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3Q6Q
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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q6R
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BU of 3q6r by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lex
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Chen, L, Georgiev, I, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R6K
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BU of 3r6k by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, VP1 protein, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
登録日2011-03-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
5X72
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BU of 5x72 by Molmil
The crystal Structure PDE delta in complex with (rac)-p9
分子名称: (2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, (2S)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
著者Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C.
登録日2017-02-23
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors
J. Med. Chem., 60, 2017
4OU3
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BU of 4ou3 by Molmil
Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
著者Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F.
登録日2014-02-14
公開日2014-11-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy.
J.Biol.Chem., 289, 2014
4Q5J
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BU of 4q5j by Molmil
Crystal structure of SeMet derivative BRI1 in complex with BKI1
分子名称: BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein BRASSINOSTEROID INSENSITIVE 1
著者Wang, J, Wang, J, Chen, L, Wu, J.W, Wang, Z.X.
登録日2014-04-17
公開日2014-10-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.772 Å)
主引用文献Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
Cell Res., 24, 2014
4PGO
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BU of 4pgo by Molmil
Crystal structure of hypothetical protein PF0907 from Pyrococcus furiosus solved by sulfur SAD using Swiss Light Source data
分子名称: CHLORIDE ION, Uncharacterized protein
著者Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2014-05-02
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4PII
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Crystal structure of hypothetical protein PF0907 from pyrococcus furiosus solved by sulfur SAD using Swiss light source data
分子名称: CHLORIDE ION, IMIDAZOLE, N-glycosylase/DNA lyase
著者Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2014-05-08
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4QE7
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BU of 4qe7 by Molmil
Open MthK pore structure soaked in 10 mM Ba2+/100 mM Na+
分子名称: BARIUM ION, Calcium-gated potassium channel MthK
著者Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S.
登録日2014-05-15
公開日2014-07-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ionic interactions of Ba2+ blockades in the MthK K+ channel
J.Gen.Physiol., 144, 2014
4QE9
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Open MthK pore structure soaked in 10 mM Ba2+/100 mM K+
分子名称: Calcium-gated potassium channel MthK, POTASSIUM ION
著者Guo, R, Zeng, W, Cui, H, Chen, L, Ye, S.
登録日2014-05-15
公開日2014-07-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Ionic interactions of Ba2+ blockades in the MthK K+ channel
J.Gen.Physiol., 144, 2014
4TN8
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BU of 4tn8 by Molmil
Crystal structure of Thermus Thermophilus thioredoxin solved by sulfur SAD using Swiss Light Source data
分子名称: CHLORIDE ION, Thioredoxin
著者Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2014-06-03
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
8IOW
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BU of 8iow by Molmil
Cryo-EM structure of the sarilumab Fab/IL-6R complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Sarilumab Fab, Interleukin-6 receptor subunit alpha, ...
著者She, J, Chen, L, Wang, M.X.
登録日2023-03-13
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the sarilumab Fab/IL-6R complex
To Be Published
7F6J
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BU of 7f6j by Molmil
Crystal structure of the PDZD8 coiled-coil domain - Rab7 complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PDZ domain-containing protein 8, ...
著者Khan, H, Chen, L, Tan, L, Im, Y.J.
登録日2021-06-25
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of human PDZD8-Rab7 interaction for the ER-late endosome tethering.
Sci Rep, 11, 2021
7ULB
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BU of 7ulb by Molmil
recombinant Mambalgin-1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Mambalgin-1
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-04
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of recombinant mambalgin at 2.49 Angstroms resolution.
To Be Published
7ULR
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BU of 7ulr by Molmil
recombinant kappa-bungarotoxin
分子名称: Kappa-bungarotoxin
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of recombinant kappa-bungarotoxin at 1.8 Angstroms resolution.
To Be Published
7ULS
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BU of 7uls by Molmil
Recombinant muscarinic toxin alpha
分子名称: GLYCEROL, Muscarinic toxin alpha
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献recombinant MTalpha at 1.8 Angstroms resolution
To Be Published
7ULG
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BU of 7ulg by Molmil
recombinant alpha cobra toxin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Alpha-cobratoxin
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-04
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure of recombinant alpha cobra toxin at 1.57 Angstroms
To Be Published
7ULQ
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BU of 7ulq by Molmil
Recombinant Hannalgesin
分子名称: ACETATE ION, GLYCEROL, Long neurotoxin OH-55, ...
著者Xu, J, Lei, X, Chen, L.
登録日2022-04-05
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of recombinant Hannalgesin at 2.2 Angstroms resolution.
To Be Published
4N8R
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BU of 4n8r by Molmil
Crystal structure of RXRa LBD complexed with a synthetic modulator K-8008
分子名称: 5-(2-{(1Z)-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha
著者Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C.
登録日2013-10-17
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
4N5G
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Crystal Structure of RXRa LBD complexed with a synthetic modulator K8012
分子名称: 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole, Retinoic acid receptor RXR-alpha
著者Aleshin, A.E, Su, Y, Zhang, X, Liddington, R.C.
登録日2013-10-09
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
5J14
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BU of 5j14 by Molmil
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3
分子名称: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Putative secreted endoglycosylceramidase, ...
著者Chen, L.
登録日2016-03-28
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.915 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
5J7Z
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Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM1
分子名称: N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)STEARAMIDE, Putative secreted endoglycosylceramidase, SODIUM ION, ...
著者Chen, L.
登録日2016-04-07
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases.
J. Biol. Chem., 292, 2017
5TBP
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BU of 5tbp by Molmil
Crystal Structure of RXR-alpha ligand binding domain complexed with synthetic modulator K8003
分子名称: ACETATE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Aleshin, A.E, Liddington, R.C, Su, Y, Zhang, X.
登録日2016-09-12
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha.
Nat Commun, 8, 2017
4F2L
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BU of 4f2l by Molmil
Structure of a regulatory domain of AMPK
分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION
著者Xin, F.J, Zhang, Y.Y, Wang, J, Wang, Z.X, Wu, J.W.
登録日2012-05-08
公開日2013-06-26
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conserved regulatory elements in AMPK
Nature, 498, 2013
6PNX
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Crystal Structure of an Asymmetric Dimer of FGF Receptor 3 Kinases Trapped in A-loop Tyrosine Transphosphorylation Reaction
分子名称: Fibroblast growth factor receptor 3, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Mohammadi, M.
登録日2019-07-03
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation.
Nat.Chem.Biol., 16, 2020

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