmil
Irak4 kinase - compound 1 co-structure
分子名称: Interleukin-1 receptor-associated kinase 4, ~{N},~{N}-dimethyl-4-(6-nitroquinazolin-4-yl)oxy-cyclohexan-1-amine
著者Fischmann, T.O.
登録日2016-08-22
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.
Bioorg. Med. Chem. Lett., 27, 2017
3PTY
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BU of 3pty by Molmil
Crystal structure of the C-terminal extracellular domain of Mycobacterium tuberculosis EmbC
分子名称: Arabinosyltransferase C, CALCIUM ION, PHOSPHATE ION, ...
著者Alderwick, L.J, Besra, G.S, Futterer, K.
登録日2010-12-03
公開日2010-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module.
Plos Pathog., 7, 2011
3OKP
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BU of 3okp by Molmil
Crystal structure of Corynebacterium glutamicum PimB' bound to GDP-Man (orthorhombic crystal form)
分子名称: GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE
著者Batt, S.M, Jabeen, T, Besra, G.S, Futterer, K.
登録日2010-08-25
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
J.Biol.Chem., 285, 2010
3E4H
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BU of 3e4h by Molmil
Crystal structure of the cyclotide varv F
分子名称: Varv peptide F,Varv peptide F
著者Hu, S.H.
登録日2008-08-11
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold
J.Biol.Chem., 284, 2009
3EIG
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Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase
分子名称: CADMIUM ION, Dihydrofolate reductase, METHOTREXATE, ...
著者Yachnin, B.J, Berghuis, A.M.
登録日2008-09-15
公開日2009-05-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance.
J.Biol.Chem., 284, 2009

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