3M01
 
 | | The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate | | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, ACETATE ION, Aristolochene synthase, ... | | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | | 登録日 | 2010-03-02 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
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2MOQ
 | | Solution Structure and Molecular determinants of Hemoglobin Binding of the first NEAT Domain of IsdB in Staphylococcus aureus | | 分子名称: | Iron-regulated surface determinant protein B | | 著者 | Fonner, B.A, Tripet, B.P, Eilers, B.J, Stanisich, J, Sullivan-Springhetti, R.K, Moore, R, Lui, M, Lei, B, Copie, V. | | 登録日 | 2014-04-29 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure and Molecular Determinants of Hemoglobin Binding of the First NEAT Domain of IsdB in Staphylococcus aureus.
Biochemistry, 53, 2014
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7TFD
 | | P. polymyxa GS(12) - apo | | 分子名称: | Glutamine synthetase, MAGNESIUM ION | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TF9
 | | L. monocytogenes GS(14)-Q-GlnR peptide | | 分子名称: | C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TFE
 | | L. monocytogenes GS(12) - apo | | 分子名称: | Glutamine synthetase, MAGNESIUM ION | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TFB
 | | P. polymyxa GS(14)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.28 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TFA
 | | P. polymyxa GS(12)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.07 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TF7
 | | S. aureus GS(12) - apo | | 分子名称: | Glutamine synthetase | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.13 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TF6
 | | S. aureus GS(12)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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7TFC
 | | B. subtilis GS(14)-Q-GlnR peptide | | 分子名称: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | | 著者 | Travis, B.A, Peck, J, Schumacher, M.A. | | 登録日 | 2022-01-06 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | | 主引用文献 | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
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6UZB
 | | Anthrax toxin protective antigen channels bound to edema factor | | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
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1GJB
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-27 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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7TFF
 | | Crystal structure of human platelet phosphofructokinase-1 mutant- D564N | | 分子名称: | ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ... | | 著者 | Hansen, H, Webb, B.A, Robart, A.R, Narayanasami, S. | | 登録日 | 2022-01-06 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity.
Biochem.J., 480, 2023
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6UZE
 | | Anthrax toxin protective antigen channels bound to edema factor | | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | | 登録日 | 2019-11-15 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
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6UZD
 | | Anthrax toxin protective antigen channels bound to edema factor | | 分子名称: | CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen | | 著者 | Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A. | | 登録日 | 2019-11-14 | | 公開日 | 2020-03-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
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1GJC
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-27 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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1GJD
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | CITRIC ACID, N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-05-03 | | 公開日 | 2002-05-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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6V1I
 | | Cryo-EM reconstruction of the thermophilic bacteriophage P74-26 small terminase- symmetric | | 分子名称: | Small terminase protein | | 著者 | Hayes, J.A, Hilbert, B.J, Gaubitz, C, Stone, N.P, Kelch, B.A. | | 登録日 | 2019-11-20 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry.
J.Biol.Chem., 295, 2020
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1GJ7
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-27 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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7U1A
 | | RFC:PCNA bound to dsDNA with a ssDNA gap of six nucleotides | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ... | | 著者 | Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. | | 登録日 | 2022-02-20 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
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7U1P
 | | RFC:PCNA bound to DNA with a ssDNA gap of five nucleotides | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA - Primer, DNA - Template, ... | | 著者 | Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. | | 登録日 | 2022-02-21 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
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7U19
 | | RFC:PCNA bound to nicked DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ... | | 著者 | Liu, X, Gaubitz, C, Pajak, J, Kelch, B.A. | | 登録日 | 2022-02-20 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A second DNA binding site on RFC facilitates clamp loading at gapped or nicked DNA.
Elife, 11, 2022
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1GJ9
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | 6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-30 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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1GJ6
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | 6-CHLORO-2-(2-HYDROXY-BIPHENYL-3-YL)-1H-INDOLE-5-CARBOXAMIDINE, BETA-TRYPSIN, CALCIUM ION | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-27 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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1GJA
 | | ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | | 分子名称: | CITRIC ACID, N-(4-CARBAMIMIDOYL-PHENYL)-2-HYDROXY-BENZAMIDE, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | | 登録日 | 2001-04-27 | | 公開日 | 2002-04-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Chem.Biol., 8, 2001
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