8GU5
| Wild type poly(ethylene terephthalate) hydrolase | 分子名称: | Poly(ethylene terephthalate) hydrolase | 著者 | Xiao, Y.J, Wang, Z.F. | 登録日 | 2022-09-09 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin. Nat Commun, 13, 2022
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5EOR
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6JD4
| ATPase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ESX-1 secretion system protein EccCb1, MAGNESIUM ION | 著者 | Wang, S.H, Li, J, Rao, Z.H. | 登録日 | 2019-01-31 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into substrate recognition by the type VII secretion system. Protein Cell, 11, 2020
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6J7M
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3KEA
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5EOQ
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5FHA
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5YSW
| Crystal Structure Analysis of Rif16 in complex with R-L | 分子名称: | (2S,12E,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-21-(acetyloxy)-5,6,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-9-yl hydroxyacetate, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Li, F.W, Qi, F.F, Xiao, Y.L, Zhao, G.P, Li, S.Y. | 登録日 | 2017-11-15 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Deciphering the late steps of rifamycin biosynthesis. Nat Commun, 9, 2018
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4IVC
| JAK1 kinase (JH1 domain) in complex with the inhibitor (TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXYL)ACETONITRILE | 分子名称: | (trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexyl)acetonitrile, Tyrosine-protein kinase JAK1 | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2013-01-22 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2. J.Med.Chem., 56, 2013
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5YSM
| Crystal Structure Analysis of Rif16 | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Li, F.W, Qi, F.F, Xiao, Y.L, Zhao, G.P, Li, S.Y. | 登録日 | 2017-11-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Deciphering the late steps of rifamycin biosynthesis. Nat Commun, 9, 2018
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4IVD
| JAK1 kinase (JH1 domain) in complex with compound 34 | 分子名称: | 3-(trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexyl)propanenitrile, Tyrosine-protein kinase JAK1 | 著者 | Eigenbrot, C, Steffek, M. | 登録日 | 2013-01-22 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2. J.Med.Chem., 56, 2013
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4JI9
| JAK2 kinase (JH1 domain) in complex with TG101209 | 分子名称: | N-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide, Tyrosine-protein kinase JAK2 | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2013-03-05 | 公開日 | 2013-08-07 | 最終更新日 | 2013-08-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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4IVB
| JAK1 kinase (JH1 domain) in complex with the inhibitor TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXANECARBONITRILE | 分子名称: | Tyrosine-protein kinase JAK1, trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexanecarbonitrile | 著者 | Eigenbrot, C, Steffek, M. | 登録日 | 2013-01-22 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2. J.Med.Chem., 56, 2013
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4JAJ
| Crystal Structure of Aurora Kinase A in complex with BENZO[C][1,8]NAPHTHYRIDIN-6(5H)-ONE | 分子名称: | Aurora kinase A, benzo[c][1,8]naphthyridin-6(5H)-one | 著者 | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | 登録日 | 2013-02-18 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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2ZGQ
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2ZGP
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2ZGL
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7KX9
| Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA-target complex | 分子名称: | MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*UP*UP*GP*AP*GP*UP*UP*GP*GP*AP*CP*AP*AP*AP*UP*GP*GP*CP*AP*(OMG))-3'), ... | 著者 | Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J. | 登録日 | 2020-12-03 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis for piRNA targeting. Nature, 597, 2021
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7KX7
| Cryo-EM structure of Ephydatia fluviatilis PiwiA-piRNA complex | 分子名称: | MAGNESIUM ION, Piwi-A, RNA (5'-R(P*UP*CP*UP*CP*AP*GP*(OMC))-3') | 著者 | Anzelon, T.A, Chowdhury, S, Lander, G.C, MacRae, I.J. | 登録日 | 2020-12-03 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis for piRNA targeting. Nature, 597, 2021
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2ZGT
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1X8C
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4JAI
| Crystal Structure of Aurora Kinase A in complex with N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | 分子名称: | Aurora kinase A, N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | 著者 | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | 登録日 | 2013-02-18 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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2ZGM
| Crystal structure of recombinant Agrocybe aegerita lectin,rAAL, complex with lactose | 分子名称: | Anti-tumor lectin, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Li, D.F, Yang, N, Wang, D.C. | 登録日 | 2008-01-23 | 公開日 | 2009-01-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009
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2ZGN
| crystal structure of recombinant Agrocybe aegerita lectin, rAAL, complex with galactose | 分子名称: | Anti-tumor lectin, beta-D-galactopyranose | 著者 | Yang, N, Li, D.F, Wang, D.C. | 登録日 | 2008-01-23 | 公開日 | 2009-01-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009
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2ZGS
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