6CI0
 
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with E101A (II) mutation | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | | 著者 | Liu, J, Hiser, C, Ferguson-Miller, S. | | 登録日 | 2018-02-23 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The K-path entrance in cytochrome c oxidase is defined by mutation of E101 and controlled by an adjacent ligand binding domain.
Biochim. Biophys. Acta, 1859, 2018
|
|
8E7X
 | | RsTSPO A138F with one Heme bound | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
|
|
8E7Y
 | | RsTSPO A138F with two heme bound | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
|
|
8E7Z
 | | RsTSPO mutant -A138F | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein | | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
|
|
8E7W
 | | RsTSPO A139T with Heme | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
|
|
5DUO
 | | Crystal structure of native translocator protein 18kDa (TSPO) from Rhodobacter sphaeroides (A139T Mutant) in C2 space group | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, PROTOPORPHYRIN IX, ... | | 著者 | Li, F, Liu, J, Zheng, Y, Garavito, R.M, Ferguson-Miller, S. | | 登録日 | 2015-09-20 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350, 2015
|
|
6PW1
 | | Cytochrome c Oxidase delta 16 | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | | 著者 | Liu, J, Ferguson-Miller, S. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry.
Biochim Biophys Acta Bioenerg, 1861, 2019
|
|
6PW0
 | | Cytochrome C oxidase delta 6 mutant | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... | | 著者 | Liu, J, Ferguson-Miller, S. | | 登録日 | 2019-07-21 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural changes at the surface of cytochrome c oxidase alter the proton-pumping stoichiometry.
Biochim Biophys Acta Bioenerg, 1861, 2019
|
|
5UQC
 | | Crystal structure of mouse CRMP2 | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2 | | 著者 | Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L. | | 登録日 | 2017-02-07 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.
Channels (Austin), 11, 2017
|
|
3OM3
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation in the reduced state | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-26 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3OMI
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-27 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3OMA
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with K362M mutation | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-26 | | 公開日 | 2011-02-02 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
3OMN
 | | Catalytic core subunits (I and II) of cytochrome C oxidase from Rhodobacter sphaeroides with D132A mutation in the reduced state | | 分子名称: | (2S,3R)-heptane-1,2,3-triol, CADMIUM ION, CALCIUM ION, ... | | 著者 | Liu, J, Qin, L, Ferguson-Miller, S. | | 登録日 | 2010-08-27 | | 公開日 | 2011-02-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2XHU
 | | HCV-J4 NS5B Polymerase Orthorhombic Crystal Form | | 分子名称: | RNA-directed RNA polymerase, SULFATE ION | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-21 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.287 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
|
|
2XI3
 | | HCV-H77 NS5B Polymerase Complexed With GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA-directed RNA polymerase | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-25 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
|
|
2XI2
 | | HCV-H77 NS5B Apo Polymerase | | 分子名称: | RNA-directed RNA polymerase, SULFATE ION | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-25 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
|
|
2XHV
 | | HCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Form | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase, SULFATE ION | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-21 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
|
|
2XHW
 | | HCV-J4 NS5B Polymerase Trigonal Crystal Form | | 分子名称: | RNA-directed RNA polymerase | | 著者 | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | | 登録日 | 2010-06-21 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
J.Biol.Chem., 285, 2010
|
|
1LSS
 | | KTN Mja218 CRYSTAL STRUCTURE IN COMPLEX WITH NAD+ | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Trk system potassium uptake protein trkA homolog | | 著者 | Roosild, T.P, Miller, S, Booth, I.R, Choe, S. | | 登録日 | 2002-05-18 | | 公開日 | 2002-07-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch.
Cell(Cambridge,Mass.), 109, 2002
|
|
1LSU
 | | KTN Bsu222 Crystal Structure in Complex with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Conserved hypothetical protein yuaA | | 著者 | Roosild, T.P, Miller, S, Booth, I.R, Choe, S. | | 登録日 | 2002-05-18 | | 公開日 | 2002-07-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch.
Cell(Cambridge,Mass.), 109, 2002
|
|
1OCY
 | | Structure of the receptor-binding domain of the bacteriophage T4 short tail fibre | | 分子名称: | BACTERIOPHAGE T4 SHORT TAIL FIBRE, CITRIC ACID, SULFATE ION, ... | | 著者 | Thomassen, E, Gielen, G, Schuetz, M, Miller, S, van Raaij, M.J. | | 登録日 | 2003-02-11 | | 公開日 | 2003-07-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Structure of the Receptor-Binding Domain of the Bacteriophage T4 Short Tail Fibre Reveals a Knitted Trimeric Metal-Binding Fold
J.Mol.Biol., 331, 2003
|
|
3R09
 | | Crystal structure of probable HAD family hydrolase from Pseudomonas fluorescens Pf-5 with bound Mg | | 分子名称: | Hydrolase, haloacid dehalogenase-like family, MAGNESIUM ION, ... | | 著者 | Vetting, M.W, Patskovsky, Y, Toro, R, Freeman, J, Miller, S, Sauder, J.M, Burley, S.K, Dunaway-Mariano, D, Allen, K.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI), New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2011-03-07 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of probable HAD family hydrolase from Pseudomonas fluorescens Pf-5 with bound Mg
To be Published
|
|
2WXP
 | | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with GDC-0941. | | 分子名称: | 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | | 著者 | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | | 登録日 | 2009-11-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
|
|
2WXR
 | | The crystal structure of the murine class IA PI 3-kinase p110delta. | | 分子名称: | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | | 著者 | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | | 登録日 | 2009-11-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
|
|
2WXG
 | | The crystal structure of the murine class IA PI 3-kinase p110delta in complex with SW13. | | 分子名称: | 2-{[4-amino-3-(3-fluoro-5-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | | 著者 | Berndt, A, Miller, S, Williams, O, Lee, D.D, Houseman, B.T, Pacold, J.I, Gorrec, F, Hon, W.-C, Liu, Y, Rommel, C, Gaillard, P, Ruckle, T, Schwarz, M.K, Shokat, K.M, Shaw, J.P, Williams, R.L. | | 登録日 | 2009-11-09 | | 公開日 | 2010-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The P110D Structure: Mechanisms for Selectivity and Potency of New Pi(3)K Inhibitors
Nat.Chem.Biol., 6, 2010
|
|
