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4YDV
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BU of 4ydv by Molmil
STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS
分子名称: HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain, HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region, HIV GP41 PEPTIDE GP41(596-606)
著者Nicely, N.I, Pemble IV, C.W.
登録日2015-02-23
公開日2015-08-12
最終更新日2021-03-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.
Plos Pathog., 11, 2015
5DD6
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BU of 5dd6 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.mut58 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.mut58 FAB LIGHT CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD3
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BU of 5dd3 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD5
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BU of 5dd5 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570.9 FAB HEAVY CHAIN
著者Nicely, N.I, Pemble IV, C.W, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
6ORN
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BU of 6orn by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074
分子名称: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORO
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BU of 6oro by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORQ
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BU of 6orq by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORP
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BU of 6orp by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ...
著者Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
登録日2019-04-30
公開日2019-06-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6P3B
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BU of 6p3b by Molmil
Crystal structure of the anti-HIV antibody DH501 unmutated common ancestor (UCA)
分子名称: 1,2-ETHANEDIOL, DH501UCA Fab Heavy chain, DH501UCA Fab Light chain
著者Nicely, N.I, Saunders, K.O.
登録日2019-05-23
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Cooperation between somatic mutation and germline-encoded residues enable antibody recognition of HIV-1 envelope glycans.
Plos Pathog., 15, 2019
6P8N
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BU of 6p8n by Molmil
Crystal Structure of Antibody P-p1f1 in Complex with eOD-GT8
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2019-06-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell Rep, 29, 2019
6P6F
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BU of 6p6f by Molmil
BG505 SOSIP-I53-50NP
分子名称: I53-50A.1NT1, I53-50B.4PT1
著者Berndsen, Z.T, Ward, A.B.
登録日2019-06-03
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Nat Commun, 10, 2019
6P8M
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BU of 6p8m by Molmil
Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2019-06-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.594 Å)
主引用文献Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization.
Cell Rep, 29, 2019
6VBO
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BU of 6vbo by Molmil
Crystal structure of anti-HIV-1 antibody DH813 bound to gp120 V2 peptide
分子名称: DH813 heavy chain, DH813 light chain, Envelope glycoprotein gp160
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.683 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
6VBQ
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BU of 6vbq by Molmil
Crystal structure of anti-HIV-1 antibody DH822 bound to gp120 V2 peptide
分子名称: DH822 heavy chain, DH822 light chain, Envelope glycoprotein gp160
著者Janus, B.M, Ofek, G.
登録日2019-12-19
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.116 Å)
主引用文献HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020
6VTU
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BU of 6vtu by Molmil
DH717.1 Fab monomer in complex with man9 glycan
分子名称: DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
著者Fera, D, Bronkema, N.
登録日2020-02-13
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
6VO3
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BU of 6vo3 by Molmil
AMC009 SOSIP.v4.2 in complex with PGV04 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ...
著者Cottrell, C.A, de Val, N, Ward, A.B.
登録日2020-01-29
公開日2020-09-23
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
J.Virol., 94, 2020
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
分子名称: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
著者Manne, K, Nicely, N.I, Acharya, P.
登録日2020-07-13
公開日2020-12-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
8DTK
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BU of 8dtk by Molmil
Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
著者May, A.J, Manne, K, Acharya, P.
登録日2022-07-25
公開日2023-08-02
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Biorxiv, 2023
8F5I
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BU of 8f5i by Molmil
SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1
分子名称: DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ...
著者Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
登録日2022-11-14
公開日2023-10-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
8FDO
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BU of 8fdo by Molmil
SARS-CoV-2 fusion peptide epitope scaffold FP15 bound to DH1058
分子名称: DH1058 Heavy chain, DH1058 Light chain, FP15
著者Kapingidza, A.B, Marston, D.J, Wrapp, D, Winters, K, Azoitei, M.L.
登録日2022-12-04
公開日2023-10-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
8F5H
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BU of 8f5h by Molmil
SARS-CoV-2 S2 helix epitope scaffold
分子名称: S2hlx_EX_19
著者Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
登録日2022-11-14
公開日2023-10-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
8G8A
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BU of 8g8a by Molmil
Crystal structure of DH1317.8 Fab in complex with HIV proximal MPER peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1317.8 heavy chain, DH1317.8 light chain, ...
著者Janus, B.M, Astavans, A, Ofek, G.
登録日2023-02-17
公開日2024-05-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 2024
8G8C
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BU of 8g8c by Molmil
Crystal structure of DH1322.1 Fab in complex with HIV proximal MPER peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1322.1 heavy chain, DH1322.1 light chain, ...
著者Niyongabo, A, Janus, B.M, Ofek, G.
登録日2023-02-17
公開日2024-05-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 2024
8G8D
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BU of 8g8d by Molmil
Crystal structure of DH1346 Fab in complex with HIV proximal MPER peptide
分子名称: DH1346 heavy chain, DH1346 light chain, FLUORIDE ION, ...
著者Niyongabo, A, Janus, B.M, Ofek, G.
登録日2023-02-17
公開日2024-05-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 2024
6SNE
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BU of 6sne by Molmil
crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ...
著者Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W.
登録日2019-08-23
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019

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