3TRS
 
 | | The crystal structure of aspergilloglutamic peptidase from Aspergillus niger | | 分子名称: | Aspergillopepsin-2 heavy chain, Aspergillopepsin-2 light chain, DIMETHYL SULFOXIDE | | 著者 | Sasaki, H, Kubota, K, Lee, W.C, Ohtsuka, J, Kojima, M, Takahashi, K, Tanokura, M. | | 登録日 | 2011-09-10 | | 公開日 | 2012-08-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of an intermediate dimer of aspergilloglutamic peptidase that mimics the enzyme-activation product complex produced upon autoproteolysis.
J.Biochem., 152, 2012
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3JRQ
 | | Crystal structure of (+)-ABA-bound PYL1 in complex with ABI1 | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Protein phosphatase 2C 56, Putative uncharacterized protein At5g46790 | | 著者 | Miyazono, K, Miyakawa, T, Sawano, Y, Kubota, K, Tanokura, M. | | 登録日 | 2009-09-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of abscisic acid signalling
Nature, 462, 2009
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3JRS
 | | Crystal structure of (+)-ABA-bound PYL1 | | 分子名称: | (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At5g46790 | | 著者 | Miyazono, K, Miyakawa, T, Sawano, Y, Kubota, K, Tanokura, M. | | 登録日 | 2009-09-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural basis of abscisic acid signalling
Nature, 462, 2009
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3VS9
 | | Crystal structure of type III PKS ArsC mutant | | 分子名称: | SODIUM ION, TETRAETHYLENE GLYCOL, Type III polyketide synthase | | 著者 | Satou, R, Miyanaga, A, Ozawa, H, Funa, N, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | | 登録日 | 2012-04-23 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity
J.Biol.Chem., 288, 2013
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3VGK
 | | Crystal structure of a ROK family glucokinase from Streptomyces griseus | | 分子名称: | Glucokinase, SULFATE ION, ZINC ION | | 著者 | Miyazono, K, Tabei, N, Morita, S, Ohnishi, Y, Horinouchi, S, Tanokura, M. | | 登録日 | 2011-08-15 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus
J.Bacteriol., 194, 2012
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3VS8
 | | Crystal structure of type III PKS ArsC | | 分子名称: | SODIUM ION, Type III polyketide synthase | | 著者 | Satou, R, Miyanaga, A, Ozawa, H, Funa, N, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. | | 登録日 | 2012-04-23 | | 公開日 | 2013-04-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity
J.Biol.Chem., 288, 2013
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3VTG
 | | High choriolytic enzyme 1 (HCE-1), a hatching enzyme zinc-protease from Oryzias latipes (Medaka fish) | | 分子名称: | High choriolytic enzyme 1, ZINC ION | | 著者 | Kudo, N, Yasumasu, S, Iuchi, I, Tanokura, M. | | 登録日 | 2012-05-30 | | 公開日 | 2013-06-05 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Crystal Structure of High choriolytic enzyme 1 (HCE-1), a hatching enzyme from Oryzias latipes (Medaka fish)
To be Published
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3VGM
 | | Crystal structure of a ROK family glucokinase from Streptomyces griseus in complex with glucose | | 分子名称: | Glucokinase, POTASSIUM ION, ZINC ION, ... | | 著者 | Miyazono, K, Tabei, N, Morita, S, Ohnishi, Y, Horinouchi, S, Tanokura, M. | | 登録日 | 2011-08-15 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Substrate recognition mechanism and substrate-dependent conformational changes of an ROK family glucokinase from Streptomyces griseus
J.Bacteriol., 194, 2012
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4TMC
 | | CRYSTAL STRUCTURE of OLD YELLOW ENZYME from CANDIDA MACEDONIENSIS AKU4588 COMPLEXED with P-HYDROXYBENZALDEHYDE | | 分子名称: | FLAVIN MONONUCLEOTIDE, Old yellow enzyme, P-HYDROXYBENZALDEHYDE | | 著者 | Horita, S, Kataoka, M, Kitamura, N, Nakagawa, T, Miyakawa, T, Ohtsuka, J, Nagata, K, Shimizu, S, Tanokura, M. | | 登録日 | 2014-05-31 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | An Engineered Old Yellow Enzyme that Enables Efficient Synthesis of (4R,6R)-Actinol in a One-Pot Reduction System
Chembiochem, 16, 2015
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4TMB
 | | CRYSTAL STRUCTURE of OLD YELLOW ENZYME from CANDIDA MACEDONIENSIS AKU4588 | | 分子名称: | FLAVIN MONONUCLEOTIDE, Old yellow enzyme | | 著者 | Horita, S, Kataoka, M, Kitamura, N, Nakagawa, T, Miyakawa, T, Ohtsuka, J, Nagata, K, Shimizu, S, Tanokura, M. | | 登録日 | 2014-05-31 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | An Engineered Old Yellow Enzyme that Enables Efficient Synthesis of (4R,6R)-Actinol in a One-Pot Reduction System
Chembiochem, 16, 2015
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4QLX
 | | Crystal structure of CLA-ER with product binding | | 分子名称: | 10-oxooctadecanoic acid, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Hou, F, Miyakawa, T, Tanokura, M. | | 登録日 | 2014-06-13 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure and reaction mechanism of a novel enone reductase.
Febs J., 282, 2015
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4QLY
 | | Crystal structure of CLA-ER, a novel enone reductase catalyzing a key step of a gut-bacterial fatty acid saturation metabolism, biohydrogenation | | 分子名称: | Enone reductase CLA-ER, FLAVIN MONONUCLEOTIDE | | 著者 | Hou, F, Miyakawa, T, Tanokura, M. | | 登録日 | 2014-06-13 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Structure and reaction mechanism of a novel enone reductase.
