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1LB1
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BU of 1lb1 by Molmil
Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
分子名称: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
著者Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
登録日2002-04-01
公開日2002-05-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1JAD
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BU of 1jad by Molmil
C-terminal Domain of Turkey PLC-beta
分子名称: SULFATE ION, phospholipase C beta
著者Singer, A.U, Waldo, G.L, Harden, T.K, Sondek, J.
登録日2001-05-30
公開日2001-12-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A unique fold of phospholipase C-beta mediates dimerization and interaction with G alpha q.
Nat.Struct.Biol., 9, 2002
1TBG
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BU of 1tbg by Molmil
BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN
分子名称: TRANSDUCIN
著者Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B.
登録日1996-06-15
公開日1997-04-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
3GRE
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BU of 3gre by Molmil
Crystal structure of Saccharomyces cerevisiae Vps15 WD repeat domain
分子名称: Serine/threonine-protein kinase VPS15
著者Vanhooke, J.L, Sondek, J, Betts, L.
登録日2009-03-25
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of Vps15 in the endosomal G protein signaling pathway.
Biochemistry, 48, 2009
1STB
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BU of 1stb by Molmil
ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Quirk, S, Gittis, A, Keefe, L.J, Lattman, E.E.
登録日1994-01-17
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.
Protein Sci., 3, 1994
1STA
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BU of 1sta by Molmil
ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Keefe, L.J, Quirk, S, Gittis, A, Lattman, E.E.
登録日1994-01-17
公開日1994-06-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.
Protein Sci., 3, 1994
2GEE
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BU of 2gee by Molmil
Crystal Structure of Human Type III Fibronectin Extradomain B and Domain 8
分子名称: hypothetical protein
著者Bencharit, S, Cui, C.B, Siddiqui, A, Howard-Williams, E.L, Aukhil, I.
登録日2006-03-19
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural insights into fibronectin type III domain-mediated signaling.
J.Mol.Biol., 367, 2007
2TRC
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BU of 2trc by Molmil
PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
分子名称: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN
著者Gaudet, R, Bohm, A, Sigler, P.B.
登録日1997-01-06
公開日1997-06-05
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
1STY
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BU of 1sty by Molmil
THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE
分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
著者Keefe, L.J, Lattman, E.E.
登録日1993-02-18
公開日1993-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献The alpha aneurism: a structural motif revealed in an insertion mutant of staphylococcal nuclease.
Proc.Natl.Acad.Sci.USA, 90, 1993
2XNS
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BU of 2xns by Molmil
Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14
分子名称: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1, GUANOSINE-5'-DIPHOSPHATE, REGULATOR OF G-PROTEIN SIGNALING 14, ...
著者Bosch, D, Sammond, D.W, Butterfoss, G.L, Machius, M, Siderovski, D.P, Kuhlman, B.
登録日2010-08-05
公開日2011-06-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Computational Design of the Sequence and Structure of a Protein-Binding Peptide.
J.Am.Chem.Soc., 133, 2011
1B9X
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BU of 1b9x by Molmil
STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN
分子名称: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
著者Gaudet, R, Sigler, P.B.
登録日1999-02-16
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
1B9Y
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BU of 1b9y by Molmil
STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA
分子名称: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN)
著者Gaudet, R, Sigler, P.B.
登録日1999-02-16
公開日1999-02-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin.
Mol.Cell, 3, 1999
3ONW
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BU of 3onw by Molmil
Structure of a G-alpha-i1 mutant with enhanced affinity for the RGS14 GoLoco motif.
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, Regulator of G-protein signaling 14, ...
著者Bosch, D, Kimple, A.J, Sammond, D.W, Miley, M.J, Machius, M, Kuhlman, B, Willard, F.S, Siderovski, D.P.
登録日2010-08-30
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein {alpha} Subunit Mutants.
J.Biol.Chem., 286, 2011
3QI2
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BU of 3qi2 by Molmil
A Galpha P-loop mutation prevents transition to the activated state: G42R bound to RGS14 GoLoco
分子名称: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Bosch, D.E, Willard, F.S, Kimple, A.J, Miley, M.J, Siderovski, D.P.
登録日2011-01-26
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
Plos Pathog., 8, 2012
3QE0
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BU of 3qe0 by Molmil
A Galpha-i1 P-loop mutation prevents transition to the activated state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, KB752 peptide, ...
著者Bosch, D.E, Willard, F.S, Kimple, A.J, Miley, M.J, Siderovski, D.P.
登録日2011-01-19
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
Plos Pathog., 8, 2012
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