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4RTM
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BU of 4rtm by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTP
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BU of 4rtp by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with AdoMet and with DNA Containing Proximal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTK
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BU of 4rtk by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with SAH and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
4RTL
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BU of 4rtl by Molmil
Complex of Escherichia coli DNA Adenine Methyltransferase (DAM) with Sinefungin and with DNA Containing Distal Pap Regulon Sequence
分子名称: DNA (5'-D(*AP*CP*GP*AP*TP*CP*TP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*AP*GP*AP*TP*CP*G)-3'), DNA adenine methylase, ...
著者Horton, J.R, Cheng, X.
登録日2014-11-15
公開日2015-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Structures of Escherichia coli DNA adenine methyltransferase (Dam) in complex with a non-GATC sequence: potential implications for methylation-independent transcriptional repression.
Nucleic Acids Res., 43, 2015
1MOZ
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BU of 1moz by Molmil
ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae
分子名称: ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE
著者Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A.
登録日2002-09-10
公開日2002-10-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structures of Yeast ARF2 and ARL1: DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
1F3L
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BU of 1f3l by Molmil
CRYSTAL STRUCTURE OF THE CONSERVED CORE OF PROTEIN ARGININE METHYLTRANSFERASE PRMT3
分子名称: PROTEIN ARGININE METHYLTRANSFERASE PRMT3, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhang, X, Zhou, L, Cheng, X.
登録日2000-06-05
公開日2001-03-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of the conserved core of protein arginine methyltransferase PRMT3.
EMBO J., 19, 2000
1KHC
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BU of 1khc by Molmil
Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b
分子名称: DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION
著者Qiu, C, Sawada, K, Zhang, X, Cheng, X.
登録日2001-11-29
公開日2002-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol., 9, 2002
1ML9
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BU of 1ml9 by Molmil
Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase
分子名称: Histone H3 methyltransferase DIM-5, UNKNOWN, ZINC ION
著者Zhang, X, Tamaru, H, Khan, S.I, Horton, J.R, Keefe, L.J, Selker, E.U, Cheng, X.
登録日2002-08-30
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
1NGN
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BU of 1ngn by Molmil
Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
分子名称: methyl-CpG binding protein MBD4
著者Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X.
登録日2002-12-17
公開日2003-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
J.Biol.Chem., 278, 2003
1MR3
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BU of 1mr3 by Molmil
Saccharomyces cerevisiae ADP-ribosylation Factor 2 (ScArf2) complexed with GDP-3'P at 1.6A resolution
分子名称: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, ADP-ribosylation factor 2, ...
著者Amor, J.-C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A.
登録日2002-09-17
公開日2002-11-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of yeast ARF2 and ARL1: distinct roles for the N terminus in the structure and function of ARF family GTPases.
J.Biol.Chem., 276, 2001
1G55
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BU of 1g55 by Molmil
Structure of human DNMT2, an enigmatic DNA methyltransferase homologue
分子名称: BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ...
著者Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X.
登録日2000-10-30
公開日2001-01-17
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
Nucleic Acids Res., 29, 2001
1JQD
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BU of 1jqd by Molmil
Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine
分子名称: HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X.
登録日2001-08-06
公開日2002-08-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1U2Z
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BU of 1u2z by Molmil
Crystal structure of histone K79 methyltransferase Dot1p from yeast
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE
著者Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X.
登録日2004-07-20
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
6WE9
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BU of 6we9 by Molmil
YTH domain of human YTHDC1 with 11mer ssDNA Containing N6mA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*GP*(6MA)P*CP*TP*CP*TP*G)-3'), GLYCEROL, ...
著者Horton, J.R, Cheng, X.
登録日2020-04-01
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA.
Nucleic Acids Res., 48, 2020
6WEA
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BU of 6wea by Molmil
YTH domain of human YTHDC1 with a 10mer Oligo Containing N6mA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*GP*(6MA)P*CP*TP*TP*C)-3'), SODIUM ION, ...
著者Horton, J.R, Cheng, X.
登録日2020-04-01
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA.
Nucleic Acids Res., 48, 2020
6WK2
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BU of 6wk2 by Molmil
SETD3 mutant (N255V) in Complex with an Actin Peptide with His73 Replaced with Methionine
分子名称: 1,2-ETHANEDIOL, Actin, cytoplasmic 2, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2020-04-15
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
J.Biol.Chem., 295, 2020
6WMI
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BU of 6wmi by Molmil
ZNF410 zinc fingers 1-5 with 17 mer blunt DNA Oligonucleotide
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*CP*AP*TP*AP*AP*TP*AP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*TP*AP*TP*GP*GP*GP*AP*TP*GP*TP*G)-3'), ...
著者Ren, R, Horton, J.R, Cheng, X.
登録日2020-04-21
公開日2020-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Mol.Cell, 81, 2021
6WK1
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BU of 6wk1 by Molmil
SETD3 in Complex with an Actin Peptide with His73 Replaced with Methionine
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2020-04-15
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
J.Biol.Chem., 295, 2020
2AOT
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BU of 2aot by Molmil
Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine
分子名称: Histamine N-methyltransferase, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, S-ADENOSYL-L-HOMOCYSTEINE
著者Horton, J.R, Sawada, K, Nishibori, M, Cheng, X.
登録日2005-08-14
公開日2005-09-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
2AOW
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BU of 2aow by Molmil
Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine
分子名称: Histamine N-methyltransferase, TACRINE
著者Horton, J.R, Sawada, K, Nishibori, M, Cheng, X.
登録日2005-08-14
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
7RNV
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BU of 7rnv by Molmil
SH2 domain of guanine nucleotide exchange factor Vav2 in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNS
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BU of 7rns by Molmil
nSH2 domain of p85-alpha subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
7RNU
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BU of 7rnu by Molmil
nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2021-07-29
公開日2021-08-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin
To Be Published
1YFL
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BU of 1yfl by Molmil
T4Dam in Complex with Sinefungin and 16-mer Oligonucleotide Showing Semi-specific and Specific Contact and Flipped Base
分子名称: 5'-D(P*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*GP*A)-3', DNA adenine methylase, SINEFUNGIN
著者Horton, J.R, Liebert, K, Hattman, S, Jeltsch, A, Cheng, X.
登録日2005-01-03
公開日2005-05-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
5IVB
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A High Resolution Structure of a Linked KDM5A Jmj Domain with Alpha-Ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, GLYCEROL, Lysine-specific demethylase 5A,Lysine-specific demethylase 5A, ...
著者Horton, J.R, Cheng, X.
登録日2016-03-20
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.389 Å)
主引用文献Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.
Cell Chem Biol, 23, 2016

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