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4NQC
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BU of 4nqc by Molmil
Crystal structure of TCR-MR1 ternary complex and covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2013-11-25
公開日2014-04-16
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
3TO4
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BU of 3to4 by Molmil
Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Patel, O, Rossjohn, J.
登録日2011-09-04
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen.
Proc.Natl.Acad.Sci.USA, 108, 2011
5J6H
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BU of 5j6h by Molmil
Recognition of the MHC class Ib molecule H2-Q10 by the natural killer cell receptor Ly49C
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, Q10 alpha chain, ...
著者Berry, R, Rossjohn, J.
登録日2016-04-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of the Major Histocompatibility Complex (MHC) Class Ib Molecule H2-Q10 by the Natural Killer Cell Receptor Ly49C.
J.Biol.Chem., 291, 2016
1WZ9
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BU of 1wz9 by Molmil
The 2.1 A structure of a tumour suppressing serpin
分子名称: Maspin precursor, SULFATE ION
著者Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C.
登録日2005-03-03
公開日2005-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
3BWA
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BU of 3bwa by Molmil
Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein
分子名称: Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
著者Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
登録日2008-01-08
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
4Y19
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BU of 4y19 by Molmil
immune complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FS18_alpha, FS18_beta, ...
著者Beringer, D.X, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2015-02-07
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Nat.Immunol., 16, 2015
3BZE
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BU of 3bze by Molmil
The human non-classical major histocompatibility complex molecule HLA-E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Hoare, H.L, Sullivan, L.C, Ely, L.K, Beddoe, T, Henderson, K.N, Lin, J, Clements, C.S, Reid, H.H, Brooks, A.G, Rossjohn, J.
登録日2008-01-17
公開日2008-04-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
J.Mol.Biol., 377, 2008
3CDG
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BU of 3cdg by Molmil
Human CD94/NKG2A in complex with HLA-E
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
著者Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J.
登録日2008-02-26
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
1N2R
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BU of 1n2r by Molmil
A natural selected dimorphism in HLA B*44 alters self, peptide reportoire and T cell recognition.
分子名称: ACETIC ACID, Beta-2-microglobulin, HLA DPA*0201 PEPTIDE, ...
著者Macdonald, W.A, Purcell, A.W, Williams, D.S, Mifsud, N, Ely, L.K, Gorman, J.J, Clements, C.S, Kjer-Nielsen, L, Koelle, D.M, Brooks, A.G, Lovrecz, G.O, Lu, L, Rossjohn, J, McCluskey, J.
登録日2002-10-24
公開日2004-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.
J.Exp.Med., 198, 2003
4XXF
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BU of 4xxf by Molmil
L-fuculose 1-phosphate aldolase from Glaciozyma antarctica PI12
分子名称: Fuculose-1-phosphate aldolase, ZINC ION
著者Jaafar, N.R, Abu Bakar, F.D, Abdul Murad, A.M, Illias, R, Littler, D, Beddoe, T, Rossjohn, J, Mahadi, M.N.
登録日2015-01-30
公開日2015-02-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.
Acta Crystallogr.,Sect.F, 72, 2016
4XXC
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BU of 4xxc by Molmil
HLA-B*1801 in complex with a self-peptide, DELEIKAY
分子名称: ACETATE ION, ASP-GLU-LEU-GLU-ILE-LYS-ALA-TYR, Beta-2-microglobulin, ...
著者Hibbert, K.M, Rossjohn, J, Gras, S.
登録日2015-01-30
公開日2015-04-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.426 Å)
主引用文献T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells.
J Immunol., 194, 2015
7SG1
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BU of 7sg1 by Molmil
XPA5 TCR in complex with HLA-DQ2-alpha1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ciacchi, L, Farenc, C, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2021-10-04
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
J.Biol.Chem., 298, 2022
7SG0
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BU of 7sg0 by Molmil
W316 TCR in complex with HLA-DQ2-omega1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DQ2-glia-omega1 peptide, ...
著者Ciacchi, L, Farenc, C, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2021-10-04
公開日2022-02-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
J.Biol.Chem., 298, 2022
7SG2
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BU of 7sg2 by Molmil
XPA5 TCR in complex with HLA-DQ2-omega1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Ciacchi, L, Farenc, C, Petersen, J, Reid, H.H, Rossjohn, J.
登録日2021-10-04
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
J.Biol.Chem., 298, 2022
7RDV
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BU of 7rdv by Molmil
TFH TCR bound to MHC Class II IAd presenting aggrecan epitope
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Aggrecan core peptide, H-2 class II histocompatibility antigen, ...
