6WNL
| human Artemis/SNM1C catalytic domain, crystal form 2 | 分子名称: | Protein artemis, ZINC ION | 著者 | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | 登録日 | 2020-04-22 | 公開日 | 2020-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
|
|
3L2I
| 1.85 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2. | 分子名称: | 3-dehydroquinate dehydratase, MAGNESIUM ION | 著者 | Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-12-15 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding. Biochemistry, 50, 2011
|
|
6WUI
| Crystal Structure of mutant S. pombe Rai1 (E150S/E199Q/E239Q) in complex with 3'-FADP | 分子名称: | Decapping nuclease din1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | 著者 | Doamekpor, S.K, Tong, L. | 登録日 | 2020-05-04 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. Nucleic Acids Res., 48, 2020
|
|
6WM3
| Human V-ATPase in state 2 with SidK and ADP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ... | 著者 | Wang, L, Wu, H, Fu, T.M. | 登録日 | 2020-04-20 | 公開日 | 2020-11-11 | 最終更新日 | 2020-11-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Mol.Cell, 80, 2020
|
|
7CFM
| Cryo-EM structure of the P395-bound GPBAR-Gs complex | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
|
|
4H2E
| Crystal structure of an MMP twin inhibitor complexing two MMP-9 catalytic domains | 分子名称: | ACETATE ION, BICINE, CALCIUM ION, ... | 著者 | Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Catalani, M.P, Dive, V, Rossello, A. | 登録日 | 2012-09-12 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182, 2013
|
|
6X2D
| Crystal Structure of DNase I Domain of Ribonuclease E from Vibrio cholerae | 分子名称: | IODIDE ION, Ribonuclease E | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Wiersum, G, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-05-20 | 公開日 | 2020-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of DNase I Domain of Ribonuclease E from Vibrio cholerae. To Be Published
|
|
6WEN
| Crystal Structure of ADP ribose phosphatase of NSP3 from SARS-CoV-2 in the apo form | 分子名称: | CHLORIDE ION, Non-structural protein 3 | 著者 | Michalska, K, Stols, L, Jedrzejczak, R, Endres, M, Babnigg, G, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-04-02 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
|
|
6WGF
| Atomic model of mutant Mcm2-7 hexamer with Mcm6 WHD truncation | 分子名称: | DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6WUF
| Crystal structure of mouse DXO in complex with 3'-FADP | 分子名称: | 1,2-ETHANEDIOL, Decapping and exoribonuclease protein, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | 著者 | Doamekpor, S.K, Tong, L. | 登録日 | 2020-05-04 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. Nucleic Acids Res., 48, 2020
|
|
6WYF
| |
6X0V
| Structure of MZT2/GCP-NHD and CDK5Rap2 at position 13 of the gamma-TuRC | 分子名称: | Centrosome protein Cep215, Gamma-tubulin complex component 2, Mitotic-spindle organizing protein 2A | 著者 | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | 登録日 | 2020-05-17 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
|
|
5DHS
| Crystal structure of NAD kinase 1 from Listeria monocytogenes in complex with a novel inhibitor | 分子名称: | 5'-azido-5'-deoxy-8-[(2-{[2-(3-ethynylphenyl)ethyl]amino}-2-oxoethyl)sulfanyl]adenosine, CITRIC ACID, GLYCEROL, ... | 著者 | Gelin, M, Paoletti, J, Assairi, L, Huteau, V, Pochet, S, Labesse, G. | 登録日 | 2015-08-31 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | 8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode. Eur.J.Med.Chem., 124, 2016
