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7DU1
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Crystal structure of VIM-2 MBL in complex with 1-propyl-1H-imidazole-2-carboxylic acid
分子名称: 1-propylimidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Yan, Y.-H, Li, G.-B.
登録日2021-01-07
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DUE
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BU of 7due by Molmil
Crystal structure of VIM-2 MBL in complex with (R)-1-(sec-butyl)-1H-imidazole-2-carboxylic acid
分子名称: 1-[(2~{R})-butan-2-yl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-08
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DUB
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BU of 7dub by Molmil
Crystal structure of VIM-2 MBL in complex with 1-isopropyl-1H-imidazole-2-carboxylic acid
分子名称: 1-propan-2-ylimidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-08
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DUY
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BU of 7duy by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(2-(1H-1,2,3-triazol-1-yl)ethyl)-1H-imidazole-2-carboxylic acid
分子名称: 1-[2-(1,2,3-triazol-1-yl)ethyl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-12
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DV0
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BU of 7dv0 by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(4-(trifluoromethyl)benzyl)-1H-imidazole-2-carboxylic acid
分子名称: 1-[[4-(trifluoromethyl)phenyl]methyl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, GLYCEROL, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-12
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DUX
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BU of 7dux by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-1H-imidazole-2-carboxylic acid
分子名称: 1-but-3-enylimidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, GLYCEROL, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-12
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DV1
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BU of 7dv1 by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(4-hydroxybenzyl)-1H-imidazole-2-carboxylic acid
分子名称: 1-[(4-hydroxyphenyl)methyl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-12
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.966 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DUZ
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BU of 7duz by Molmil
Crystal structure of VIM-2 MBL in complex with 1-cyclobutyl-1H-imidazole-2-carboxylic acid
分子名称: 1-cyclobutylimidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ...
著者Li, G.-B, Yan, Y.-H.
登録日2021-01-12
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
2QJ0
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BU of 2qj0 by Molmil
Structure of the yeast U-box-containing ubiquitin ligase Ufd2p
分子名称: Ubiquitin conjugation factor E4
著者Tu, D, Brunger, A.T.
登録日2007-07-06
公開日2007-09-18
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Inaugural Article: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7MJ9
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BU of 7mj9 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived mutant IGFBPL1 peptide
分子名称: Beta-2-microglobulin, Insulin-like growth factor-binding protein-like 1 altered peptide, MHC class I antigen
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7MJ6
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BU of 7mj6 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7MJ7
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BU of 7mj7 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7MJA
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BU of 7mja by Molmil
HLA-A*24:02 bound to Neuroblastoma derived PHOX2B peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
7MJ8
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BU of 7mj8 by Molmil
HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ...
著者Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G.
登録日2021-04-19
公開日2021-08-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Nature, 599, 2021
5XTZ
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BU of 5xtz by Molmil
Crystal structure of GAS41 YEATS bound to H3K27ac peptide
分子名称: ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4
著者Li, H.T, Zhao, D.
登録日2017-06-21
公開日2018-06-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity.
Cell Discov, 4, 2018
2QIZ
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BU of 2qiz by Molmil
Structure of the yeast U-box-containing ubiquitin ligase Ufd2p
分子名称: POTASSIUM ION, Ubiquitin conjugation factor E4
著者Tu, D, Brunger, A.T.
登録日2007-07-06
公開日2007-09-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Inaugural Article: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4PQ6
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BU of 4pq6 by Molmil
A sperm whale myoglobin single mutant L29E Mb with native His93 coordination
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Ying-Wu, L, Xiang-shi, T, Wei, L.
登録日2014-02-28
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Regulating the coordination state of a heme protein by a designed distal hydrogen-bonding network.
ChemistryOpen, 4, 2015
7YQE
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BU of 7yqe by Molmil
Structure of human SRC regulatory domains in complex with the C-terminal PRRP motifs of GPR54.
分子名称: Proto-oncogene tyrosine-protein kinase Src,KiSS-1 receptor
著者Song, G, Xu, S.
登録日2022-08-06
公開日2023-08-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src.
Nat Commun, 15, 2024
4PQC
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BU of 4pqc by Molmil
A sperm whale myoglobin single mutant F43H Mb with native His93 coordination
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Ying-wu, L, Xiang-shi, T, Wei, L.
登録日2014-03-02
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.503 Å)
主引用文献Regulating the coordination state of a heme protein by a designed distal hydrogen-bonding network.
ChemistryOpen, 4, 2015
7NAM
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BU of 7nam by Molmil
LRP6_E1 in complex with Lr-EET-3.5
分子名称: Low-density lipoprotein receptor-related protein 6, SODIUM ION, Trypsin inhibitor 2, ...
著者Hansen, S, Hannoush, R.N.
登録日2021-06-21
公開日2022-06-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Directed evolution identifies high-affinity cystine-knot peptide agonists and antagonists of Wnt/ beta-catenin signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
3OG4
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BU of 3og4 by Molmil
The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 28 receptor, alpha (Interferon, ...
著者Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A.
登録日2010-08-16
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1.
J.Mol.Biol., 404, 2010
7O52
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BU of 7o52 by Molmil
CD22 d6-d7 in complex with Fab m971
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD22 d6-d7 Ig domains, GLYCEROL, ...
著者Ereno-Orbea, J, Sicard, T, Julien, J.P.
登録日2021-04-07
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.
J.Biol.Chem., 297, 2021
7O4Y
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m971 Fab in complex with anti-Kappa VHH domain
分子名称: Anti-Kappa VHH domain, m971 Fab heavy chain, m971 Fab light chain
著者Ereno-Orbea, J, Sicard, T, Julien, J.P.
登録日2021-04-07
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.
J.Biol.Chem., 297, 2021
4PQB
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BU of 4pqb by Molmil
A sperm whale myoglobin double mutant L29E/F43H Mb with a non-native bis-His (His64/His93) coordination
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Ying-wu, L, Xiang-shi, T, Wei, L.
登録日2014-03-01
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.942 Å)
主引用文献Regulating the coordination state of a heme protein by a designed distal hydrogen-bonding network.
ChemistryOpen, 4, 2015
7ESX
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Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wPip
分子名称: Bacteria factor 1
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-05-12
公開日2021-11-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and mechanistic insights into the complexes formed by Wolbachia cytoplasmic incompatibility factors.
Proc.Natl.Acad.Sci.USA, 118, 2021

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