8U32
| Crystal structure of PD-1 in complex with a Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | 著者 | Sun, D, Masureel, M. | 登録日 | 2023-09-07 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability. Mabs, 16, 2024
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6AGK
| The structure of CH-II-77-tubulin complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Chen, H, Arnst, K, Wang, Y, Miller, D, Li, W. | 登録日 | 2018-08-13 | 公開日 | 2019-08-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. J.Med.Chem., 63, 2020
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2TDX
| DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL | 分子名称: | DIPHTHERIA TOX REPRESSOR, NICKEL (II) ION | 著者 | White, A, Ding, X, Zheng, H, Schiering, N, Ringe, D, Murphy, J.R. | 登録日 | 1998-06-22 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature, 394, 1998
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2SOB
| SN-OB, OB-FOLD SUB-DOMAIN OF STAPHYLOCOCCAL NUCLEASE, NMR, 10 STRUCTURES | 分子名称: | STAPHYLOCOCCAL NUCLEASE | 著者 | Alexandrescu, A.T, Gittis, A.G, Abeygunawardana, C, Shortle, D. | 登録日 | 1995-09-15 | 公開日 | 1995-12-07 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of a stable "OB-fold" sub-domain isolated from staphylococcal nuclease. J.Mol.Biol., 250, 1995
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32C2
| STRUCTURE OF AN ACTIVITY SUPPRESSING FAB FRAGMENT TO CYTOCHROME P450 AROMATASE | 分子名称: | IGG1 ANTIBODY 32C2 | 著者 | Sawicki, M.W, Ng, P.C, Burkhart, B, Pletnev, V, Higashiyama, T, Osawa, Y, Ghosh, D. | 登録日 | 1999-04-21 | 公開日 | 2000-04-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of an activity suppressing Fab fragment to cytochrome P450 aromatase: insights into the antibody-antigen interactions. Mol.Immunol., 36, 1999
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2DRE
| Crystal structure of Water-soluble chlorophyll protein from lepidium virginicum at 2.00 angstrom resolution | 分子名称: | CHLOROPHYLL A, Water-soluble chlorophyll protein | 著者 | Horigome, D, Satoh, H, Itoh, N, Mitsunaga, K, Oonishi, I, Nakagawa, A, Uchida, A. | 登録日 | 2006-06-08 | 公開日 | 2006-12-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural mechanism and photoprotective function of water-soluble chlorophyll-binding protein. J.Biol.Chem., 282, 2007
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3A57
| Crystal structure of Thermostable Direct Hemolysin | 分子名称: | Thermostable direct hemolysin 2 | 著者 | Hashimoto, H, Yanagihara, I, Nakahira, K, Hamada, D, Ikegami, T, Mayanagi, K, Kaieda, S, Fukui, T, Ohnishi, K, Kajiyama, S, Yamane, T, Ikeguchi, M, Honda, T, Shimizu, T, Sato, M. | 登録日 | 2009-08-03 | 公開日 | 2010-03-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin J.Biol.Chem., 285, 2010
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3AEP
| Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing alpha-amino-alpha, beta-butenoic acid-pyridoxal-5'-phosphate | 分子名称: | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, GLYCEROL, METHANETHIOL, ... | 著者 | Karaki, T, Sato, D, Shimizu, A, Nozaki, T, Harada, S. | 登録日 | 2010-02-10 | 公開日 | 2011-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of Entamoeba histolytica methionine gamma-lyase 1 To be Published
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8THX
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8THY
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4MHA
| Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1817 | 分子名称: | 2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-(4-sulfamoylbenzyl)pyrimidine-5-carboxamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Zhang, W, Mciver, A, Stashko, M.A, Deryckere, D, Branchford, B.R, Hunter, D, Kireev, D.B, Miley, D.B.M, Norris-Drouin, J, Stewart, W.M, Lee, M, Sather, S, Zhou, Y, Dipaola, J.A, Machius, M, Janzen, W.P, Earp, H.S, Graham, D.K, Frye, S, Wang, X. | 登録日 | 2013-08-29 | 公開日 | 2014-05-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. J.Med.Chem., 56, 2013
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4HWY
| Trypanosoma brucei procathepsin B solved from 40 fs free-electron laser pulse data by serial femtosecond X-ray crystallography | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cysteine peptidase C (CPC), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Redecke, L, Nass, K, DePonte, D.P, White, T.A, Rehders, D, Barty, A, Stellato, F, Liang, M, Barends, T.R.M, Boutet, S, Williams, G.W, Messerschmidt, M, Seibert, M.M, Aquila, A, Arnlund, D, Bajt, S, Barth, T, Bogan, M.J, Caleman, C, Chao, T.-C, Doak, R.B, Fleckenstein, H, Frank, M, Fromme, R, Galli, L, Grotjohann, I, Hunter, M.S, Johansson, L.C, Kassemeyer, S, Katona, G, Kirian, R.A, Koopmann, R, Kupitz, C, Lomb, L, Martin, A.V, Mogk, S, Neutze, R, Shoemann, R.L, Steinbrener, J, Timneanu, N, Wang, D, Weierstall, U, Zatsepin, N.A, Spence, J.C.H, Fromme, P, Schlichting, I, Duszenko, M, Betzel, C, Chapman, H. | 登録日 | 2012-11-09 | 公開日 | 2012-12-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Science, 339, 2013