著者Lim, J.J, Rossjohn, J, Reid, H.
登録日2021-07-11
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.90006614 Å)
主引用文献TFH TCR bound to MHC Class II IAd presenting aggrecan epitope
To Be Published
6U3N
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BU of 6u3n by Molmil
LS2.8/3.15 - DQ2-P.fluor-alpha1a complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ...
著者Petersen, J, Rossjohn, J.
登録日2019-08-22
公開日2019-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
Nat.Struct.Mol.Biol., 27, 2020
6U3O
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BU of 6u3o by Molmil
JR51 DQ2-p.aeru-alpha2a complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ...
著者Petersen, J, Rossjohn, J.
登録日2019-08-22
公開日2019-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.743 Å)
主引用文献T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.
Nat.Struct.Mol.Biol., 27, 2020
1MOV
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BU of 1mov by Molmil
Crystal structure of Coral protein mutant
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Prescott, M, Ling, M, Beddoe, T, Oakley, A.J, Dove, S, Hoegh-Guldberg, O, Devenish, R.J, Rossjohn, J.
登録日2002-09-10
公開日2003-04-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The 2.2 a crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation.
Structure, 11, 2003
1MTP
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BU of 1mtp by Molmil
The X-ray crystal structure of a serpin from a thermophilic prokaryote
分子名称: Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B
著者Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C.
登録日2002-09-21
公開日2003-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment
Structure, 11, 2003
4U6Y
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BU of 4u6y by Molmil
Crystal Structure of HLA-A*0201 in complex with FLNDK, a 15 mer self-peptide
分子名称: Beta-2-microglobulin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Gras, S, Chabrol, E, Rossjohn, J.
登録日2014-07-30
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.467 Å)
主引用文献Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides.
J.Biol.Chem., 290, 2015
4U6X
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BU of 4u6x by Molmil
Crystal Structure of HLA-A*0201 in complex with ALQDA, a 15 mer self-peptide
分子名称: ALQDA peptide, ALQDAGDSSRKEYFI, Beta-2-microglobulin, ...
著者Gras, S, Chabrol, E, Rossjohn, J.
登録日2014-07-30
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides.
J.Biol.Chem., 290, 2015
7UMG
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BU of 7umg by Molmil
Crystal structure of human CD8aa-MR1-Ac-6-FP complex
分子名称: Beta-2-microglobulin, CHLORIDE ION, Major histocompatibility complex class I-related gene protein, ...
著者Awad, W, Rossjohn, J.
登録日2022-04-06
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells.
J.Exp.Med., 219, 2022
6E7D
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BU of 6e7d by Molmil
Structure of the inhibitory NKR-P1B receptor bound to the host-encoded ligand, Clr-b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D, Killer cell lectin-like receptor subfamily B member 1B allele B, ...
著者Balaji, G.R, Rossjohn, J, Berry, R.
登録日2018-07-26
公開日2018-10-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition.
Nat Commun, 9, 2018
4WNQ
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THE MOLECULAR BASES OF DELTA/ALPHA-BETA T-CELL MEDIATED ANTIGEN RECOGNITION
分子名称: TCR Variable Beta 2 (TRBV20) chain and TCR constant Beta chain, TCR Variable Delta 1 chain and TCR constant Alpha chain
著者Pellicci, D.G, Uldrich, A.P, Le Nours, J, Ross, F, Chabrol, E, Eckle, S.B.G, de Boer, R, Lim, R.T, McPherson, K, Besra, G, Howell, A.R, Moretta, L, McCluskey, J, Heemskerk, M.H.M, Gras, S, Rossjohn, J, Godfrey, D.I.
登録日2014-10-14
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The molecular bases of delta / alpha beta T cell-mediated antigen recognition.
J.Exp.Med., 211, 2014
4WO4
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The molecular bases of Delta/Alpha beta T cell-mediated antigen recognition.
分子名称: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Pellicci, D.G, Uldrich, A.P, Le Nours, J, Ross, F, Chabrol, E, Eckle, S.B.G, de Boer, R, Lim, R.T, McPherson, K, Besra, G, Howell, A.R, Moretta, L, McCluskey, J, Heemskerk, M.H.M, Gras, S, Rossjohn, J, Godfrey, D.I.
登録日2014-10-15
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The molecular bases of delta / alpha beta T cell-mediated antigen recognition.
J.Exp.Med., 211, 2014

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