2OXX
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![BU of 2oxx by Molmil](/molmil-images/mine/2oxx) | Protein kinase CK2 in complex with tetrabromobenzoimidazole derivatives K17, K22 and K32 | 分子名称: | 4,5,6,7-TETRABROMO-1H,3H-BENZIMIDAZOL-2-THIONE, Casein kinase II subunit alpha | 著者 | Battistutta, R, Zanotti, G, Cendron, L. | 登録日 | 2007-02-21 | 公開日 | 2007-09-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The ATP-Binding Site of Protein Kinase CK2 Holds a Positive Electrostatic Area and Conserved Water Molecules. Chembiochem, 8, 2007
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2OXY
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![BU of 2oxy by Molmil](/molmil-images/mine/2oxy) | Protein kinase CK2 in complex with tetrabromobenzoimidazole derivatives K17, K22 and K32 | 分子名称: | 4,5,6,7-TETRABROMO-BENZIMIDAZOLE, Casein kinase II subunit alpha | 著者 | Battistutta, R, Zanotti, G, Cendron, L. | 登録日 | 2007-02-21 | 公開日 | 2007-09-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.812 Å) | 主引用文献 | The ATP-Binding Site of Protein Kinase CK2 Holds a Positive Electrostatic Area and Conserved Water Molecules. Chembiochem, 8, 2007
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2OXD
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![BU of 2oxd by Molmil](/molmil-images/mine/2oxd) | Protein kinase CK2 in complex with tetrabromobenzoimidazole K17, K22 and K32 inhibitors | 分子名称: | 4,5,6,7-TETRABROMO-1H,3H-BENZIMIDAZOL-2-ONE, Casein kinase II subunit alpha | 著者 | Battistutta, R, Zanotti, G, Cendron, L. | 登録日 | 2007-02-20 | 公開日 | 2007-09-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The ATP-Binding Site of Protein Kinase CK2 Holds a Positive Electrostatic Area and Conserved Water Molecules. Chembiochem, 8, 2007
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2QC6
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![BU of 2qc6 by Molmil](/molmil-images/mine/2qc6) | Protein kinase CK2 in complex with DBC | 分子名称: | 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE, Casein kinase II subunit alpha | 著者 | Battistutta, R. | 登録日 | 2007-06-19 | 公開日 | 2008-02-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships. J.Med.Chem., 51, 2008
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3FWQ
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![BU of 3fwq by Molmil](/molmil-images/mine/3fwq) | Inactive conformation of human protein kinase CK2 catalytic subunit | 分子名称: | CHLORIDE ION, Casein kinase II subunit alpha, GLYCEROL, ... | 著者 | Niefind, K, Raaf, J, Issinger, O.G. | 登録日 | 2009-01-19 | 公開日 | 2009-02-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2 J.Mol.Biol., 386, 2009
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3PE1
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![BU of 3pe1 by Molmil](/molmil-images/mine/3pe1) | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-4945 | 分子名称: | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2010-10-25 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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3PE2
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![BU of 3pe2 by Molmil](/molmil-images/mine/3pe2) | Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011 | 分子名称: | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2010-10-25 | 公開日 | 2011-09-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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3R0T
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![BU of 3r0t by Molmil](/molmil-images/mine/3r0t) | Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279 | 分子名称: | 1,2-ETHANEDIOL, 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, ... | 著者 | Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. | 登録日 | 2011-03-09 | 公開日 | 2011-12-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
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4DGN
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![BU of 4dgn by Molmil](/molmil-images/mine/4dgn) | Crystal Structure of maize CK2 in complex with the inhibitor luteolin | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Casein kinase II subunit alpha | 著者 | Lolli, G, Mazzorana, M, Battistutta, R. | 登録日 | 2012-01-26 | 公開日 | 2012-08-01 | 最終更新日 | 2013-01-02 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight. Biochemistry, 51, 2012