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3A32
| Crystal structure of putative threonyl-tRNA synthetase ThrRS-1 from Aeropyrum pernix | 分子名称: | Probable threonyl-tRNA synthetase 1, SULFATE ION, ZINC ION | 著者 | Shimizu, S, Juan, E.C.M, Miyashita, Y, Sato, Y, Hoque, M.M, Suzuki, K, Yogiashi, M, Tsunoda, M, Dock-Bregeon, A.-C, Moras, D, Sekiguchi, T, Takenaka, A. | 登録日 | 2009-06-07 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain J.Mol.Biol., 394, 2009
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8TI3
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3AEO
| Reaction intermediate structure of Entamoeba histolytica methionine gamma-lyase 1 containing methionine alpha, beta-enamine-pyridoxamine-5'-phosphate | 分子名称: | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-4-(methylsulfanyl)but-2-enoic acid, GLYCEROL, Methionine gamma-lyase, ... | 著者 | Karaki, T, Sato, D, Shimizu, A, Nozaki, T, Harada, S. | 登録日 | 2010-02-10 | 公開日 | 2011-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of Entamoeba histolytica methionine gamma-lyase 1 To be Published
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7VEW
| Crystal structure of bacterial chemotaxis-dependent pectin-binding protein SPH1118 in complex with unsaturated trigalacturonic acid | 分子名称: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Anamizu, K, Takase, R, Hio, M, Watanebe, D, Mikami, B, Hashimoto, W. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Substrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation. Sci Rep, 12, 2022
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2DKA
| Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the apo-form | 分子名称: | Phosphoacetylglucosamine mutase | 著者 | Nishitani, Y, Maruyama, D, Nonaka, T, Kita, A, Fukami, T.A, Mio, T, Yamada-Okabe, H, Yamada-Okabe, T, Miki, K. | 登録日 | 2006-04-07 | 公開日 | 2006-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the {alpha}-D-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes. J.Biol.Chem., 281, 2006
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7VEQ
| Crystal structure of bacterial chemotaxis-dependent pectin-binding protein SPH1118 in an open conformation | 分子名称: | GLYCEROL, SPH1118 | 著者 | Anamizu, K, Takase, R, Hio, M, Watanebe, D, Mikami, B, Hashimoto, W. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Substrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation. Sci Rep, 12, 2022
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2DOK
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7VET
| Crystal structure of bacterial chemotaxis-dependent pectin-binding protein SPH1118 in a closed conformation | 分子名称: | SPH1118 | 著者 | Anamizu, K, Takase, R, Hio, M, Watanebe, D, Mikami, B, Hashimoto, W. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Substrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation. Sci Rep, 12, 2022
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7VEV
| Crystal structure of bacterial chemotaxis-dependent pectin-binding protein SPH1118 in complex with MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, SPH1118 | 著者 | Anamizu, K, Takase, R, Hio, M, Watanebe, D, Mikami, B, Hashimoto, W. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | 主引用文献 | Substrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation. Sci Rep, 12, 2022
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7QU5
| X-ray structure of FAD domain of NqrF of Pseudomonas aeruginosa | 分子名称: | DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Stegmann, D, Steuber, J, Fritz, G. | 登録日 | 2022-01-17 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Fast fragment- and compound-screening pipeline at the Swiss Light Source. Acta Crystallogr D Struct Biol, 78, 2022
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7QTY
| X-ray structure of FAD domain of NqrF of Klebsiella pneumoniae | 分子名称: | 1-(furan-2-ylmethyl)-3-(2-methylphenyl)thiourea, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Stegmann, D, Steuber, J, Fritz, G. | 登録日 | 2022-01-17 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Fast fragment- and compound-screening pipeline at the Swiss Light Source. Acta Crystallogr D Struct Biol, 78, 2022
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7QLA
| Structure of the Rab GEF complex Mon1-Ccz1 | 分子名称: | Ccz1, Vacuolar fusion protein MON1 | 著者 | Klink, B.U, Herrmann, E, Antoni, C, Langemeyer, L, Kiontke, S, Gatsogiannis, C, Ungermann, C, Raunser, S, Kuemmel, D. | 登録日 | 2021-12-20 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | 主引用文献 | Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QU3
| X-ray structure of FAD domain of NqrF of Pseudomonas aeruginosa | 分子名称: | 4-(benzimidazol-1-ylmethyl)benzenecarbonitrile, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Stegmann, D, Steuber, J, Fritz, G. | 登録日 | 2022-01-17 | 公開日 | 2022-02-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Fast fragment- and compound-screening pipeline at the Swiss Light Source. Acta Crystallogr D Struct Biol, 78, 2022
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