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5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
分子名称: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
著者Renko, M, Gammons, M.V, Bienz, M.
登録日2016-08-05
公開日2016-10-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
6T8G
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BU of 6t8g by Molmil
Stalled FtsK motor domain bound to dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8O
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BU of 6t8o by Molmil
Stalled FtsK motor domain bound to dsDNA end
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T8B
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BU of 6t8b by Molmil
FtsK motor domain with dsDNA, translocating state
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, MAGNESIUM ION, ...
著者Jean, N.L, Lowe, J.
登録日2019-10-24
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
2BTH
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BU of 2bth by Molmil
Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
著者Ferguson, N, Allen, M.D.
登録日2005-05-31
公開日2006-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
2BTG
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BU of 2btg by Molmil
peripheral-subunit binding domains from mesophilic,thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions
分子名称: DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX
著者Ferguson, N, Allen, M.D.
登録日2005-05-31
公開日2006-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
4CKP
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BU of 4ckp by Molmil
Structure of an N-terminal fragment of Leishmania SAS-6 that contains part of its coiled coil domain
分子名称: SAS-6
著者van Breugel, M.
登録日2014-01-07
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
4CKN
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BU of 4ckn by Molmil
Structure of an N-terminal fragment of Leishmania SAS-6 containing parts of its coiled coil domain, F257E mutant
分子名称: SAS-6
著者van Breugel, M.
登録日2014-01-07
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
4CKM
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BU of 4ckm by Molmil
Structure of the N-terminal domain of Leishmania SAS-6
分子名称: GLYCEROL, MAGNESIUM ION, SAS-6
著者van Breugel, M.
登録日2014-01-07
公開日2014-03-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the SAS-6 cartwheel hub from Leishmania major.
Elife, 3, 2014
3SL9
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BU of 3sl9 by Molmil
X-ray structure of Beta catenin in complex with Bcl9
分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ...
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
3SLA
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BU of 3sla by Molmil
X-ray structure of first four repeats of human beta-catenin
分子名称: Catenin beta-1, GLYCEROL, SODIUM ION
著者Gupta, D, Bienz, M.
登録日2011-06-24
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
7O06
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BU of 7o06 by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 10Z
分子名称: Camelid nanobody 10Z, Centrosomal protein of 164 kDa, SULFATE ION
著者e Silva, I.R, van Breugel, M.
登録日2021-03-25
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
7O0S
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BU of 7o0s by Molmil
Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 36Z
分子名称: Centrosomal protein of 164 kDa, Nanobody 36Z
著者e Silva, I.R, van Breugel, M.
登録日2021-03-26
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
6S9R
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BU of 6s9r by Molmil
Crystal structure of SSDP from D. melanogaster
分子名称: Sequence-specific single-stranded DNA-binding protein, isoform A
著者Renko, M, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S9T
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BU of 6s9t by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3
分子名称: Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL
著者Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S9S
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BU of 6s9s by Molmil
Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10
分子名称: Darpin 10, LIM domain-binding protein 1
著者Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M.
登録日2019-07-15
公開日2019-10-09
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
5A7B
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BU of 5a7b by Molmil
Structure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan5211
分子名称: 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C.
登録日2015-07-03
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere.
Acs Chem.Biol., 10, 2015
3VVV
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BU of 3vvv by Molmil
Skich domain of NDP52
分子名称: Calcium-binding and coiled-coil domain-containing protein 2
著者Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D.
登録日2012-07-28
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
3VVW
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BU of 3vvw by Molmil
NDP52 in complex with LC3C
分子名称: Calcium-binding and coiled-coil domain-containing protein 2, Microtubule-associated proteins 1A/1B light chain 3C
著者Akutsu, M, Muhlinen, N.V, Randow, F, Komander, D.
登録日2012-07-28
公開日2013-02-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy
Mol.Cell, 48, 2012
3ZRH
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BU of 3zrh by Molmil
Crystal structure of the Lys29, Lys33-linkage-specific TRABID OTU deubiquitinase domain reveals an Ankyrin-repeat ubiquitin binding domain (AnkUBD)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, UBIQUITIN THIOESTERASE ZRANB1
著者Licchesi, J.D.F, Akutsu, M, Komander, D.
登録日2011-06-16
公開日2011-12-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献An Ankyrin-Repeat Ubiquitin-Binding Domain Determines Trabid'S Specificity for Atypical Ubiquitin Chains.
Nat.Struct.Mol.Biol., 19, 2011
4AGO
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BU of 4ago by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174
分子名称: CELLULAR TUMOR ANTIGEN P53, TERT-BUTYL [3-(3-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4-HYDROXY-5-IODOPHENYL)PROP-2-YN-1-YL]CARBAMATE, ZINC ION
著者Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M.
登録日2012-01-30
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012
4AGM
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BU of 4agm by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5086
分子名称: 2-{[4-(DIETHYLAMINO)PIPERIDIN-1-YL]METHYL}-4,6-DIIODOPHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R.
登録日2012-01-30
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012
4AGP
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BU of 4agp by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176
分子名称: 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-(3-phenoxyprop-1-yn-1-yl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M.
登録日2012-01-30
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012
4AGL
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BU of 4agl by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan784
分子名称: 2,4-BIS(IODANYL)-6-[[METHYL-(1-METHYLPIPERIDIN-4-YL)AMINO]METHYL]PHENOL, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R.
登録日2012-01-30
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012
4AGQ
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BU of 4agq by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5196
分子名称: 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-[3-(phenylamino)prop-1-yn-1-yl]phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Wilcken, R, Boeckler, F.M, Fersht, A.R.
登録日2012-01-30
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012

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