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4DGM
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![BU of 4dgm by Molmil](/molmil-images/mine/4dgm) | Crystal Structure of maize CK2 in complex with the inhibitor apigenin | 分子名称: | 1,2-ETHANEDIOL, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Casein kinase II subunit alpha, ... | 著者 | Lolli, G, Mazzorana, M, Battistutta, R. | 登録日 | 2012-01-26 | 公開日 | 2012-08-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight. Biochemistry, 51, 2012
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4DGL
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![BU of 4dgl by Molmil](/molmil-images/mine/4dgl) | |
3Q04
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![BU of 3q04 by Molmil](/molmil-images/mine/3q04) | |
3PWD
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![BU of 3pwd by Molmil](/molmil-images/mine/3pwd) | Crystal structure of maize CK2 in complex with NBC (Z1) | 分子名称: | 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one, Casein kinase II subunit alpha | 著者 | Battistutta, R, Mazzorana, M. | 登録日 | 2010-12-08 | 公開日 | 2011-11-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A Cell.Mol.Life Sci., 69, 2012
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3QA0
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![BU of 3qa0 by Molmil](/molmil-images/mine/3qa0) | |
3Q9Z
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![BU of 3q9z by Molmil](/molmil-images/mine/3q9z) | Crystal structure of human CK2 alpha in complex with Quinalizarin at pH 6.5 | 分子名称: | 1,2,5,8-tetrahydroxyanthracene-9,10-dione, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ... | 著者 | Battistutta, R, Ranchio, A, Papinutto, E. | 登録日 | 2011-01-10 | 公開日 | 2012-01-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2 To be Published
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3Q9X
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![BU of 3q9x by Molmil](/molmil-images/mine/3q9x) | Crystal structure of human CK2 alpha in complex with emodin at pH 6.5 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ... | 著者 | Battistutta, R, Ranchio, A, Papinutto, E. | 登録日 | 2011-01-10 | 公開日 | 2012-01-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2 To be Published
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3Q9Y
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![BU of 3q9y by Molmil](/molmil-images/mine/3q9y) | Crystal structure of human CK2 alpha in complex with Quinalizarin at pH 8.5 | 分子名称: | 1,2,5,8-tetrahydroxyanthracene-9,10-dione, Casein kinase II subunit alpha, SULFATE ION | 著者 | Battistutta, R, Ranchio, A, Papinutto, E. | 登録日 | 2011-01-10 | 公開日 | 2012-01-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2 To be Published
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3Q9W
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![BU of 3q9w by Molmil](/molmil-images/mine/3q9w) | |
3PVG
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![BU of 3pvg by Molmil](/molmil-images/mine/3pvg) | Crystal structure of Z. mays CK2 alpha subunit in complex with the inhibitor 4,5,6,7-tetrabromo-1-carboxymethylbenzimidazole (K68) | 分子名称: | (4,5,6,7-tetrabromo-1H-benzimidazol-1-yl)acetic acid, Casein kinase II subunit alpha | 著者 | Papinutto, E, Franchin, C, Battistutta, R. | 登録日 | 2010-12-07 | 公開日 | 2010-12-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | ATP site-directed inhibitors of protein kinase CK2: an update. Curr Top Med Chem, 11, 2011
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3PZH
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3OFM
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![BU of 3ofm by Molmil](/molmil-images/mine/3ofm) | Structure of a human CK2alpha prime, the paralog isoform of the catalytic subunit of protein kinase CK2 from Homo sapiens | 分子名称: | 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, CHLORIDE ION, Casein kinase II subunit alpha' | 著者 | Bischoff, N, Olsen, B, Raaf, J, Bretner, M, Issinger, O.-G, Niefind, K. | 登録日 | 2010-08-15 | 公開日 | 2011-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of the reduced affinity between the protein kinase CK2 subunits CK2alpha prime and CK2beta J.Mol.Biol., 407, 2011
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