4N09
 
 | | Structure of Trypanosoma brucei brucei adenosine kinase in complex with adenosine and AMPPNP | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Timm, J, Gonzalez-Pacanowska, D, Wilson, K.S. | | 登録日 | 2013-10-01 | | 公開日 | 2014-01-15 | | 最終更新日 | 2014-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of adenosine kinase from Trypanosoma brucei brucei.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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2V1C
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1PYC
 | | CYP1 (HAP1) DNA-BINDING DOMAIN (RESIDUES 60-100), NMR, 15 STRUCTURES | | 分子名称: | CYP1, ZINC ION | | 著者 | Timmerman, J, Vuidepot, A.-L, Bontems, F, Lallemand, J.-Y, Gervais, M, Shechter, E, Guiard, B. | | 登録日 | 1996-02-17 | | 公開日 | 1996-08-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, 15N resonance assignment and three-dimensional structure of CYP1 (HAP1) DNA-binding domain.
J.Mol.Biol., 259, 1996
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2VF7
 | | Crystal structure of UvrA2 from Deinococcus radiodurans | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, EXCINUCLEASE ABC, SUBUNIT A., ... | | 著者 | Timmins, J, Gordon, E, Caria, S, Leonard, G, Kuo, M.S, Monchois, V, McSweeney, S. | | 登録日 | 2007-10-31 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and mutational analyses of Deinococcus radiodurans UvrA2 provide insight into DNA binding and damage recognition by UvrAs.
Structure, 17, 2009
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2VF8
 | | Crystal structure of UvrA2 from Deinococcus radiodurans | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, EXCINUCLEASE ABC SUBUNIT A, PHOSPHATE ION, ... | | 著者 | Timmins, J, Gordon, E, Caria, S, Leonard, G, Kuo, M.S, Monchois, V, McSweeney, S. | | 登録日 | 2007-10-31 | | 公開日 | 2008-12-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and Mutational Analyses of Deinococcus Radiodurans Uvra2 Provide Insight Into DNA Binding and Damage Recognition by Uvras.
Structure, 17, 2009
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2BHY
 | | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase in complex with trehalose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | | 著者 | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | | 登録日 | 2005-01-20 | | 公開日 | 2005-03-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides
J.Mol.Biol., 347, 2005
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2BHU
 | | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, MALTOOLIGOSYLTREHALOSE TREHALOHYDROLASE, ... | | 著者 | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | | 登録日 | 2005-01-18 | | 公開日 | 2005-03-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides
J.Mol.Biol., 347, 2005
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2BHZ
 | | Crystal structure of Deinococcus radiodurans maltooligosyltrehalose trehalohydrolase in complex with maltose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, MAGNESIUM ION, ... | | 著者 | Timmins, J, Leiros, H.-K.S, Leonard, G, Leiros, I, McSweeney, S. | | 登録日 | 2005-01-20 | | 公開日 | 2005-03-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal Structure of Maltooligosyltrehalose Trehalohydrolase from Deinococcus Radiodurans in Complex with Disaccharides
J.Mol.Biol., 347, 2005
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4AOZ
 | | B. subtilis dUTPase YncF in complex with dU, PPi and Mg (P212121) | | 分子名称: | 2'-DEOXYURIDINE, ACETATE ION, CHLORIDE ION, ... | | 著者 | Timm, J, Garcia-Nafria, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. | | 登録日 | 2012-03-30 | | 公開日 | 2013-05-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
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4B0H
 | | B. subtilis dUTPase YncF in complex with dU, PPi and Mg b (P212121) | | 分子名称: | 2'-DEOXYURIDINE, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Timm, J, Garcia-Nafria, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. | | 登録日 | 2012-07-02 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
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5FUW
 | | catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP or dThd | | 分子名称: | PHOSPHATE ION, THYMDINE KINASE, THYMIDINE, ... | | 著者 | Timm, J, Valente, M, Castillo-Acosta, V, Balzarini, T, Nettleship, J.E, Rada, H, Wilson, K.S, Gonzalez-Pacanowska, D. | | 登録日 | 2016-01-31 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.
Mol.Microbiol., 102, 2016
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5FUV
 | | catalytic domain of Thymidine kinase from Trypanosoma brucei with dThd | | 分子名称: | GLYCEROL, PHOSPHATE ION, THYMDINE KINASE, ... | | 著者 | Timm, J, Valente, M, Castillo-Acosta, V, Balzarini, T, Nettleship, J.E, Rada, H, Wilson, K.S, Gonzalez-Pacanowska, D. | | 登録日 | 2016-01-31 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.
Mol.Microbiol., 102, 2016
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5FUX
 | | catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, THYMDINE KINASE, ... | | 著者 | Timm, J, Valente, M, Castillo-Acosta, V, Balzarini, T, Nettleship, J.E, Rada, H, Wilson, K.S, Gonzalez-Pacanowska, D. | | 登録日 | 2016-01-31 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.
