1ORR
 
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3UYK
 | | Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone | | 分子名称: | (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-2,13-dihydroxy-14-methyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-1H-as-indaceno[3,2-d]oxacyclododecine-7,15-dione, MAGNESIUM ION, NDP-rhamnosyltransferase, ... | | 著者 | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | | 登録日 | 2011-12-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Biochemistry, 51, 2012
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3UYL
 | | Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate | | 分子名称: | MAGNESIUM ION, NDP-rhamnosyltransferase, THYMIDINE-5'-DIPHOSPHATE, ... | | 著者 | Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T. | | 登録日 | 2011-12-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Biochemistry, 51, 2012
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4J1X
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4J1W
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4LEI
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6NKO
 | | Crystal structure of ForH | | 分子名称: | ForH | | 著者 | Zheng, J, Irani, S, Zhang, Y. | | 登録日 | 2019-01-07 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | | 主引用文献 | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis.
J. Am. Chem. Soc., 141, 2019
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2JVN
 | | Domain C of human PARP-1 | | 分子名称: | Poly [ADP-ribose] polymerase 1, ZINC ION | | 著者 | Hoffman, D, Tao, Z, Liu, H. | | 登録日 | 2007-09-24 | | 公開日 | 2008-05-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif.
Biochemistry, 47, 2008
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5TK7
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5TKA
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5TK6
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5UL3
 | | Structure of Cobalamin-dependent S-adenosylmethionine radical enzyme OxsB with aqua-cobalamin bound | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Bridwell-Rabb, J, Drennan, C.L. | | 登録日 | 2017-01-24 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.
Nature, 544, 2017
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5UL2
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5UL4
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5TK8
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5TK9
 | | Structure of the HD-domain phosphohydrolase OxsA with Oxetanocin-A bound | | 分子名称: | MAGNESIUM ION, OxsA protein, [(2S,3R,4R)-4-(6-amino-9H-purin-9-yl)oxetane-2,3-diyl]dimethanol | | 著者 | Bridwell-Rabb, J, Drennan, C.L. | | 登録日 | 2016-10-06 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.843 Å) | | 主引用文献 | An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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8HFD
 | | Crystal structure of allantoinase from E. coli BL21 | | 分子名称: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | | 著者 | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | | 登録日 | 2022-11-10 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis.
Molecules, 28, 2023
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3SCG
 | | Fe(II)-HppE with R-HPP | | 分子名称: | Epoxidase, FE (II) ION, [(2R)-2-hydroxypropyl]phosphonic acid | | 著者 | Drennan, C.L. | | 登録日 | 2011-06-07 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
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3SCH
 | | Co(II)-HppE with R-HPP | | 分子名称: | COBALT (II) ION, Epoxidase, [(2R)-2-hydroxypropyl]phosphonic acid | | 著者 | Drennan, C.L. | | 登録日 | 2011-06-07 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
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3SCF
 | | Fe(II)-HppE with S-HPP and NO | | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, Epoxidase, FE (II) ION, ... | | 著者 | Drennan, C.L. | | 登録日 | 2011-06-07 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.
J.Am.Chem.Soc., 133, 2011
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7V6H
 | | Crystal Structure of the SpnL | | 分子名称: | Cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Wu, H.-H, Ko, T.-P, Liu, H.-W, Tsai, M.-D. | | 登録日 | 2021-08-20 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.054 Å) | | 主引用文献 | Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
J.Am.Chem.Soc., 143, 2021
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8Q72
 | | E. coli plasmid-borne JetABCD(E248A) core in a cleavage-competent state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Circular plasmid DNA (1840-MER), JetA, ... | | 著者 | Roisne-Hamelin, F, Li, Y, Gruber, S. | | 登録日 | 2023-08-15 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Structural basis for plasmid restriction by SMC JET nuclease.
Mol.Cell, 84, 2024
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7VOC
 | | The crystal structure of a Radical SAM Enzyme BlsE involved in the Biosynthesis of Blasticidin S | | 分子名称: | (2~{S},3~{S},4~{S},5~{R},6~{R})-6-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Cytosylglucuronate decarboxylase, GLYCEROL, ... | | 著者 | Hou, X.L, Zhou, J.H. | | 登録日 | 2021-10-13 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.62005424 Å) | | 主引用文献 | Radical S -Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
J.Am.Chem.Soc., 144, 2022
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7VOB
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5Z8A
 | | Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine) | | 分子名称: | (2~{R},3~{R},4~{R},5~{R})-2-[(1~{S},2~{S},3~{R},4~{S},6~{R})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(aminomethyl)-3-azany l-4,5-bis(oxidanyl)oxan-2-yl]oxy-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol, C-6' aminotransferase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Hong, S.K, Cha, S.S. | | 登録日 | 2018-01-31 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | | 主引用文献 | Complete reconstitution of the diverse pathways of gentamicin B biosynthesis.
Nat. Chem. Biol., 15, 2019
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