5U09
 
 | | High-resolution crystal structure of the human CB1 cannabinoid receptor | | 分子名称: | Cannabinoid receptor 1,GlgA glycogen synthase, DI(HYDROXYETHYL)ETHER, N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide, ... | | 著者 | Shao, Z.H, Yin, J, Rosenbaum, D. | | 登録日 | 2016-11-23 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High-resolution crystal structure of the human CB1 cannabinoid receptor.
Nature, 2016
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6KQI
 | | Structure of an allosteric modulator bound to the CB1 cannabinoid receptor | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 5-chloro-3-ethyl-N-{2-[4-(piperidin-1-yl)phenyl]ethyl}-1H-indole-2-carboxamide, ... | | 著者 | Shao, Z.H, Yan, W. | | 登録日 | 2019-08-17 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.245 Å) | | 主引用文献 | Structure of an allosteric modulator bound to the CB1 cannabinoid receptor.
Nat.Chem.Biol., 15, 2019
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8IQH
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8IQB
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8IQD
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8IQC
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8IQI
 | | Structure of Full-Length AsfvPrimPol in Complex-Form | | 分子名称: | DNA (32-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Shao, Z.W, Su, S.C, Gan, J.H. | | 登録日 | 2023-03-16 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structures and implications of the C962R protein of African swine fever virus.
Nucleic Acids Res., 51, 2023
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7YPE
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7YPF
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8SAI
 | | Cryo-EM structure of GPR34-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Yong, X.H, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2023-04-01 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1Y2M
 | | Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides | | 分子名称: | Phenylalanine ammonia-lyase | | 著者 | Wang, L, Gamez, A, Sarkissian, C.N, Straub, M, Patch, M.G, Han, G.W, Scriver, C.R, Stevens, R.C. | | 登録日 | 2004-11-22 | | 公開日 | 2005-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria.
Mol.Genet.Metab., 86, 2005
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7MFH
 | | Crystal structure of BIO-32546 bound mouse Autotaxin | | 分子名称: | (1R,3S,5S)-8-{(1S)-1-[8-(trifluoromethyl)-7-{[(1s,4R)-4-(trifluoromethyl)cyclohexyl]oxy}naphthalen-2-yl]ethyl}-8-azabicyclo[3.2.1]octane-3-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chodaparambil, J.V. | | 登録日 | 2021-04-09 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546.
Acs Med.Chem.Lett., 12, 2021
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6UTK
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8GZJ
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8GZM
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8GZL
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8GZK
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6K9C
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6K9E
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6LRB
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8XIF
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8XJ8
 | | The Cryo-EM structure of MPXV E5 C-terminal in complex with DNA | | 分子名称: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | | 登録日 | 2023-12-20 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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8XIG
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8XJ7
 | | The Cryo-EM structure of MPXV E5 in complex with DNA | | 分子名称: | DNA (70-MER), MAGNESIUM ION, Monkeypox virus E5, ... | | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | | 登録日 | 2023-12-20 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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8XJ6
 | | The Cryo-EM structure of MPXV E5 apo conformation | | 分子名称: | AMP PHOSPHORAMIDATE, Monkeypox virus E5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Zhang, W, Liu, Y, Gao, H, Gan, J. | | 登録日 | 2023-12-20 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
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