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4HAC
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BU of 4hac by Molmil
Crystal Structure of the Mevalonate Kinase from an Archaeon Methanosarcina mazei
分子名称: MAGNESIUM ION, Mevalonate kinase
著者Zhuang, N, Lee, K.H.
登録日2012-09-26
公開日2012-12-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystallization and preliminary X-ray diffraction analysis of mevalonate kinase from Methanosarcina mazei.
Acta Crystallogr.,Sect.F, 68, 2012
3EBJ
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BU of 3ebj by Molmil
Crystal structure of an avian influenza virus protein
分子名称: MAGNESIUM ION, Polymerase acidic protein
著者Yuan, P, Bartlam, M, Lou, Z, Chen, S, Rao, Z, Liu, Y.
登録日2008-08-27
公開日2009-02-10
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
Nature, 458, 2009
6ISQ
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BU of 6isq by Molmil
structure of Lipase mutant with oxided Cys-His-Asp catalytic triad
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ISOPROPYL ALCOHOL, ...
著者Cen, Y.X, Zhou, J.H, Wu, Q.
登録日2018-11-18
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
6ISR
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BU of 6isr by Molmil
structure of lipase mutant with Cys-His-Asp catalytic triad
分子名称: DI(HYDROXYETHYL)ETHER, Lipase B, NICKEL (II) ION, ...
著者Cen, Y.X, Zhou, J.H, Wu, Q.
登録日2018-11-18
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
6ISP
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BU of 6isp by Molmil
structure of Candida antarctica Lipase B mutant
分子名称: CALCIUM ION, Lipase B, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE
著者Cen, Y.X, Zhou, J.H, Wu, Q.
登録日2018-11-18
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.
Nat Commun, 10, 2019
7DUU
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BU of 7duu by Molmil
Crystal structure of HLA molecule with an KIR receptor
分子名称: Beta-2-microglobulin, Killer cell immunoglobulin-like receptor 2DS2, LEU-ASN-PRO-SER-VAL-ALA-ALA-THR-LEU, ...
著者Yang, Y, Yin, L.
登録日2021-01-11
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Activating receptor KIR2DS2 bound to HLA-C1 reveals the novel recognition features of activating receptor.
Immunology, 165, 2022
8F8Y
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BU of 8f8y by Molmil
PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8F8Z
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BU of 8f8z by Molmil
PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
5HCV
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BU of 5hcv by Molmil
Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists
分子名称: 6-[(~{E})-(3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene)methyl]-4~{H}-1,4-benzoxazin-3-one, CHLORIDE ION, Mineralocorticoid receptor
著者Chen, G, McKeever, B.M.
登録日2016-01-04
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.
Bioorg.Med.Chem., 24, 2016
6LPD
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BU of 6lpd by Molmil
Phascolosoma esculenta
分子名称: FE (II) ION, FE (III) ION, Ferritin
著者Su, X.R, Ming, T.H.
登録日2020-01-09
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta.
Febs Open Bio, 11, 2021
6LP5
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BU of 6lp5 by Molmil
Structure of Sinonovacula constricta ferritin
分子名称: FE (II) ION, FE (III) ION, Ferritin, ...
著者Su, X.R, Ming, T.H, Su, C.
登録日2020-01-08
公開日2020-04-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystallographic characterization of ferritin from Sinonovacula constricta.
Biochem.Biophys.Res.Commun., 524, 2020
6LPE
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BU of 6lpe by Molmil
Phascolosoma esculenta ferritin
分子名称: Ferritin, MAGNESIUM ION, SULFATE ION
著者Su, X.R, Ming, T.H.
登録日2020-01-10
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta.
Febs Open Bio, 11, 2021
6MBD
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BU of 6mbd by Molmil
Human Mcl-1 in complex with the designed peptide dM1
分子名称: Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION, dM1
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6MBC
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BU of 6mbc by Molmil
Human Bfl-1 in complex with the designed peptide dF4
分子名称: Bcl-2-related protein A1, dF4
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
1ZA6
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BU of 1za6 by Molmil
The structure of an antitumor CH2-domain-deleted humanized antibody
分子名称: IGG Heavy chain, IGG Light chain
著者Larson, S.B, Day, J.S, Glaser, S, Braslawsky, G, McPherson, A.
登録日2005-04-05
公開日2005-05-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of an Antitumor C(H)2-domain-deleted Humanized Antibody.
J.Mol.Biol., 348, 2005
7E6G
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BU of 7e6g by Molmil
Crystal structure of diguanylate cyclase SiaD in complex with its activator SiaC from Pseudomonas aeruginosa
分子名称: DUF1987 domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Zhou, J.S, Zhang, L, Zhang, L.
登録日2021-02-22
公開日2021-09-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for diguanylate cyclase activation by its binding partner in Pseudomonas aeruginosa .
Elife, 10, 2021
2OCG
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BU of 2ocg by Molmil
Crystal structure of human valacyclovir hydrolase
分子名称: GLYCEROL, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Lai, L, Xu, Z, Amidon, G.L.
登録日2006-12-20
公開日2008-02-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2ONM
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BU of 2onm by Molmil
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with NAD+
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Aldehyde dehydrogenase, ...
著者Larson, H.N, Hurley, T.D.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONO
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BU of 2ono by Molmil
Arg475Gln Mutant of Mitochondrial Aldehyde Dehydrogenase, apo form, pseudo-merohedrally twinned
分子名称: Aldehyde dehydrogenase
著者Larson, H.N, Hurley, T.D.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONN
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BU of 2onn by Molmil
Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, Apo form
分子名称: Aldehyde dehydrogenase
著者Larson, H.N, Hurley, T.D.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2ONP
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BU of 2onp by Molmil
Arg475Gln Mutant of Human Mitochondrial Aldehyde Dehydrogenase, complexed with NAD+
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ...
著者Larson, H.N, Hurley, T.D.
登録日2007-01-24
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
J.Biol.Chem., 282, 2007
2OCI
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BU of 2oci by Molmil
Crystal structure of valacyclovir hydrolase complexed with a product analogue
分子名称: L-TYROSINAMIDE, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Lai, L, Xu, Z, Amidon, G.L.
登録日2006-12-20
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCK
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BU of 2ock by Molmil
Crystal structure of valacyclovir hydrolase D123N mutant
分子名称: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
著者Lai, L, Xu, Z, Amidon, G.L.
登録日2006-12-20
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
2OCL
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BU of 2ocl by Molmil
Crystal structure of valacyclovir hydrolase S122A mutant
分子名称: MAGNESIUM ION, MANGANESE (II) ION, Valacyclovir hydrolase
著者Lai, L, Xu, Z, Amidon, G.L.
登録日2006-12-20
公開日2008-02-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
J.Biol.Chem., 283, 2008
7YHW
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BU of 7yhw by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F.
登録日2022-07-14
公開日2023-07-19
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023

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