|
|
6WM7
| Periplasmic EDTA-binding protein EppA, orthorhombic | 分子名称: | 1,2-ETHANEDIOL, Extracellular solute-binding protein, family 5, ... | 著者 | Lewis, K.M, Greene, C.L, Sattler, S.A, Xun, L, Kang, C. | 登録日 | 2020-04-20 | 公開日 | 2020-11-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | The Structural Basis of the Binding of Various Aminopolycarboxylates by the Periplasmic EDTA-Binding Protein EppA from Chelativorans sp. BNC1. Int J Mol Sci, 21, 2020
|
|
6WPG
| Structural Basis of Salicylic Acid Perception by Arabidopsis NPR Proteins | 分子名称: | 2-HYDROXYBENZOIC ACID, Regulatory protein NPR4 | 著者 | Wang, W, Withers, J, Li, H, Zwack, P.J, Rusnac, D.V, Shi, H, Liu, L, Yan, S, Hinds, T.R, Guttman, M, Dong, X, Zheng, N. | 登録日 | 2020-04-27 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.283 Å) | 主引用文献 | Structural basis of salicylic acid perception by Arabidopsis NPR proteins. Nature, 586, 2020
|
|
3MYG
| Aurora A Kinase complexed with SCH 1473759 | 分子名称: | 2-{ethyl[(5-{[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]amino}isothiazol-3-yl)methyl]amino}-2-methylpropan-1-ol, Serine/threonine-protein kinase 6, TETRAETHYLENE GLYCOL | 著者 | Hruza, A, Prosis, W, Ramanathan, L. | 登録日 | 2010-05-10 | 公開日 | 2010-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core. ACS Med Chem Lett, 1, 2010
|
|
6WYH
| |
6X0U
| Structure of MZT1/GCP3-NHD and MZT1/GCP6-NHD in the gamma-TuRC lumenal bridge | 分子名称: | Gamma-tubulin complex component 3, Gamma-tubulin complex component 6, Mitotic-spindle organizing protein 1 | 著者 | Wieczorek, M, Huang, T.-L, Urnavicius, L, Hsia, K.-C, Kapoor, T.M. | 登録日 | 2020-05-17 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | MZT Proteins Form Multi-Faceted Structural Modules in the gamma-Tubulin Ring Complex. Cell Rep, 31, 2020
|
|
4JIO
| Bro1 V domain and ubiquitin | 分子名称: | BRO1, Ubiquitin | 著者 | Pashkova, N, Gakhar, L, Piper, R.C. | 登録日 | 2013-03-06 | 公開日 | 2013-06-19 | 最終更新日 | 2013-07-10 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes. Dev.Cell, 25, 2013
|
|
6WC2
| |
6WK7
| Crystal Structure Analysis of a poly(thymine) DNA duplex | 分子名称: | 1,3,5-triazine-2,4,6-triamine, DNA (5'-D(*TP*TP*TP*TP*TP*T)-3') | 著者 | Li, Q, Zhao, J, Liu, L, Mandal, S, Rizzuto, F.J, He, H, Wei, S, Jonchhe, S, Sleiman, H.F, Mao, H, Mao, C. | 登録日 | 2020-04-15 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.423 Å) | 主引用文献 | A poly(thymine)-melamine duplex for the assembly of DNA nanomaterials. Nat Mater, 19, 2020
|
|
6WKQ
| 1.98 Angstrom Resolution Crystal Structure of NSP16-NSP10 Heterodimer from SARS-CoV-2 in Complex with Sinefungin | 分子名称: | 2'-O-methyltransferase, FORMIC ACID, Non-structural protein 10, ... | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-04-16 | 公開日 | 2020-04-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design. Sci.Signal., 13, 2020
|
|
6WDN
| Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+ | 分子名称: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | 著者 | Feng, L, Zhang, J, Fan, M. | 登録日 | 2020-04-01 | 公開日 | 2020-05-27 | 最終更新日 | 2020-06-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
|
|
6WNT
| 50S ribosomal subunit without free 5S rRNA and perturbed PTC | 分子名称: | 23s-5s joint ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L10, ... | 著者 | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | 登録日 | 2020-04-23 | 公開日 | 2020-06-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nat Commun, 11, 2020
|
|
6WYG
| |