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6RWM
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BU of 6rwm by Molmil
SIVrcm intasome in complex with bictegravir
分子名称: Bictegravir, CHLORIDE ION, DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), ...
著者Cherepanov, P, Nans, A, Cook, N.
登録日2019-06-05
公開日2020-02-05
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
Science, 367, 2020
6SKN
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BU of 6skn by Molmil
Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,8)
分子名称: Gag protein
著者Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P.
登録日2019-08-16
公開日2020-08-26
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A.
Nat.Struct.Mol.Biol., 27, 2020
6DS6
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BU of 6ds6 by Molmil
Crystal structure of p300 ZZ domain in complex with histone H3 peptide
分子名称: CHLORIDE ION, Histone H3 peptide-Histone acetyltransferase p300 Chimeric protein, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2018-06-13
公開日2018-08-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3.
Nat. Struct. Mol. Biol., 25, 2018
2GJJ
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BU of 2gjj by Molmil
Crystal structure of a single chain antibody scA21 against Her2/ErbB2
分子名称: A21 single-chain antibody fragment against erbB2, GLYCEROL
著者Zhu, Z.
登録日2006-03-31
公開日2006-10-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Epitope mapping and structural analysis of an anti-ErbB2 antibody A21: Molecular basis for tumor inhibitory mechanism
Proteins, 70, 2007
8ZVF
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BU of 8zvf by Molmil
AtALMT9 plus high malate in low pH
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, Aluminum-activated malate transporter 9
著者Gong, D.S.
登録日2024-06-11
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Structural insight into the Arabidopsis vacuolar anion channel ALMT9 shows clade specificity.
Cell Rep, 43, 2024
8YPU
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BU of 8ypu by Molmil
Cryo-EM structure of ButCD complex
分子名称: Membrane protein, SusC/RagA family TonB-linked outer membrane protein
著者Xu, J.H, Chen, Z, Gao, X.
登録日2024-03-18
公開日2024-09-25
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues.
Nat Commun, 15, 2024
8YPT
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BU of 8ypt by Molmil
Cryo-EM structure of BfUbb-ButCD complex
分子名称: Membrane protein, TonB-linked outer membrane protein, Ubiquitin-like protein
著者Xu, J.H, Chen, Z, Gao, X.
登録日2024-03-18
公開日2024-09-25
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献A highly conserved SusCD transporter determines the import and species-specific antagonism of Bacteroides ubiquitin homologues.
Nat Commun, 15, 2024
9D3E
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BU of 9d3e by Molmil
Cryo-EM structure of CCR6 bound by SQA1 and OXM2
分子名称: 4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide, CHOLESTEROL, Human CCR6, ...
著者Wasilko, D.J, Wu, H.
登録日2024-08-09
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structural basis for CCR6 modulation by allosteric antagonists.
Nat Commun, 15, 2024
9D3G
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BU of 9d3g by Molmil
Cryo-EM structure of CCR6 bound by SQA1 and OXM1
分子名称: 1-(4-chlorophenyl)-N-{[(2R)-4-(2,3-dihydro-1H-inden-2-yl)-5-oxomorpholin-2-yl]methyl}cyclopropane-1-carboxamide, 4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide, CCR6, ...
著者Wasilko, D.J, Wu, H.
登録日2024-08-10
公開日2024-09-11
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural basis for CCR6 modulation by allosteric antagonists.
Nat Commun, 15, 2024
6J6M
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BU of 6j6m by Molmil
Co-crystal structure of BTK kinase domain with Zanubrutinib
分子名称: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK
著者Zhou, X, Hong, Y.
登録日2019-01-15
公開日2019-10-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
5HYX
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BU of 5hyx by Molmil
Plant peptide hormone receptor RGFR1 in complex with RGF1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ...
著者Song, W, Han, Z, Chai, J.
登録日2016-02-02
公開日2017-01-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth
Cell Res., 26, 2016
7FIV
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BU of 7fiv by Molmil
Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidA and CidBND1-ND2 from wPip(Tunis)
分子名称: CidA_I gamma/2 protein, CidB_I b/2 protein
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-08-01
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.
Nat Commun, 13, 2022
7FIW
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BU of 7fiw by Molmil
Crystal structure of the complex formed by Wolbachia cytoplasmic incompatibility factors CidAwMel(ST) and CidBND1-ND2 from wPip(Pel)
分子名称: ULP_PROTEASE domain-containing protein, bacteria factor 4,CidA I(Zeta/1) protein
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-08-01
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.
