3PFV
 
 | | Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide | | 分子名称: | 1,2-ETHANEDIOL, 11-meric peptide from Epidermal growth factor receptor, CHLORIDE ION, ... | | 著者 | Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Muniz, J.R.C, Vollmar, M, Canning, P, Gileadi, O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | | 登録日 | 2010-10-29 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide
To be Published
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2XZZ
 | | Crystal structure of the human transglutaminase 1 beta-barrel domain | | 分子名称: | PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K | | 著者 | Vollmar, M, Krysztofinska, E, Krojer, T, Yue, W.W, Cooper, C, Kavanagh, K, Allerston, C, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the Human Transglutaminase 1 Beta-Barrel Domain
To be Published
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3PFN
 | | Crystal Structure of human NAD kinase | | 分子名称: | NAD kinase, UNKNOWN ATOM OR ION | | 著者 | Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-10-28 | | 公開日 | 2010-11-10 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of human NAD kinase
to be published
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3N8E
 | | Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin) | | 分子名称: | Stress-70 protein, mitochondrial | | 著者 | Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-05-28 | | 公開日 | 2010-06-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Substrate binding domain of the human Heat Shock 70kDa protein 9 (mortalin)
To be published
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3SMP
 | | Monoclinic crystal structure of human pantothenate kinase 1 alpha | | 分子名称: | ACETYL COENZYME *A, ARSENIC, CHLORIDE ION, ... | | 著者 | Guan, X, Tempel, W, Hong, B, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-28 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Monoclinic crystal structure of human pantothenate kinase 1 alpha
to be published
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2VKP
 | | Crystal structure of BTB domain from BTBD6 | | 分子名称: | 1,2-ETHANEDIOL, BTB/POZ DOMAIN-CONTAINING PROTEIN 6, POTASSIUM ION | | 著者 | Cooper, C.D.O, Pike, A.C.W, Salah, E, Filippakopoulos, P, Bunkoczi, G, Elkins, J.M, von Delft, F, Gileadi, O, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S. | | 登録日 | 2007-12-21 | | 公開日 | 2008-02-12 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Btb Domain from Btbd6
To be Published
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2PLA
 | | Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein | | 分子名称: | CHLORIDE ION, Glycerol-3-phosphate dehydrogenase 1-like protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Uppenberg, J, Smee, C, Hozjan, V, Kavanagh, K, Bunkoczi, G, Papagrigoriou, E, Pike, A.C.W, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-19 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of human glycerol-3-phosphate dehydrogenase 1-like protein.
To be Published
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2Y05
 | | Crystal structure of human leukotriene B4 12-hydroxydehydrogenase in complex with NADP and raloxifene | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Yue, W.W, Shafqat, N, Krojer, T, Pike, A.C.W, von Delft, F, Sethi, R, Savitsky, P, Johansson, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2010-11-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Human Leukotriene B4 12-Hydroxydehydrogenase in Complex with Nadp and Raloxifene
To be Published
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3SM9
 | | Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist | | 分子名称: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, CHLORIDE ION, Metabotropic glutamate receptor 3, ... | | 著者 | Wernimont, A.K, Dong, A, Seitova, A, Crombet, L, Khutoreskaya, G, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Cossar, D, Dobrovetsky, E, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-27 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist
TO BE PUBLISHED
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2Q0V
 | | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum | | 分子名称: | PHOSPHATE ION, Ubiquitin-conjugating enzyme E2, putative | | 著者 | Wernimont, A.K, Lew, J, Hassanali, A, Lin, L, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC) | | 登録日 | 2007-05-22 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of ubiquitin conjugating enzyme E2, putative, from Plasmodium falciparum.
To be Published
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3MTG
 | | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative adenosylhomocysteinase 2 | | 著者 | Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-04-30 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
TO BE PUBLISHED
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3Q5L
 | | Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin | | 分子名称: | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-{[2-(pyrrolidin-1-yl)ethyl]amino}-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, Heat shock protein 83-1 | | 著者 | Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2010-12-28 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K 213 in the presence of 17-AEP-geldanamycin.
