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4GPL
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BU of 4gpl by Molmil
Structure of Cbl(TKB) bound to a phosphorylated pentapeptide
分子名称: ACE-PTR-THR-PRO-GLU-PRO, PEPTIDE INHIBITOR, E3 ubiquitin-protein ligase CBL
著者Borgstahl, G, Natarajan, A.
登録日2012-08-21
公開日2013-09-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides.
Sci Rep, 3, 2013
7XVG
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BU of 7xvg by Molmil
Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35
分子名称: AvrSr35, Sr35
著者Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X.
登録日2022-05-23
公開日2022-09-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism.
Sci Adv, 8, 2022
7Y3E
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BU of 7y3e by Molmil
Cryo-EM structure of Arabidopsis thaliana SOS1 in an occluded state
分子名称: HEXADECANE, Sodium/hydrogen exchanger 7
著者Wang, Y, Zhao, Y, Gao, Y.
登録日2022-06-10
公開日2023-08-09
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Architecture and autoinhibitory mechanism of the plasma membrane Na + /H + antiporter SOS1 in Arabidopsis.
Nat Commun, 14, 2023
7DE1
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BU of 7de1 by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal RNA binding domain
分子名称: DI(HYDROXYETHYL)ETHER, Nucleoprotein
著者Chen, S, Kang, S.
登録日2020-11-01
公開日2021-01-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences.
Front Chem, 8, 2020
5J8V
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BU of 5j8v by Molmil
Structure of rabbit ryanodine receptor RyR1 open state activated by calcium ion
分子名称: Ryanodine receptor 1
著者Wang, X, Wei, R, Yin, C, Sun, F.
登録日2016-04-08
公開日2016-09-14
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1
Cell Res., 26, 2016
7V6L
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BU of 7v6l by Molmil
LcCOMT in complex with SAH
分子名称: LcCOMT, S-ADENOSYL-L-HOMOCYSTEINE
著者Yu, Y, CHen, Q.
登録日2021-08-20
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Structure basis of the caffeic acid O-methyltransferase from Ligusiticum chuanxiong to understand its selective mechanism.
Int.J.Biol.Macromol., 194, 2022
7V6J
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BU of 7v6j by Molmil
LcCOMT in complex with SAM
分子名称: LcCOMT, S-ADENOSYLMETHIONINE, SODIUM ION
著者Yu, Y, CHen, Q.
登録日2021-08-20
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structure basis of the caffeic acid O-methyltransferase from Ligusiticum chuanxiong to understand its selective mechanism.
Int.J.Biol.Macromol., 194, 2022
6J8R
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BU of 6j8r by Molmil
Metallo-Beta-Lactamase VIM-2 in complex with Dual MBL/SBL Inhibitor MS01
分子名称: Beta-lactamase class B VIM-2, FORMIC ACID, GLYCEROL, ...
著者Li, G.-B, Liu, S.
登録日2019-01-21
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.575 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
6J8Q
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BU of 6j8q by Molmil
Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor WL-001
分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Li, G.-B, Liu, S.
登録日2019-01-21
公開日2019-07-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
6JN4
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BU of 6jn4 by Molmil
Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor WL-001
分子名称: ACETATE ION, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Li, G.-B, Liu, S.
登録日2019-03-13
公開日2019-07-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
6JN5
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BU of 6jn5 by Molmil
Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor MS23
分子名称: Serine Beta-Lactamase KPC-2, [(S)-(4-fluorophenyl)-[[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]methyl]boronic acid
著者Li, G.-B, Liu, S.
登録日2019-03-13
公開日2019-07-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
6JN3
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BU of 6jn3 by Molmil
Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor MS05
分子名称: ACETIC ACID, DI(HYDROXYETHYL)ETHER, Serine Beta-Lactamase KPC-2, ...
著者Li, G.-B, Liu, S.
登録日2019-03-13
公開日2019-07-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.216 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
6JN6
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BU of 6jn6 by Molmil
Metallo-Beta-Lactamase VIM-2 in complex with Dual MBL/SBL Inhibitor MS19
分子名称: Beta-lactamase class B VIM-2, FORMIC ACID, ZINC ION, ...
著者Li, G.-B, Liu, S.
登録日2019-03-13
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-beta-lactamases.
J.Med.Chem., 62, 2019
8WWF
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BU of 8wwf by Molmil
Crystal structure of (R)-DHPS dehydrogenase HpsO from Ruegeria pomeroyi DSS-3
分子名称: (R)-DHPS dehydrogenase HpsO
著者Liu, L, Tang, K.
登録日2023-10-25
公開日2024-09-04
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Enantioselective transformation of phytoplankton-derived dihydroxypropanesulfonate by marine bacteria.
Isme J, 18, 2024
8WWE
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BU of 8wwe by Molmil
Crystal structure of (R)-DHPS dehydrogenase HpsN from Ruegeria pomeroyi DSS-3
分子名称: (R)-DHPS dehydrogenase, SULFATE ION
著者Liu, L, Tang, K.
登録日2023-10-25
公開日2024-09-04
最終更新日2024-09-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Enantioselective transformation of phytoplankton-derived dihydroxypropanesulfonate by marine bacteria.
Isme J, 18, 2024
8UG4
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BU of 8ug4 by Molmil
Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 8.0
分子名称: Otopetrin-2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8WWD
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BU of 8wwd by Molmil
Crystal structure of (S)-DHPS dehydrogenase HpsP from Dinoroseobacter shibae DFL 12
分子名称: ZINC ION, Zinc-containing alcohol dehydrogenase
著者Liu, L, Tang, K.
登録日2023-10-25
公開日2024-09-04
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Enantioselective transformation of phytoplankton-derived dihydroxypropanesulfonate by marine bacteria.
Isme J, 18, 2024
8UG7
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BU of 8ug7 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 8.0
分子名称: Proton channel OTOP2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG5
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BU of 8ug5 by Molmil
Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 5.0
分子名称: Otopetrin-2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UGA
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BU of 8uga by Molmil
Mus musculus Otopetrin 2 (mOTOP2) M374W in pH 8.0
分子名称: Proton channel OTOP2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG6
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BU of 8ug6 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 5.0
分子名称: Proton channel OTOP2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG8
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BU of 8ug8 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 7.0, intermediate state
分子名称: Proton channel OTOP2
著者Gan, N, Jiang, Y.
登録日2023-10-05
公開日2024-08-21
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8WX8
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BU of 8wx8 by Molmil
De novo design protein -T09
分子名称: De novo design protein -T09
著者Wang, C, Wang, S, Liu, Y.
登録日2023-10-27
公開日2024-10-09
最終更新日2025-05-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
8WWC
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BU of 8wwc by Molmil
De novo design binder of HRAS -120-4
分子名称: De novo design protein 120-4, GTPase HRas, MAGNESIUM ION, ...
著者Wang, L, Wang, S, Liu, Y.
登録日2023-10-25
公開日2024-10-09
最終更新日2025-05-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献De novo protein design with a denoising diffusion network independent of pretrained structure prediction models.
Nat.Methods, 21, 2024
8XTV
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BU of 8xtv by Molmil
Crystal structure of AaHPPD-Y14150 complex
分子名称: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, [3-ethyl-1-methyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone
著者Dong, J, Lin, H.-Y, Yang, G.-F.
登録日2024-01-11
公開日2025-01-15
最終更新日2025-07-02
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Repurposing 4-Hydroxyphenylpyruvate dioxygenase inhibitors as novel agents for mosquito control: A structure-based design approach.
Int.J.Biol.Macromol., 315, 2025

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