5FUX

catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP

Summary for 5FUX

• Entry DOI: 10.2210/pdb5fux/pdb
• Related: 5FUV 5FUW 5FUY
• Descriptor: THYMDINE KINASE, MAGNESIUM ION, ZINC ION, ... (6 entities in total)
• Functional Keywords: transferase, transefrase, thymidine kinase, t.brucei, tbtk, tkii, dtmp
• Biological source: TRYPANOSOMA BRUCEI
• Total number of polymer chains: 2
• Total formula weight: 42000.26

Authors

Timm, J.,Valente, M.,Castillo-Acosta, V.,Balzarini, T.,Nettleship, J.E.,Rada, H.,Wilson, K.S.,Gonzalez-Pacanowska, D. (deposition date: 2016-01-31, release date: 2016-07-27, Last modification date: 2024-01-10)

• Primary citation: Valente, M.,Timm, J.,Castillo-Acosta, V.M.,Ruiz-Perez, L.M.,Balzarini, T.,Nettleship, J.E.,Bird, L.E.,Rada, H.,Wilson, K.S.,Gonzalez-Pacanowska, D.; Cell Cycle Regulation and Novel Structural Features of Thymidine Kinase, an Essential Enzyme in Trypanosoma Brucei.; Mol.Microbiol., 102:365-, 2016; PubMed: 27426054; DOI: 10.1111/MMI.13467

Experimental method

X-RAY DIFFRACTION (2.2 Å)