To be Published
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3IUG
 | | Crystal structure of the RhoGAP domain of RICS | | 分子名称: | Rho/Cdc42/Rac GTPase-activating protein RICS, UNKNOWN ATOM OR ION | | 著者 | Nedyalkova, L, Tempel, W, Tong, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-08-31 | | 公開日 | 2009-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of the RhoGAP domain of RICS
to be published
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2X7H
 | | Crystal structure of the human MGC45594 gene product in complex with fenoprofen | | 分子名称: | 1,2-ETHANEDIOL, FENOPROFEN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Shafqat, N, Yue, W.W, Ugochukwu, E, Niesen, F, Vollmar, M, Chaikuad, A, Pike, A.C.W, von Delft, F, Smee, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2010-02-26 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Human Mgc45594 Gene Product in Complex with Fenoprofen
To be Published
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3G0L
 | | Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B | | 著者 | Filippakopoulos, P, Keates, T, Salah, E, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-01-28 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal Structure of Human Bromodomain Adjacent to Zinc finger domain 2B (BAZ2B)
To be Published
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3HM8
 | | Crystal structure of the C-terminal Hexokinase domain of human HK3 | | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, Hexokinase-3, alpha-D-glucopyranose | | 著者 | Nedyalkova, L, Tong, Y, Rabeh, W, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-05-28 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the C-terminal Hexokinase domain of human HK3
To be Published
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2X1H
 | | Crystal structure of the human MGC45594 gene product in complex with raloxifene | | 分子名称: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, ... | | 著者 | Shafqat, N, Yue, W.W, Pike, A.C.W, Niesen, F, Ugochukwu, E, Krojer, T, Chaikuad, A, Smee, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2009-12-24 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of the Human Mgc45594 Gene Product in Complex with Raloxifene
To be Published
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2PLW
 | | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052). | | 分子名称: | Ribosomal RNA methyltransferase, putative, S-ADENOSYLMETHIONINE, ... | | 著者 | Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-20 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052).
To be Published
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3QF9
 | | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand | | 分子名称: | 6-{5-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl}-N-{3-[(4-ethylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}naphthalene-1-carboxamide, CHLORIDE ION, Proto-oncogene serine/threonine-protein kinase pim-1, ... | | 著者 | Filippakopoulos, P, Bullock, A.N, Fedorov, O, Miduturu, C.V, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Grey, N, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-01-21 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand
To be Published
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2WWE
 | | Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma | | 分子名称: | PHOSPHOINOSITIDE-3-KINASE, CLASS 2, GAMMA POLYPEPTIDE | | 著者 | Roos, A.K, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Van Der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-10-22 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Crystal Structure of the Phox Homology Domain of Human Phosphoinositide-3-Kinase-C2-Gamma
To be Published
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3QIJ
 | | Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R | | 分子名称: | Protein 4.1, UNKNOWN ATOM OR ION | | 著者 | Nedyalkova, L, Zhong, N, Tong, Y, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-01-27 | | 公開日 | 2011-02-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Primitive-monoclinic crystal structure of the FERM domain of protein 4.1R
to be published
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3Q5K
 | | Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor | | 分子名称: | 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-{[2-(methylsulfanyl)ethyl]amino}benzamide, Heat shock protein 83-1 | | 著者 | Wernimont, A.K, Tempel, W, Lin, Y.H, Hutchinson, A, MacKenzie, F, Fairlamb, A, Cossar, D, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2010-12-28 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor
To be Published
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2WWY
 | | Structure of human RECQ-like helicase in complex with a DNA substrate | | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*DA DG DC DG DT DC DG DA DG DA DT DC DCP)-3', ATP-DEPENDENT DNA HELICASE Q1, ... | | 著者 | Pike, A.C.W, Zhang, Y, Schnecke, C, Chaikuad, A, Krojer, T, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gileadi, O. | | 登録日 | 2009-10-30 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures
Proc.Natl.Acad.Sci.USA, 112, 2015
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3Q3J
 | | Crystal structure of plexin A2 RBD in complex with Rnd1 | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A2, ... | | 著者 | Wang, H, Tempel, W, Tong, Y, Guan, X, Shen, L, Buren, L, Zhang, N, Wernimont, A.K, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-12-21 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.971 Å) | | 主引用文献 | Crystal structure of plexin A2 RBD in complex with Rnd1
to be published
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2XRI
 | | Crystal structure of human ERI1 exoribonuclease 3 | | 分子名称: | ERI1 EXORIBONUCLEASE 3, GLYCEROL, MAGNESIUM ION | | 著者 | Welin, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Wahlberg, E, Weigelt, J, Nordlund, P. | | 登録日 | 2010-09-15 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal Structure of Human Eri1 Exoribonuclease 3
To be Published
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