1JJI
 
 | | The Crystal Structure of a Hyper-thermophilic Carboxylesterase from the Archaeon Archaeoglobus fulgidus | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carboxylesterase | | 著者 | De Simone, G, Menchise, V, Manco, G, Mandrich, L, Sorrentino, N, Lang, D, Rossi, M, Pedone, C. | | 登録日 | 2001-07-06 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus.
J.Mol.Biol., 314, 2001
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6HXE
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1C7E
 | | D95E HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS | | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | | 著者 | McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D. | | 登録日 | 2000-02-16 | | 公開日 | 2000-08-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin
Biochemistry, 41, 2002
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1JRX
 | | Crystal structure of Arg402Ala mutant flavocytochrome c3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C, FUMARIC ACID, ... | | 著者 | Mowat, C.G, Moysey, R, Miles, C.S, Leys, D, Doherty, M.K, Taylor, P, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2001-08-15 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Kinetic and crystallographic analysis of the key active site acid/base arginine in a soluble fumarate reductase.
Biochemistry, 40, 2001
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4KVQ
 | | Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound | | 分子名称: | Aldehyde decarbonylase, FE (III) ION, PALMITIC ACID | | 著者 | Levy, C.W, Khara, B, Menon, N, Mansell, D, Das, D, Marsh, E.N.G, Leys, D, Scrutton, N.S. | | 登録日 | 2013-05-23 | | 公開日 | 2013-06-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | | 主引用文献 | Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase.
Chembiochem, 14, 2013
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7NRU
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6HGW
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1A27
 | | HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 C-TERMINAL DELETION MUTANT COMPLEXED WITH ESTRADIOL AND NADP+ | | 分子名称: | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Mazza, C, Breton, R, Housset, D, Fontecilla-Camps, J.-C. | | 登録日 | 1998-01-16 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Human Type I 17Beta-Hydroxysteroid Dehydrogenase: Site Directed Mutagenesis and X-Ray Crystallography Structure-Function Analysis
Thesis, Universite Joseph Fourier, 1997
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1KMT
 | | Crystal structure of RhoGDI Glu(154,155)Ala mutant | | 分子名称: | Rho GDP-dissociation inhibitor 1 | | 著者 | Mateja, A, Devedjiev, Y, Krowarsh, D, Longenecker, K, Dauter, Z, Otlewski, J, Derewenda, Z.S. | | 登録日 | 2001-12-17 | | 公開日 | 2002-12-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
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1KSU
 | | Crystal Structure of His505Tyr Mutant Flavocytochrome c3 from Shewanella frigidimarina | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, FUMARIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Pankhurst, K.L, Mowat, C.G, Miles, C.S, Leys, D, Walkinshaw, M.D, Reid, G.A, Chapman, S.K. | | 登録日 | 2002-01-14 | | 公開日 | 2002-08-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Role of His505 in the soluble fumarate reductase from Shewanella frigidimarina.
Biochemistry, 41, 2002
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1YJ9
 | | Crystal Structure Of The Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui Containing a three residue deletion in L22 | | 分子名称: | 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... | | 著者 | Tu, D, Blaha, G, Moore, P.B, Steitz, T.A. | | 登録日 | 2005-01-13 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
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1A3E
 | | COMPLEX OF HUMAN ALPHA-THROMBIN WITH THE BIFUNCTIONAL BORONATE INHIBITOR BOROLOG2 | | 分子名称: | ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BOROLOG2, ... | | 著者 | Skordalakes, E, Elgendy, S, Goodwin, C.A, Green, D, Scullly, M.F, Kakkar, V.V, Freyssinet, J.M, Dodson, G, Deadman, J. | | 登録日 | 1998-01-21 | | 公開日 | 1998-06-03 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide.
Biochemistry, 37, 1998
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1YJN
 | | Crystal Structure Of Clindamycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui | | 分子名称: | 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... | | 著者 | Tu, D, Blaha, G, Moore, P.B, Steitz, T.A. | | 登録日 | 2005-01-14 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
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1AAM
 | | THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI | | 分子名称: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Almo, S.C, Smith, D.L, Danishefsky, A.T, Ringe, D. | | 登録日 | 1993-07-13 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Protein Eng., 7, 1994
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3FPF
 | | Crystal Structure of MtNAS in complex with MTA and tNA | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, BROMIDE ION, N-[(3S)-3-{[(3S)-3-amino-3-carboxypropyl]amino}-3-carboxypropyl]-L-glutamic acid, ... | | 著者 | Dreyfus, C, Pignol, D, Arnoux, P. | | 登録日 | 2009-01-05 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Crystallographic snapshots of iterative substrate translocations during nicotianamine synthesis in Archaea
Proc.Natl.Acad.Sci.USA, 106, 2009
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6GYP
 | | Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore | | 分子名称: | ARGININE, ASPARAGINE, Centromere DNA-binding protein complex CBF3 subunit A, ... | | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | | 登録日 | 2018-07-01 | | 公開日 | 2018-12-05 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
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1XS0
 | | Structure of the E. coli Ivy protein | | 分子名称: | Inhibitor of vertebrate lysozyme | | 著者 | Abergel, C, Monchois, V, Byrn, D, Lazzaroni, J.C, Claverie, J.M. | | 登録日 | 2004-10-18 | | 公開日 | 2004-11-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structure and evolution of the Ivy protein family, unexpected lysozyme inhibitors in Gram-negative bacteria.
Proc.Natl.Acad.Sci.USA, 104, 2007
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6GYS
 | | Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore | | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | | 登録日 | 2018-07-01 | | 公開日 | 2018-12-05 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
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8WX7
 | | Crystal structure of SHP2 in complex with JAB-3186 | | 分子名称: | (5~{S})-1'-[6-azanyl-5-(2-azanyl-3-chloranyl-pyridin-4-yl)sulfanyl-pyrazin-2-yl]spiro[5,7-dihydrocyclopenta[b]pyridine-6,4'-piperidine]-5-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Ma, C, Gao, P, Kang, D, Han, H, Sun, X, Zhang, W, Qian, D, Wang, Y, Long, W. | | 登録日 | 2023-10-27 | | 公開日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Discovery of JAB-3312, a Potent SHP2 Allosteric Inhibitor for Cancer Treatment.
J.Med.Chem., 2024
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3FPH
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5K54
 | | Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state | | 分子名称: | Fructose-1,6-bisphosphatase isozyme 2 | | 著者 | Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D. | | 登録日 | 2016-05-23 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.717 Å) | | 主引用文献 | Structural studies of human muscle FBPase
To Be Published
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8PVZ
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1XO1
 | | T5 5'-EXONUCLEASE MUTANT K83A | | 分子名称: | 5'-EXONUCLEASE | | 著者 | Ceska, T.A, Suck, D, Sayers, J.R. | | 登録日 | 1998-11-19 | | 公開日 | 1999-04-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.
Proc.Natl.Acad.Sci.USA, 96, 1999
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3FTL
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1YJW
 | | Crystal Structure Of Quinupristin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui | | 分子名称: | 23S RIBOSOMAL RNA, 50S ribosomal protein L10, 50S ribosomal protein L10e, ... | | 著者 | Tu, D, Blaha, G, Moore, P.B, Steitz, T.A. | | 登録日 | 2005-01-15 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
Cell(Cambridge,Mass.), 121, 2005
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