Mol.Microbiol., 102, 2016
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5FUY
 | | catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP | | 分子名称: | PHOSPHATE ION, THYMDINE KINASE, ZINC ION, ... | | 著者 | Timm, J, Valente, M, Castillo-Acosta, V, Balzarini, T, Nettleship, J.E, Rada, H, Wilson, K.S, Gonzalez-Pacanowska, D. | | 登録日 | 2016-01-31 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.
Mol.Microbiol., 102, 2016
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8B0Q
 | | Deinococcus radiodurans UvrC C-terminal half | | 分子名称: | UvrABC system protein C | | 著者 | Timmins, J, Stelter, M. | | 登録日 | 2022-09-08 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER.
Nucleic Acids Res., 51, 2023
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6HK5
 | | X-ray structure of a truncated mutant of the metallochaperone CooJ with a high-affinity nickel-binding site | | 分子名称: | 3,3',3''-phosphoryltripropanoic acid, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Alfano, M, Perard, J, Basset, C, Carpentier, P, Zambelli, B, Timm, J, Crouzy, S, Ciurli, S, Cavazza, C. | | 登録日 | 2018-09-05 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.042 Å) | | 主引用文献 | The carbon monoxide dehydrogenase accessory protein CooJ is a histidine-rich multidomain dimer containing an unexpected Ni(II)-binding site.
J.Biol.Chem., 294, 2019
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4APZ
 | | Structure of B. subtilis genomic dUTPase YncF in complex with dU, PPi and Mg in P1 | | 分子名称: | 2'-DEOXYURIDINE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Garcia-Nafria, J, Timm, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. | | 登録日 | 2012-04-11 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
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4AOO
 | | B. subtilis dUTPase YncF in complex with dU PPi and Mg in H32 | | 分子名称: | 2'-DEOXYURIDINE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Garcia-Nafria, J, Timm, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. | | 登録日 | 2012-03-29 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism
Acta Crystallogr.,Sect.D, 69, 2013
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7L8I
 | | SARS-CoV-2 Main Protease (Mpro) in Complex with Rupintrivir (P21) | | 分子名称: | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lockbaum, G.J, Henes, M, Lee, J.M, Timm, J, Nalivaika, E.A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | 登録日 | 2020-12-31 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.
Biochemistry, 60, 2021
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7L8J
 | | SARS-CoV-2 Main Protease (Mpro) in Complex with Rupintrivir (P21212) | | 分子名称: | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lockbaum, G.J, Henes, M, Lee, J.M, Timm, J, Nalivaika, E.A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | 登録日 | 2020-12-31 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.
Biochemistry, 60, 2021
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7L8H
 | | EV68 3C protease (3Cpro) in Complex with Rupintrivir | | 分子名称: | 3C Protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Lockbaum, G.J, Henes, M, Lee, J.M, Timm, J, Nalivaika, E.A, Yilmaz, N.K, Thompson, P.R, Schiffer, C.A. | | 登録日 | 2020-12-31 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode.
Biochemistry, 60, 2021
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1T3E
 | | Structural basis of dynamic glycine receptor clustering | | 分子名称: | 49-mer fragment of Glycine receptor beta chain, Gephyrin, SULFATE ION | | 著者 | Sola, M, Bavro, V.N, Timmins, J, Franz, T, Ricard-Blum, S, Schoehn, G, Ruigrok, R.W.H, Paarmann, I, Saiyed, T, O'Sullivan, G.A. | | 登録日 | 2004-04-26 | | 公開日 | 2004-07-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural basis of dynamic glycine receptor clustering by gephyrin
Embo J., 23, 2004
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4JCV
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4UOB
 | | Crystal structure of Deinococcus radiodurans Endonuclease III-3 | | 分子名称: | ACETATE ION, COBALT (II) ION, ENDONUCLEASE III-3, ... | | 著者 | Sarre, A, Okvist, M, Klar, T, Hall, D, Smalas, A.O, McSweeney, S, Timmins, J, Moe, E. | | 登録日 | 2014-06-02 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Structural and Functional Characterization of Two Unusual Endonuclease III Enzymes from Deinococcus Radiodurans.
J.Struct.Biol., 191, 2015
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4UNF
 | | Crystal structure of Deinococcus radiodurans Endonuclease III-1 | | 分子名称: | ACETATE ION, ENDONUCLEASE III-1, IRON/SULFUR CLUSTER, ... | | 著者 | Sarre, A, Okvist, M, Klar, T, Hall, D, Smalas, A.O, McSweeney, S, Timmins, J, Moe, E. | | 登録日 | 2014-05-28 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural and Functional Characterization of Two Unusual Endonuclease III Enzymes from Deinococcus Radiodurans.
J.Struct.Biol., 191, 2015
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