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8F6V
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BU of 8f6v by Molmil
Crystal Structure of Nanobody VHH108 Bound to Its Antigen PA14 Cif
分子名称: CFTR inhibitory factor, Nanobody VHH108
著者Simard, A.R, Madden, D.R.
登録日2022-11-17
公開日2024-03-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Nanobody VHH113 Bound to Its Antigen PA14 Cif
To Be Published
4J0Q
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BU of 4j0q by Molmil
Crystal structure of Pseudomonas putida elongation factor Tu (EF-Tu)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Elongation factor Tu-A, ...
著者Scotti, J.S, McDonough, M.A, Schofield, C.J.
登録日2013-01-31
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
4J25
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BU of 4j25 by Molmil
Crystal structure of a Pseudomonas putida prolyl-4-hydroxylase (P4H)
分子名称: MANGANESE (II) ION, N-OXALYLGLYCINE, Putative uncharacterized protein
著者Scotti, J.S, McDonough, M.A, Schofield, C.J.
登録日2013-02-04
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation
Proc.Natl.Acad.Sci.USA, 111, 2014
2Z7L
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BU of 2z7l by Molmil
Unphosphorylated Mitogen Activated Protein Kinase ERK2 in Complex with (4-{[5-Carbamoyl-4-(3-Methylanilino)Pyrimidin 2-Yl]Amino}Phenyl)Acetic Acid
分子名称: BETA-MERCAPTOETHANOL, Mitogen-activated protein kinase 1, SULFATE ION, ...
著者Katayama, N, Kurihara, H.
登録日2007-08-27
公開日2008-08-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors
Proteins, 73, 2008
3VNU
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BU of 3vnu by Molmil
Complex structure of viral RNA polymerase I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ...
著者Takeshita, D, Tomita, K.
登録日2012-01-18
公開日2012-08-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Mechanism for template-independent terminal adenylation activity of Q beta replicase
Structure, 20, 2012
3VNV
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BU of 3vnv by Molmil
Complex structure of viral RNA polymerase II
分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, Elongation factor Ts, ...
著者Takeshita, D, Tomita, K.
登録日2012-01-18
公開日2012-08-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Mechanism for template-independent terminal adenylation activity of Q beta replicase
Structure, 20, 2012
2Z8C
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BU of 2z8c by Molmil
Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
分子名称: 6-mer peptide from Insulin receptor substrate 1, Insulin receptor, [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID
著者Katayama, N, Kurihara, H.
登録日2007-09-05
公開日2008-08-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors.
Proteins, 73, 2008
1QBS
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BU of 1qbs by Molmil
HIV-1 PROTEASE INHIBITORS WIIH LOW NANOMOLAR POTENCY
分子名称: HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHENYLMETHYL)]-2H-1,3-DIAZEPINONE
著者Ala, P, Chang, C.-H.
登録日1997-04-25
公開日1997-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas.
J.Med.Chem., 39, 1996
2ZTB
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BU of 2ztb by Molmil
Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Crystal protein, ...
著者Akiba, T.
登録日2008-09-29
公開日2009-01-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of the parasporin-2 Bacillus thuringiensis toxin that recognizes cancer cells
J.Mol.Biol., 386, 2009
5IBW
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BU of 5ibw by Molmil
Complex of MlcC bound to the tandem IQ motif of MyoC
分子名称: Calcium-binding EF-hand domain-containing protein, Myosin IC heavy chain, SODIUM ION
著者Langelaan, D.N, Smith, S.P.
登録日2016-02-22
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition.
J.Biol.Chem., 291, 2016
3VKN
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BU of 3vkn by Molmil
Galectin-8 N-terminal domain in free form
分子名称: CHLORIDE ION, Galectin-8
著者Kamitori, S, Yoshida, H.
登録日2011-11-18
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains
Febs J., 279, 2012
3VUO
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BU of 3vuo by Molmil
Crystal structure of nontoxic nonhemagglutinin subcomponent (NTNHA) from clostridium botulinum serotype D strain 4947
分子名称: NTNHA
著者Sagane, Y, Miyashita, S.-I, Miyata, K, Matsumoto, T, Inui, K, Hayashi, S, Suzuki, T, Hasegawa, K, Yajima, S, Yamano, A, Niwa, K, Watanabe, T.
登録日2012-07-03
公開日2012-09-19
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin
Biochem.Biophys.Res.Commun., 425, 2012
3VKL
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BU of 3vkl by Molmil
Protease-resistant mutant form of human Galectin-8 in complex with two lactose molecules
分子名称: 1,2-ETHANEDIOL, Galectin-8, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Kamitori, S, Yoshida, H.
登録日2011-11-18
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains
Febs J., 279, 2012
3VKO
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BU of 3vko by Molmil
Galectin-8 N-terminal domain in complex with sialyllactosamine
分子名称: CHLORIDE ION, Galectin-8, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Kamitori, S, Yoshida, H.
