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6K3D
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BU of 6k3d by Molmil
Structure of multicopper oxidase mutant
分子名称: COPPER (II) ION, CU-O-CU LINKAGE, Multicopper oxidase
著者Sakuraba, H, Ohshida, T, Satomura, T, Yoneda, K, Ohshima, T.
登録日2019-05-17
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.919 Å)
主引用文献Activity enhancement of multicopper oxidase from a hyperthermophile via directed evolution, and its application as the element of a high performance biocathode.
J.Biotechnol., 325, 2021
7QWT
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BU of 7qwt by Molmil
Rieske non-heme iron monooxygenase for guaiacol O-demethylation
分子名称: FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, Rieske (2Fe-2S) domain protein
著者Hinchen, D.J, Zahn, M, Bleem, A, Beckham, G.T, McGeehan, J.E.
登録日2022-01-25
公開日2022-06-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.712 Å)
主引用文献Discovery, characterization, and metabolic engineering of Rieske non-heme iron monooxygenases for guaiacol O-demethylation
Chem Catal, 2022
3A0I
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BU of 3a0i by Molmil
Human glucokinase in complex with a synthetic activator
分子名称: 3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide, Glucokinase, SODIUM ION, ...
著者Kamata, K, Mitsuya, M.
登録日2009-03-19
公開日2009-04-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators
Bioorg.Med.Chem.Lett., 19, 2009
2D0K
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BU of 2d0k by Molmil
Methionine-free mutant of Escherichia coli dihydrofolate reductase
分子名称: CHLORIDE ION, Dihydrofolate reductase, FOLIC ACID
著者Katayanagi, K.
登録日2005-08-04
公開日2006-02-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolutional Design of a Hyperactive Cysteine- and Methionine-free Mutant of Escherichia coli Dihydrofolate Reductase
J.Biol.Chem., 281, 2006
5K7K
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BU of 5k7k by Molmil
Design and Optimization of Biaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7: Discovery of Clinical Candidate PF-05089771
分子名称: 4-[4-chloranyl-2-(1~{H}-pyrazol-4-yl)phenoxy]-3-cyano-~{N}-(1,3-thiazol-2-yl)benzenesulfonamide, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE
著者Swain, N, Chrencik, J.
登録日2016-05-26
公開日2017-06-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.
J. Med. Chem., 60, 2017
7CJ4
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BU of 7cj4 by Molmil
Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp.
分子名称: Epimerase, MANGANESE (II) ION
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CJ9
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BU of 7cj9 by Molmil
Crystal structure of N-terminal His-tagged D-allulose 3-epimerase from Methylomonas sp. with additional C-terminal residues
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-fructose, ...
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CJ7
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BU of 7cj7 by Molmil
Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp. in complex with L-tagatose
分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol, Epimerase, L-sorbose, ...
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CJ6
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BU of 7cj6 by Molmil
Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp. in complex with D-allulose
分子名称: D-psicose, Epimerase, MANGANESE (II) ION
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CJ8
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BU of 7cj8 by Molmil
Crystal structure of N-terminal His-tagged D-allulose 3-epimerase from Methylomonas sp. in complex with D-allulose
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-psicose, Epimerase, ...
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CJ5
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BU of 7cj5 by Molmil
Crystal structure of homo dimeric D-allulose 3-epimerase from Methylomonas sp. in complex with D-fructose
分子名称: D-fructose, Epimerase, MAGNESIUM ION, ...
著者Yoshida, H, Yoshihara, A, Kamitori, S.
登録日2020-07-09
公開日2021-04-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a novel homodimeric l-ribulose 3-epimerase from Methylomonus sp.
Febs Open Bio, 11, 2021
7CQD
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BU of 7cqd by Molmil
The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 235 and 236
分子名称: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ...
著者Tamura-Sakaguchi, R, Aruga, R, Nogi, T.
登録日2020-08-10
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.
Acta Crystallogr D Struct Biol, 77, 2021
7CQC
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BU of 7cqc by Molmil
The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 181 and 184
分子名称: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ...
