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Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
分子名称:	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Corticoliberin, ...
著者	Pioszak, A.A, Xu, H.E.
登録日	2008-09-14
公開日	2008-09-30
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.96 Å)
主引用文献	Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283, 2008

Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody
分子名称:	5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者	Yan, Y, Murkherjee, S, Zhou, X.E, Xu, T.H, Xu, H.E, Kossiakoff, A.A, Melcher, K.
登録日	2020-07-20
公開日	2021-07-21
最終更新日	2021-12-15
実験手法	ELECTRON MICROSCOPY (3.47 Å)
主引用文献	Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021

Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody
分子名称:	5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ...
著者	Yan, Y, Murkherjee, S, Zhou, X.E, Xu, T.H, Xu, H.E, Kossiakoff, A.A, Melcher, K.
登録日	2020-07-20
公開日	2021-07-21
最終更新日	2021-12-15
実験手法	ELECTRON MICROSCOPY (3.92 Å)
主引用文献	Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021

Prefusion RSV F Bound to RV521
分子名称:	1'-{[5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzimidazol-2-yl]methyl}-6'-fluorospiro[cyclopropane-1,3'-indol]-2'(1'H)-one, Fusion glycoprotein F0, SULFATE ION
著者	McLellan, J.S.
登録日	2020-11-14
公開日	2021-04-21
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.94 Å)
主引用文献	Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. J.Med.Chem., 64, 2021