2Y05

Crystal structure of human leukotriene B4 12-hydroxydehydrogenase in complex with NADP and raloxifene

Summary for 2Y05

• Entry DOI: 10.2210/pdb2y05/pdb
• Related: 1ZSV
• Descriptor: PROSTAGLANDIN REDUCTASE 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RALOXIFENE, ... (6 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: Q14914
• Total number of polymer chains: 4
• Total formula weight: 147686.73

Authors

Yue, W.W.,Shafqat, N.,Krojer, T.,Pike, A.C.W.,von Delft, F.,Sethi, R.,Savitsky, P.,Johansson, C.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2010-11-30, release date: 2011-01-26, Last modification date: 2023-12-20)

• Primary citation: Yue, W.W.,Shafqat, N.,Krojer, T.,Pike, A.C.W.,von Delft, F.,Sethi, R.,Savitsky, P.,Johansson, C.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.; Crystal Structure of Human Leukotriene B4 12-Hydroxydehydrogenase in Complex with Nadp and Raloxifene; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)