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2D9D
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BU of 2d9d by Molmil
Solution structure of the BAG domain (275-350) of BAG-family molecular chaperone regulator-5
分子名称: BAG family molecular chaperone regulator 5
著者Hatta, R, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-09
公開日2006-12-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
5ZJ6
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BU of 5zj6 by Molmil
Crystal structure of HCK kinase complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
分子名称: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Tyrosine-protein kinase HCK
著者Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M.
登録日2018-03-19
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.
Protein Expr. Purif., 150, 2018
4YN3
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BU of 4yn3 by Molmil
Crystal structure of Cucumisin complex with pro-peptide
分子名称: CHLORIDE ION, Cucumisin, DI(HYDROXYETHYL)ETHER, ...
著者Murayama, K, Kato-Murayama, M, Yokoyama, S, Arima, K, Shirouzu, M.
登録日2015-03-09
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of cucumisin protease activity regulation by its propeptide
J. Biochem., 161, 2017
5B2N
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BU of 5b2n by Molmil
Crystal structure of the light-driven chloride ion-pumping rhodopsin, ClP, from Nonlabens marinus
分子名称: CHLORIDE ION, Chloride pumping rhodopsin, DECANE, ...
著者Hosaka, T, Kimura-Someya, T, Shirouzu, M.
登録日2016-01-20
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献Structural Mechanism for Light-driven Transport by a New Type of Chloride Ion Pump, Nonlabens marinus Rhodopsin-3
J.Biol.Chem., 291, 2016
3AQE
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BU of 3aqe by Molmil
Crystal structure of the extracellular domain of human RAMP2
分子名称: Receptor activity-modifying protein 2
著者Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S.
登録日2010-10-29
公開日2011-11-09
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding
Protein Sci., 21, 2012
3AQF
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BU of 3aqf by Molmil
Crystal structure of the human CRLR/RAMP2 extracellular complex
分子名称: Calcitonin gene-related peptide type 1 receptor, Receptor activity-modifying protein 2
著者Kusano, S, Kukimono-Niino, M, Shirouzu, M, Shindo, T, Yokoyama, S.
登録日2010-10-29
公開日2011-11-02
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding
Protein Sci., 21, 2012
3A98
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Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1
分子名称: Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1
著者Hanawa-Suetsugu, K, Kukimoto-Niino, M, Sekine, S, Ito, T, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
登録日2009-10-21
公開日2010-10-27
最終更新日2019-09-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
3B13
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BU of 3b13 by Molmil
Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant)
分子名称: Dedicator of cytokinesis protein 2, Ras-related C3 botulinum toxin substrate 1
著者Hanawa-Suetsugu, K, Kukimoto-Niino, M, Mishima-Tsumagari, C, Terada, T, Shirouzu, M, Fukui, Y, Yokoyama, S.
登録日2011-06-24
公開日2012-03-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.006 Å)
主引用文献Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
Proc.Natl.Acad.Sci.USA, 109, 2012
3WF5
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BU of 3wf5 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
分子名称: 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF8
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Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate
分子名称: 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF9
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Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate
分子名称: (2S)-1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl (2S)-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.035 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF6
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Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine
分子名称: 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (2.031 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WE4
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BU of 3we4 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole
分子名称: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, Ribosomal protein S6 kinase beta-1, ZINC ION
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-06-29
公開日2014-08-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.995 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF7
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BU of 3wf7 by Molmil
Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
分子名称: 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
著者Niwa, H, Shirouzu, M, Yokoyama, S.
登録日2013-07-17
公開日2014-08-06
最終更新日2014-10-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3VA2
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BU of 3va2 by Molmil
Crystal structure of human Interleukin-5 in complex with its alpha receptor
分子名称: Interleukin-5, Interleukin-5 receptor subunit alpha
著者Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
登録日2011-12-28
公開日2012-07-25
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Structural basis of interleukin-5 dimer recognition by its alpha receptor
Protein Sci., 21, 2012
3AON
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BU of 3aon by Molmil
Crystal structure of the central axis (NtpD-NtpG) in the catalytic portion of Enterococcus hirae V-type sodium ATPase
分子名称: NITRATE ION, V-type sodium ATPase subunit D, V-type sodium ATPase subunit G
著者Saijo, S, Arai, S, Hossain, K.M.M, Yamato, I, Kakinuma, Y, Ishizuka-Katsura, Y, Terada, T, Shirouzu, M, Yokoyama, S, Iwata, S, Murata, T.
登録日2010-10-04
公開日2011-10-05
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the central axis DF complex of the prokaryotic V-ATPase
Proc.Natl.Acad.Sci.USA, 108, 2011
2ZV2
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BU of 2zv2 by Molmil
Crystal structure of human calcium/calmodulin-dependent protein kinase kinase 2, beta, CaMKK2 kinase domain in complex with STO-609
分子名称: 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, Calcium/calmodulin-dependent protein kinase kinase 2
著者Yoshikawa, S, Kukimoto-niino, M, Shirouzu, M, Suzuki, A, Lee, S, Minokoshi, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-10-31
公開日2009-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the Ca2+/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609
J.Biol.Chem., 286, 2011
3WEX
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BU of 3wex by Molmil
Crystal structure of HLA-DP5 in complex with Cry j 1-derived peptide (residues 214-222)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II antigen
著者Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S.
登録日2013-07-16
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the specific recognition of the major antigenic peptide from the Japanese cedar pollen allergen Cry j 1 by HLA-DP5
J. Mol. Biol., 426, 2014
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