Febs J., 282, 2015
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3TZ1
 | | Crystal structure of the Ca2+-saturated C-terminal domain of Akazara scallop troponin C in complex with a troponin I fragment | | 分子名称: | CALCIUM ION, Troponin C, Troponin I | | 著者 | Yumoto, F, Kato, Y.S, Ohtsuki, I, Tanokura, M. | | 登録日 | 2011-09-26 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the Ca2+-saturated C-terminal domain of scallop troponin C in complex with a troponin I fragment
Biol.Chem., 394, 2012
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2GXG
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2KSW
 | | Backbone 1H, 13C, and 15N Chemical Shift Assignments for Oryctin | | 分子名称: | Oryctin | | 著者 | Horita, S, Ishibashi, J, Nagata, K, Miyakawa, T, Yamakawa, M, Tanokura, M. | | 登録日 | 2010-01-14 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Isolation, cDNA cloning, and structure-based functional characterization of oryctin, a hemolymph protein from the coconut rhinoceros beetle, Oryctes rhinoceros, as a novel serine protease inhibitor
J.Biol.Chem., 285, 2010
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1IX5
 | | Solution structure of the Methanococcus thermolithotrophicus FKBP | | 分子名称: | FKBP | | 著者 | Suzuki, R, Nagata, K, Kawakami, M, Nemoto, N, Furutani, M, Adachi, K, Maruyama, T, Tanokura, M. | | 登録日 | 2002-06-12 | | 公開日 | 2003-06-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional Solution Structure of an Archaeal FKBP with a Dual Function of Peptidyl Prolyl cis-trans Isomerase and Chaperone-like Activities
J.MOL.BIOL., 328, 2003
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5GWT
 | | 4-hydroxyisoleucine dehydrogenase mutant complexed with NADH and succinate | | 分子名称: | 4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID | | 著者 | Shi, X, Miyakawa, T, Nakamura, A, Tanokura, M. | | 登録日 | 2016-09-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
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5GWS
 | | 4-hydroxyisoleucine dehydrogenase complexed with NADH and succinate | | 分子名称: | 4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SUCCINIC ACID | | 著者 | Shi, X, Miyakawa, T, Nakamura, A, Tanokura, M. | | 登録日 | 2016-09-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers.
Sci Rep, 7, 2017
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5GWR
 | | 4-hydroxyisoleucine dehydrogenase complexed with NADH | | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxyisolecuine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Shi, X, Miyakawa, T, Nakamura, A, Tanokura, M. | | 登録日 | 2016-09-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Engineering a short-chain dehydrogenase/reductase for the stereoselective production of (2S,3R,4S)-4-hydroxyisoleucine with three asymmetric centers
Sci Rep, 7, 2017
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1ZOV
 | | Crystal Structure of Monomeric Sarcosine Oxidase from Bacillus sp. NS-129 | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Monomeric sarcosine oxidase | | 著者 | Nagata, K, Sasaki, H, Ohtsuka, J, Hua, M, Okai, M, Kubota, K, Kamo, M, Ito, K, Ichikawa, T, Koyama, Y, Tanokura, M. | | 登録日 | 2005-05-14 | | 公開日 | 2006-05-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal structure of monomeric sarcosine oxidase from Bacillus sp. NS-129 reveals multiple conformations at the active-site loop
PROC.JPN.ACAD.,SER.B, 81, 2005
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3LNQ
 | | Structure of Aristaless homeodomain in complex with DNA | | 分子名称: | 5'-D(*CP*CP*CP*TP*AP*AP*TP*TP*AP*AP*AP*CP*CP*C)-3', 5'-D(*GP*GP*GP*TP*TP*TP*AP*AP*TP*TP*AP*GP*GP*G)-3', ACETATE ION, ... | | 著者 | Takamura, Y, Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. | | 登録日 | 2010-02-02 | | 公開日 | 2010-04-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless
Embo J., 29, 2010
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2LDS
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1ION
 | | THE SEPTUM SITE-DETERMINING PROTEIN MIND COMPLEXED WITH MG-ADP FROM PYROCOCCUS HORIKOSHII OT3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROBABLE CELL DIVISION INHIBITOR MIND | | 著者 | Sakai, N, Yao, M, Itou, H, Watanabe, N, Yumoto, F, Tanokura, M, Tanaka, I. | | 登録日 | 2001-03-21 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The three-dimensional structure of septum site-determining protein MinD from Pyrococcus horikoshii OT3 in complex with Mg-ADP.
Structure, 9, 2001
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7BQV
 | | Cereblon in complex with SALL4 and (S)-5-hydroxythalidomide | | 分子名称: | 2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-5-oxidanyl-isoindole-1,3-dione, Protein cereblon, SULFATE ION, ... | | 著者 | Furihata, H, Miyauchi, Y, Asano, A, Tanokura, M, Miyakawa, T. | | 登録日 | 2020-03-25 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide.
Nat Commun, 11, 2020
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7BQU
 | | Cereblon in complex with SALL4 and (S)-thalidomide | | 分子名称: | Protein cereblon, S-Thalidomide, Sal-like protein 4, ... | | 著者 | Furihata, H, Miyauchi, Y, Asano, A, Tanokura, M, Miyakawa, T. | | 登録日 | 2020-03-25 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide.
Nat Commun, 11, 2020
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