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6N33
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BU of 6n33 by Molmil
Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622
分子名称: 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor
著者Zhang, Y.
登録日2018-11-14
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
Nat Commun, 10, 2019
6SI7
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BU of 6si7 by Molmil
Structure of the curli secretion-assembly complex CsgG:CsgF
分子名称: Curli production assembly/transport component CsgF, Curli production assembly/transport component CsgG
著者Van der Verren, S.E, Remaut, H.
登録日2019-08-08
公開日2020-06-24
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A dual-constriction biological nanopore resolves homonucleotide sequences with high fidelity.
Nat.Biotechnol., 38, 2020
3S36
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BU of 3s36 by Molmil
Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B heavy chain, 1121B light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S35
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BU of 3s35 by Molmil
Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6.64 Fab heavy chain, ...
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S37
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BU of 3s37 by Molmil
Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B Fab heavy chain, 1121B Fab light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S34
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BU of 3s34 by Molmil
Structure of the 1121B Fab fragment
分子名称: 1121B Fab heavy chain, 1121B Fab light chain, PHOSPHATE ION
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3A5U
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BU of 3a5u by Molmil
Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex
分子名称: DNA (31-MER), Single-stranded DNA-binding protein
著者Kaushal, P.S, Manjunath, G.P, Sekar, K, Muniyappa, K, Vijayan, M.
登録日2009-08-12
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Promiscuity and specificity in DNA binding to SSB: Insights from the structure of the Mycobacterium smegmatis SSB-ssDNA complex.
To be Published, 2009
6HZ4
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BU of 6hz4 by Molmil
Structure of McrBC without DNA binding domains (one half of the full complex)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ5
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BU of 6hz5 by Molmil
Structure of McrBC without DNA binding domains (Class 1)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ6
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BU of 6hz6 by Molmil
Structure of McrBC without DNA binding domains (Class 2)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ8
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BU of 6hz8 by Molmil
Structure of McrBC without DNA binding domains (Class 4)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ7
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BU of 6hz7 by Molmil
Structure of McrBC without DNA binding domains (Class 3)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
6HZ9
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BU of 6hz9 by Molmil
Structure of McrBC without DNA binding domains (Class 5)
分子名称: 5-methylcytosine-specific restriction enzyme B, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Itoh, Y, Nirwan, N, Saikrishnan, K, Amunts, A.
登録日2018-10-22
公開日2019-07-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
Nat Commun, 10, 2019
4L9I
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BU of 4l9i by Molmil
Bovine G Protein Coupled Receptor Kinase 1 in Complex with Paroxetine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Paroxetine, ...
著者Homan, K.T, Tesmer, J.J.G.
登録日2013-06-18
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog.
Mol.Pharmacol., 85, 2014
4MK0
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BU of 4mk0 by Molmil
Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed paroxetine derivative
分子名称: 5-{[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-1H-isoindol-1-one, Beta-adrenergic receptor kinase 1, GLYCEROL, ...
著者Homan, K.T, Tesmer, J.J.G.
登録日2013-09-04
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog.
Mol.Pharmacol., 85, 2014
7VSR
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BU of 7vsr by Molmil
Structure of McrBC (stalkless mutant)
分子名称: 5-methylcytosine-specific restriction enzyme B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Saikrishnan, K, Adhav, V.A, Bose, S, Kutti R, V.
登録日2021-10-27
公開日2023-02-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of McrBC (stalkless mutant)
To Be Published
5A5C
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BU of 5a5c by Molmil
Structure of an engineered neuronal LRRTM2 adhesion molecule
分子名称: LRRTM
著者Paatero, A, Rosti, K, Shkumatov, A.V, Brunello, C, Kysenius, K, Huttunen, H, Kajander, T.
登録日2015-06-17
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Crystal Structure of an Engineered Lrrtm2 Synaptic Adhesion Molecule and a Model for Neurexin Binding.
Biochemistry, 55, 2016
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