登録日2011-11-18
公開日2012-09-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains
Febs J., 279, 2012
3WJV
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BU of 3wjv by Molmil
Crystal structure of the L68E variant of mLolB
分子名称: Outer-membrane lipoprotein LolB, SULFATE ION
著者Takeda, K, Tokuda, H, Miki, K.
登録日2013-10-16
公開日2014-03-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Roles of the Protruding Loop of Factor B Essential for the Localization of Lipoproteins (LolB) in the Anchoring of Bacterial Triacylated Proteins to the Outer Membran
J.Biol.Chem., 289, 2014
4GJJ
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BU of 4gjj by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with D-allopyranose
分子名称: D-ALLOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
著者Yoshida, H, Kamitori, S.
登録日2012-08-09
公開日2012-12-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
4GJI
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BU of 4gji by Molmil
Crystal structure of Pseudomonas stutzeri L-rhamnose isomerase mutant H101N in complex with L-rhamnopyranose
分子名称: L-RHAMNOSE, L-rhamnose isomerase, MANGANESE (II) ION, ...
著者Yoshida, H, Kamitori, S.
登録日2012-08-09
公開日2012-12-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of l-rhamnose isomerase in complex with l-rhamnopyranose demonstrates the sugar-ring opening mechanism and the role of a substrate sub-binding site.
FEBS Open Bio, 3, 2013
4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
分子名称: CH58 Fab heavy chain, CH58 Fab light chain
著者McLellan, J.S, Haynes, B.F, Kwong, P.D.
登録日2012-10-25
公開日2013-02-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
9C66
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BU of 9c66 by Molmil
Structure of the Mena EVH1 domain bound to the polyproline segment of PTP1B
分子名称: 1,2-ETHANEDIOL, Protein enabled homolog, SULFATE ION, ...
著者LaComb, L, Fedorov, E, Bonanno, J.B, Almo, S.C, Ghosh, A.
登録日2024-06-07
公開日2024-08-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Insights into the Interaction Landscape of the EVH1 Domain of Mena.
Biochemistry, 63, 2024
8GJR
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BU of 8gjr by Molmil
Crystal Structure of Nanobody VHH114 Bound to Its Antigen PA14 Cif
分子名称: CFTR inhibitory factor, CITRATE ANION, Nanobody VHH114
著者Simard, A.R, Madden, D.R.
登録日2023-03-16
公開日2024-06-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Nanobody VHH114 Bound to Its Antigen PA14 Cif
To Be Published
1HVH
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BU of 1hvh by Molmil
NONPEPTIDE CYCLIC CYANOGUANIDINES AS HIV PROTEASE INHIBITORS
分子名称: HIV-1 PROTEASE, {[4-R(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-1,3-BIS(4-HYDROXYMETHYL)METHYL]-4,7-BIS(PHENYLMETHYL) -2H-1,3-DIAZEPIN-2-YLIDENE]CYANAMIDE}
著者Chang, C.-H.
登録日1997-12-13
公開日1998-12-30
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies.
J.Med.Chem., 41, 1998
1HVR
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BU of 1hvr by Molmil
RATIONAL DESIGN OF POTENT, BIOAVAILABLE, NONPEPTIDE CYCLIC UREAS AS HIV PROTEASE INHIBITORS
分子名称: HIV-1 PROTEASE, [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-HEXAHYDRO-5,6-DIHYDROXY-1,3-BIS[2-NAPHTHYL-METHYL]-4,7-BIS(PHENYLMETHYL)-2H-1,3-DIAZEPIN-2-ONE
著者Chang, C.-H.
登録日1994-02-14
公開日1995-01-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors.
Science, 263, 1994
2ZOG
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BU of 2zog by Molmil
Crystal structure of mouse carnosinase CN2 complexed with ZN and bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Cytosolic non-specific dipeptidase, ZINC ION
著者Unno, H, Yamashita, T, Okumura, N, Kusunoki, M.
登録日2008-05-14
公開日2008-06-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.
J.Biol.Chem., 283, 2008
2ZOF
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BU of 2zof by Molmil
Crystal structure of mouse carnosinase CN2 complexed with MN and bestatin
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Cytosolic non-specific dipeptidase, MANGANESE (II) ION
著者Unno, H, Yamashita, T, Okumura, N, Kusunoki, M.
登録日2008-05-14
公開日2008-06-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.
J.Biol.Chem., 283, 2008
7COV
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BU of 7cov by Molmil
Potato D-enzyme, native (substrate free)
分子名称: 4-alpha-glucanotransferase, chloroplastic/amyloplastic, CALCIUM ION, ...
著者Unno, H, Imamura, K.
登録日2020-08-05
公開日2020-08-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato.
Protein Sci., 29, 2020

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