5C31
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5C35
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5CE4
| High Resolution X-Ray and Neutron diffraction structure of H-FABP | 分子名称: | Fatty acid-binding protein, heart, OLEIC ACID | 著者 | Podjarny, A.D, Howard, E.I, Blakeley, M.P, Guillot, B. | 登録日 | 2015-07-06 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | NEUTRON DIFFRACTION (0.98 Å), X-RAY DIFFRACTION | 主引用文献 | High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution. Iucrj, 3, 2016
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7D3I
| Crystal structure of SARS-CoV-2 main protease in complex with MI-23 | 分子名称: | (3~{S},3~{a}~{S},6~{a}~{R})-2-[3-[3,5-bis(fluoranyl)phenyl]propanoyl]-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-3-carboxamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase | 著者 | Zeng, R, Li, Y.S, Qiao, J.X, Wang, Y.F, Yang, S.Y, Lei, J. | 登録日 | 2020-09-19 | 公開日 | 2020-10-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model. Science, 371, 2021
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5AB3
| S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | 著者 | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | 登録日 | 2015-07-31 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5AC7
| S. enterica HisA with mutations D7N, D10G, dup13-15 | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, GLYCEROL, SODIUM ION, ... | 著者 | Newton, M, Guo, X, Soderholm, A, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | 登録日 | 2015-08-12 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4ZTM
| Irak4-inhibitor co-structure | 分子名称: | 5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3H)-one, Interleukin-1 receptor-associated kinase 4 | 著者 | Fischmann, T.O. | 登録日 | 2015-05-14 | 公開日 | 2015-09-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors. Acs Med.Chem.Lett., 6, 2015
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7CZO
| N-terminal domain of HipA toxin | 分子名称: | CHLORIDE ION, Uncharacterized protein HI_0666 | 著者 | Kang, S.M. | 登録日 | 2020-09-09 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Haemophilus influenzae HipBA toxin-antitoxin system adopts an unusual three-com-ponent regulatory mechanism Iucrj, 9, 2022
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7BDX
| Armadillo domain of HSF2BP in complex with BRCA2 peptide | 分子名称: | Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein, MAGNESIUM ION | 著者 | Le Du, M.H, Zinn-Justin, S, Ghouil, R, Miron, S, Legrand, P. | 登録日 | 2020-12-22 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination. Nat Commun, 12, 2021
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7BO9
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7BO8
| A hexameric de novo coiled-coil assembly: CC-Type2-(VaYd)4-Y3F-W19(BrPhe)-Y24F. | 分子名称: | 1,2-ETHANEDIOL, CC-Type2-(VaYd)4-Y3F-W19(BrPhe)-Y24F, OXAMIC ACID | 著者 | Rhys, G.G, Brady, R.L, Woolfson, D.N. | 登録日 | 2021-01-24 | 公開日 | 2021-05-19 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | How Coiled-Coil Assemblies Accommodate Multiple Aromatic Residues. Biomacromolecules, 22, 2021
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7BOA
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5C34
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5C32
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5DOO
| The structure of PKMT2 from Rickettsia typhi | 分子名称: | CALCIUM ION, protein lysine methyltransferase 2 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-11 | 公開日 | 2016-08-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.133 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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5DNK
| The structure of PKMT1 from Rickettsia prowazekii in complex with AdoHcy | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 1 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-10 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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5DPL
| The structure of PKMT2 from Rickettsia typhi in complex with AdoHcy | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, protein lysine methyltransferase 2 | 著者 | Noinaj, N, Abeykoon, A, He, Y, Yang, D.C, Buchanan, S.K. | 登録日 | 2015-09-12 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural Insights into Substrate Recognition and Catalysis in Outer Membrane Protein B (OmpB) by Protein-lysine Methyltransferases from Rickettsia. J.Biol.Chem., 291, 2016
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5ZND
| 8-mer nanotube derived from 24-mer rHuHF nanocage | 分子名称: | Ferritin heavy chain | 著者 | Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F. | 登録日 | 2018-04-09 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings. J. Am. Chem. Soc., 140, 2018
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1SAK
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1SAE
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1SAF
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6ABH
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6AY9
| Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide | 分子名称: | CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... | 著者 | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2017-09-07 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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1TOM
| ALPHA-THROMBIN COMPLEXED WITH HIRUGEN | 分子名称: | ALPHA-THROMBIN, HIRUGEN, METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE | 著者 | Chen, Z. | 登録日 | 1996-12-06 | 公開日 | 1997-03-12 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor. Bioorg.Med.Chem.Lett., 7, 1997
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6AYA
| Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide | 分子名称: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... | 著者 | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | 登録日 | 2017-09-07 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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