6QJQ
 
 | | Cryo-EM structure of heparin-induced 2N3R tau filaments | | 分子名称: | Microtubule-associated protein tau | | 著者 | Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W. | | 登録日 | 2019-01-24 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
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1UUB
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1LD4
 | | Placement of the Structural Proteins in Sindbis Virus | | 分子名称: | Coat protein C, GENERAL CONTROL PROTEIN GCN4, Spike glycoprotein E1, ... | | 著者 | Zhang, W, Mukhopadhyay, S, Pletnev, S.V, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2002-04-08 | | 公開日 | 2002-11-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (11.4 Å) | | 主引用文献 | Placement of the Structural Proteins in Sindbis virus
J.VIROL., 76, 2002
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5KRG
 | | RNA 15mer duplex binding with PZG monomer | | 分子名称: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3'), [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid | | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | | 登録日 | 2016-07-07 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
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5L00
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5DHB
 | | Cooperativity and Downstream Binding in RNA Replication | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, RNA (5'-R(*(LCC)P*(TLN)P*(LCG)P*UP*AP*CP*A)-3') | | 著者 | Zhang, W, Fahrenbach, A.C, Tam, C.P, Szostak, J.W. | | 登録日 | 2015-08-30 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
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5DHC
 | | Cooperativity and Downstream Binding in RNA Replication | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') | | 著者 | Zhang, W, Fahrenbach, A.C, Tam, C.P, Szostak, J.W. | | 登録日 | 2015-08-30 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Unusual Base-Pairing Interactions in Monomer-Template Complexes.
ACS Cent Sci, 2, 2016
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1OR4
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4IAA
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine | | 分子名称: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | | 登録日 | 2012-12-06 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine
To be Published
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4XAH
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1OR6
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4YDU
 | | Crystal structure of E. coli YgjD-YeaZ heterodimer in complex with ADP | | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | | 著者 | Zhang, W, Collinet, B, Perrochia, L, Durand, D, Van Tilbeurgh, H. | | 登録日 | 2015-02-23 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.
Nucleic Acids Res., 43, 2015
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4RC4
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4RBL
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives | | 分子名称: | 1,4,5,8-tetrahydroxyanthracene-9,10-dione, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Wan, X, Huang, N. | | 登録日 | 2014-09-12 | | 公開日 | 2015-03-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives
To be Published, 2014
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4RC3
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4RC2
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6CAB
 | | RNA-dGMP complex with Sr ion | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), STRONTIUM ION | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-29 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8E
 | | RNA-imidazolium-bridged intermediate complex, 4h soaking | | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-24 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8I
 | | RNA-activated 2-AIpG monomer complex, 5 min soaking | | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-24 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8L
 | | RNA-activated 2-AIpG monomer complex, 1h soaking | | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8D
 | | RNA-dGMP complex with Mg ion | | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-24 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6BMD
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6C8K
 | | RNA-activated 2-AIpG monomer complex, 30 min soaking | | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-24 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.259 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8O
 | | RNA-activated 2-AIpG monomer, 3h soaking | | 分子名称: | 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3') | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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6C8M
 | | RNA-activated 2-AIpG monomer, 1.5h soaking | | 分子名称: | 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]guanosine, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), ... | | 著者 | Zhang, W, Szostak, J.W. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallographic observation of nonenzymatic RNA primer extension.
Elife, 7, 2018
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