7RKY
 
 | | Binding mode of US27-Gi-scFv16 in OCL-state | | 分子名称: | Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-07-22 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
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7RKN
 | | Structure of CX3CL1-US28-Gi-scFv16 in OC-state | | 分子名称: | Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ... | | 著者 | Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. | | 登録日 | 2021-07-22 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
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7RKX
 | | Structure of US27-Gi-scFv16 in CL-state | | 分子名称: | Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Tsutsumi, N, Jude, K.M, Garcia, K.C. | | 登録日 | 2021-07-22 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
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7RKM
 | | Structure of CX3CL1-US28-Gi-scFv16 in C-state | | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ... | | 著者 | Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. | | 登録日 | 2021-07-22 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
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7SWQ
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7SVA
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7T90
 | | Cryo-EM structure of ACh-bound M2R-Go signaling complex in S2 state | | 分子名称: | ACETYLCHOLINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | 登録日 | 2021-12-17 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
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7T8X
 | | Cryo-EM structure of ACh-bound M2R-Go signaling complex in S1 state | | 分子名称: | ACETYLCHOLINE, Antibody fragment, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | 登録日 | 2021-12-17 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
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7T96
 | | Cryo-EM structure of S2 state ACh-bound M2R-Go signaling complex with a PAM | | 分子名称: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, ACETYLCHOLINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | 登録日 | 2021-12-18 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
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7T94
 | | Cryo-EM structure of S1 state ACh-bound M2R-Go signaling complex with a PAM | | 分子名称: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, ACETYLCHOLINE, Antibody fragment, ... | | 著者 | Xu, J, Wang, Q, Du, Y, Kobilka, B.K. | | 登録日 | 2021-12-17 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nat Commun, 14, 2023
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1SAC
 | | THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT | | 分子名称: | ACETIC ACID, CALCIUM ION, SERUM AMYLOID P COMPONENT | | 著者 | White, H.E, Emsley, J, O'Hara, B.P, Oliva, G, Srinivasan, N, Tickle, I.J, Blundell, T.L, Pepys, M.B, Wood, S.P. | | 登録日 | 1994-01-27 | | 公開日 | 1994-05-31 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of pentameric human serum amyloid P component.
Nature, 367, 1994
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6K41
 | | cryo-EM structure of alpha2BAR-GoA complex | | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | | 登録日 | 2019-05-23 | | 公開日 | 2020-04-15 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine.
Nat.Chem.Biol., 16, 2020
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6K42
 | | cryo-EM structure of alpha2BAR-Gi1 complex | | 分子名称: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | | 登録日 | 2019-05-23 | | 公開日 | 2020-04-15 | | 最終更新日 | 2020-05-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine.
Nat.Chem.Biol., 16, 2020
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6N4B
 | | Cannabinoid Receptor 1-G Protein Complex | | 分子名称: | CHOLESTEROL, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Krishna Kumar, K, Shalev-Benami, M, Hu, H, Weis, W.I, Kobilka, B.K, Skiniotis, G. | | 登録日 | 2018-11-18 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.
Cell, 176, 2019
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7MFL
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7MFK
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