8BRV
| Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C complexed with beta3-methionine. | 分子名称: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | 登録日 | 2022-11-24 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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8BRW
| Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C | 分子名称: | Methionine--tRNA ligase, ZINC ION | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | 登録日 | 2022-11-24 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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8BRU
| Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C | 分子名称: | CITRIC ACID, Methionine--tRNA ligase, ZINC ION | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | 登録日 | 2022-11-24 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments. Protein Sci., 32, 2023
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4MNO
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4MO0
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5OCD
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6EZ3
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6FQ2
| Structure of minimal sequence for left -handed G-quadruplex formation | 分子名称: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | 著者 | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | 登録日 | 2018-02-13 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl., 58, 2019
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2MS9
| Solution structure of a G-quadruplex | 分子名称: | DNA (28-MER) | 著者 | Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T. | 登録日 | 2014-07-25 | 公開日 | 2015-02-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a left-handed DNA G-quadruplex Proc.Natl.Acad.Sci.USA, 2015
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5JB3
| Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Coureux, P.-D, Schmitt, E, Mechulam, Y. | 登録日 | 2016-04-13 | 公開日 | 2016-11-30 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (5.34 Å) | 主引用文献 | Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
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5JBH
| Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-IN conformation | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein SX, 30S ribosomal protein eL41, ... | 著者 | Coureux, P.-D, Schmitt, E, Mechulam, Y. | 登録日 | 2016-04-13 | 公開日 | 2016-12-07 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (5.34 Å) | 主引用文献 | Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
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5L4O
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6JCE
| NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes | 分子名称: | 29-mer DNA | 著者 | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2019-01-28 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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7D5F
| Left-handed G-quadruplex containing 3 bulges | 分子名称: | 3xBulge-LHG4motif | 著者 | Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7D5D
| Left-handed G-quadruplex containing one bulge | 分子名称: | 1xBulge-LHG4motif, POTASSIUM ION, SPERMINE | 著者 | Das, P, Ngo, K.H, Winnerdy, F.R, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7D5E
| Left-handed G-quadruplex containing two bulges | 分子名称: | 2xBulge-LHG4motif, POTASSIUM ION, SODIUM ION, ... | 著者 | Das, P, Maity, A, Ngo, K.H, Winnerdy, F.R, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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6Y4B
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6Y3G
| Crystal structure of phenylalanine tRNA from Escherichia coli | 分子名称: | CALCIUM ION, GLYCEROL, GUANIDINE, ... | 著者 | Bourgeois, G, Mechulam, Y, Schmitt, E. | 登録日 | 2020-02-18 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of the interaction between cyclodipeptide synthases and aminoacylated tRNA substrates. Rna, 26, 2020
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7YYP
| Structure of aIF5B from Pyrococcus abyssi complexed with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, NITRATE ION, Probable translation initiation factor IF-2 | 著者 | Bourgeois, G, Schmitt, E, Mechulam, Y, Coureux, P.D, Kazan, R. | 登録日 | 2022-02-18 | 公開日 | 2022-06-29 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Role of aIF5B in archaeal translation initiation. Nucleic Acids Res., 50, 2022
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7YZN
| Structure of C-terminally truncated aIF5B from Pyrococcus abyssi complexed with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable translation initiation factor IF-2, ... | 著者 | Bourgeois, G, Schmitt, E, Mechulam, Y, Coureux, P.D, Kazan, R. | 登録日 | 2022-02-21 | 公開日 | 2022-06-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Role of aIF5B in archaeal translation initiation. Nucleic Acids Res., 50, 2022
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4Q24
| Crystal structure of Cyclo(L-leucyl-L-phenylalanyl) synthase | 分子名称: | Cyclo(L-leucyl-L-phenylalanyl) synthase, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE | 著者 | Moutiez, M, Schmitt, E, Seguin, J, Thai, R, Favry, E, Mechulam, Y, Gondry, M. | 登録日 | 2014-04-07 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases. Nat Commun, 5, 2014
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4RCZ
| Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | 登録日 | 2014-09-18 | 公開日 | 2015-05-27 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.429 Å) | 主引用文献 | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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4RD6
| Structure of aIF2-gamma from Sulfolobus solfataricus bound to GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Translation initiation factor 2 subunit gamma | 著者 | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | 登録日 | 2014-09-18 | 公開日 | 2015-07-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | 主引用文献 | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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4RD1
| Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GTP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | 登録日 | 2014-09-18 | 公開日 | 2015-05-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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4RD3
| Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDP and Pi | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Dubiez, E, Aleksandrov, A, Lazennec-Schurdevin, C, Mechulam, Y, Schmitt, E. | 登録日 | 2014-09-18 | 公開日 | 2015-05-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res., 43, 2015
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