Nat Commun, 13, 2022
7FIU
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BU of 7fiu by Molmil
Crystal structure of the DUB domain of Wolbachia cytoplasmic incompatibility factor CidB from wMel
分子名称: ULP_PROTEASE domain-containing protein
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-08-01
公開日2022-04-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.
Nat Commun, 13, 2022
7FIT
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BU of 7fit by Molmil
Crystal structure of Wolbachia cytoplasmic incompatibility factor CidA from wMel
分子名称: bacteria factor 1
著者Xiao, Y.J, Wang, W, Chen, X, Ji, X.Y, Yang, H.T.
登録日2021-08-01
公開日2022-04-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue.
Nat Commun, 13, 2022
5Z9T
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BU of 5z9t by Molmil
a new PL6 alginate lyase complex with trisaccharide
分子名称: GLYCEROL, MALONATE ION, SODIUM ION, ...
著者Liu, W.Z, Lyu, Q.Q, Zhang, K.K, Li, Z.J.
登録日2018-02-05
公開日2019-03-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution.
Biochim Biophys Acta Gen Subj, 1863, 2019
5TOZ
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BU of 5toz by Molmil
JAK3 with covalent inhibitor PF-06651600
分子名称: 1-{(2S,5R)-2-methyl-5-[(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one, SULFATE ION, Tyrosine-protein kinase JAK3
著者Vajdos, F.F.
登録日2016-10-19
公開日2016-11-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.
ACS Chem. Biol., 11, 2016
4OE1
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BU of 4oe1 by Molmil
Crystal structure of the pentatricopeptide repeat protein PPR10 (C256S/C430S/C449S) in complex with an 18-nt PSAJ rna element
分子名称: Chloroplast pentatricopeptide repeat protein 10, PHOSPHATE ION, psaJ RNA
著者Li, Q, Yan, C, Wu, J, Yin, P, Yan, N.
登録日2014-01-11
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10).
J.Biol.Chem., 289, 2014
2JPH
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BU of 2jph by Molmil
NMR solution structure of the Rho GTPase binding domain of human plexin-b1
分子名称: Plexin-B1
著者Tong, Y, Buck, M.
登録日2007-05-11
公開日2008-03-18
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Insights into Oncogenic Mutations of Plexin-B1 Based on the Solution Structure of the Rho GTPase Binding Domain
Structure, 16, 2008
7X8C
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BU of 7x8c by Molmil
Crystal structure of a KTSC family protein from Euryarchaeon Methanolobus vulcani
分子名称: KTSC domain-containing protein, SODIUM ION
著者Zhang, Z.F, Zhu, K.L, Chen, Y.Y, Cao, P, Gong, Y.
登録日2022-03-12
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Biochemical and structural characterization of a KTSC family single-stranded DNA-binding protein from Euryarchaea.
Int.J.Biol.Macromol., 216, 2022
2RDO
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BU of 2rdo by Molmil
50S subunit with EF-G(GDPNP) and RRF bound
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
著者Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
登録日2007-09-24
公開日2008-03-04
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
7DYY
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BU of 7dyy by Molmil
Crystal structure of VIM-2 MBL in complex with 1-((2-aminobenzo[d]thiazol-6-yl)methyl)-1H-imidazole-2-carboxylic acid
分子名称: 1-[(2-azanyl-1,3-benzothiazol-6-yl)methyl]imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, DI(HYDROXYETHYL)ETHER, ...
著者Yan, Y.-H, Li, G.-B.
登録日2021-01-23
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DZ1
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BU of 7dz1 by Molmil
Crystal structure of VIM-2 MBL in complex with 1-benzyl-5-methyl-1H-imidazole-2-carboxylic acid
分子名称: 5-methyl-1-(phenylmethyl)imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION
著者Yan, Y.-H, Li, G.-B.
登録日2021-01-23
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DZ0
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BU of 7dz0 by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-5-methyl-1H-imidazole-2-carboxylic acid
分子名称: 1-but-3-enyl-5-methyl-imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION
著者Yan, Y.-H, Li, G.-B.
登録日2021-01-23
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.227 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022
7DYZ
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BU of 7dyz by Molmil
Crystal structure of VIM-2 MBL in complex with 1-(but-3-en-1-yl)-4-methyl-1H-imidazole-2-carboxylic acid
分子名称: 1-but-3-enyl-4-methyl-imidazole-2-carboxylic acid, Beta-lactamase class B VIM-2, GLYCEROL, ...
著者Yan, Y.-H, Li, G.-B.
登録日2021-01-23
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors.
Eur.J.Med.Chem., 228, 2022

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