著者Aruga, R, Tamura-Sakaguchi, R, Nogi, T.
登録日2020-08-10
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.
Acta Crystallogr D Struct Biol, 77, 2021
2DJW
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BU of 2djw by Molmil
Crystal structure of TTHA0845 from Thermus thermophilus HB8
分子名称: ZINC ION, probable transcriptional regulator, AsnC family
著者Okazaki, N, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-05
公開日2006-09-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the stand-alone RAM-domain protein from Thermus thermophilus HB8
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
3B1M
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BU of 3b1m by Molmil
Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Cerco-A
分子名称: (9aS)-8-acetyl-N-[(2-ethylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
著者Matsui, Y, Hiroyuki, H.
登録日2011-07-05
公開日2011-08-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor gamma Ligand, Cerco-A
Biol.Pharm.Bull., 34, 2011
7EXE
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BU of 7exe by Molmil
Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide
分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22
著者Yan, L, Okatsu, K, Fukai, S.
登録日2021-05-27
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice
Cell Rep, 2021
3A1H
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BU of 3a1h by Molmil
Crystal Structure Analysis of the Collagen-like Peptide, (PPG)4-OTG-(PPG)4
分子名称: collagen-like peptide
著者Okuyama, K, Miyama, K, Mizuno, K, Bachinger, H.P.
登録日2009-04-03
公開日2010-03-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Stabilization of triple-helical structures of collagen peptides containing a Hyp-Thr-Gly, Hyp-Val-Gly, or Hyp-Ser-Gly sequence.
Biopolymers, 95, 2011
1BDD
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BU of 1bdd by Molmil
STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: STAPHYLOCOCCUS AUREUS PROTEIN A
著者Gouda, H, Torigoe, H, Saito, A, Sato, M, Arata, Y, Shimada, I.
登録日1996-06-28
公開日1997-01-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the B domain of staphylococcal protein A: comparisons of the solution and crystal structures.
Biochemistry, 31, 1992
1BDC
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BU of 1bdc by Molmil
STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, 10 STRUCTURES
分子名称: STAPHYLOCOCCUS AUREUS PROTEIN A
著者Gouda, H, Torigoe, H, Saito, A, Sato, M, Arata, Y, Shimada, I.
登録日1996-06-28
公開日1997-01-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the B domain of staphylococcal protein A: comparisons of the solution and crystal structures.
Biochemistry, 31, 1992
6ITZ
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BU of 6itz by Molmil
Peroxiredoxin from Thermococcus kodakaraensis
分子名称: Peroxiredoxin
著者Nakamura, T, Himiyama, T.
登録日2018-11-27
公開日2019-03-06
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
J.Biochem., 166, 2019
6IU1
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BU of 6iu1 by Molmil
Peroxiredoxin from Pyrococcus horikoshii 0Cys mutant)
分子名称: Peroxiredoxin
著者Nakamura, T, Himiyama, T.
登録日2018-11-27
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
J.Biochem., 166, 2019
4G6V
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BU of 4g6v by Molmil
CdiA-CT/CdiI toxin and immunity complex from Burkholderia pseudomallei
分子名称: Adhesin/hemolysin, BROMIDE ION, CdiI
著者Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W.
登録日2012-07-19
公開日2012-12-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
4G6U
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BU of 4g6u by Molmil
CdiA-CT/CdiI toxin and immunity complex from Escherichia coli
分子名称: ACETATE ION, CHLORIDE ION, EC869 CdiA-CT, ...
著者Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W.
登録日2012-07-19
公開日2012-12-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.353 Å)
主引用文献Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
2NSQ
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BU of 2nsq by Molmil
Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-11-06
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
7VWF
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BU of 7vwf by Molmil
Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic agonist TIPP204
分子名称: (2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acid, Peroxisome proliferator-activated receptor delta, heptyl beta-D-glucopyranoside
著者Oyama, T, Miyachi, H.
登録日2021-11-10
公開日2022-02-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor delta in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative.
Acta Crystallogr.,Sect.F, 78, 2022

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件を2024-08-07に公開中

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